Comparing GFF386 FitnessBrowser__Phaeo:GFF386 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 18 hits to proteins with known functional sites (download)
7x0rB Crystal structure of substrate binding protein lbp complexed wtih guanosine from clostridium thermocellum (see paper)
38% identity, 88% coverage: 27:317/331 of query aligns to 8:294/313 of 7x0rB
Sites not aligning to the query:
2fqyA Pnra from treponema pallidum complexed with adenosine. (see paper)
35% identity, 88% coverage: 27:317/331 of query aligns to 7:307/316 of 2fqyA
2fqxA Pnra from treponema pallidum complexed with guanosine (see paper)
35% identity, 88% coverage: 27:317/331 of query aligns to 7:307/316 of 2fqxA
2fqwA Pnra from treponema pallidum as purified from e. Coli (bound to inosine) (see paper)
35% identity, 88% coverage: 27:317/331 of query aligns to 7:307/316 of 2fqwA
P29724 Membrane lipoprotein TmpC; Membrane protein C; 35 kDa antigen; Lipoprotein TpN35; Purine nucleoside receptor A; PnrA from Treponema pallidum (strain Nichols) (see 2 papers)
35% identity, 88% coverage: 27:317/331 of query aligns to 44:344/353 of P29724
Sites not aligning to the query:
6yabAAA Lipoprotein (see paper)
34% identity, 89% coverage: 23:317/331 of query aligns to 17:326/329 of 6yabAAA
6ya3A Crystal structure of pnra from s. Pneumoniae in complex with guanosine (see paper)
34% identity, 89% coverage: 23:317/331 of query aligns to 19:328/331 of 6ya3A
6yagA Crystal structure of pnra from s. Pneumoniae in complex with thymidine (see paper)
34% identity, 89% coverage: 23:317/331 of query aligns to 18:327/329 of 6yagA
6ya4A Crystal structure of pnra from s. Pneumoniae in complex with cytidine (see paper)
34% identity, 89% coverage: 23:317/331 of query aligns to 20:329/332 of 6ya4A
6y9uA Crystal structure of pnra from s. Pneumoniae in complex with adenosine (see paper)
34% identity, 89% coverage: 23:317/331 of query aligns to 20:329/332 of 6y9uA
4pevA Crystal structure of abc transporter system solute-binding proteins from aeropyrum pernix k1
36% identity, 73% coverage: 27:268/331 of query aligns to 6:263/370 of 4pevA
6shuA Borrelia burgdorferi bmpd nucleoside binding protein bound to adenosine (see paper)
30% identity, 91% coverage: 26:325/331 of query aligns to 8:311/316 of 6shuA
3s99A Crystal structure of a basic membrane lipoprotein from brucella melitensis, iodide soak
29% identity, 76% coverage: 67:316/331 of query aligns to 48:289/330 of 3s99A
Sites not aligning to the query:
6piiC The evolving story of atzt, a periplasmic binding protein (see paper)
29% identity, 56% coverage: 67:250/331 of query aligns to 49:226/331 of 6piiC
Sites not aligning to the query:
6pi6A The evolving story of atzt, a periplasmic binding protein (see paper)
29% identity, 56% coverage: 67:250/331 of query aligns to 49:226/333 of 6pi6A
Sites not aligning to the query:
6piiA The evolving story of atzt, a periplasmic binding protein (see paper)
29% identity, 56% coverage: 67:250/331 of query aligns to 52:229/336 of 6piiA
Sites not aligning to the query:
4iilA Crystal structure of rfua (tp0298) of t. Pallidum bound to riboflavin (see paper)
25% identity, 75% coverage: 69:317/331 of query aligns to 55:313/314 of 4iilA
Sites not aligning to the query:
Q56328 ABC transporter riboflavin-binding protein RfuA; Membrane lipoprotein TpN38(b) from Treponema pallidum (strain Nichols) (see paper)
25% identity, 75% coverage: 69:317/331 of query aligns to 82:340/343 of Q56328
Sites not aligning to the query:
>GFF386 FitnessBrowser__Phaeo:GFF386
MTLMKSLMSAAAAVALTAGAAMAEPALIFDLGGKFDKSFNEAAFAGAQRWAEETGESFRE
IELQSEAQREQALRRFAEAGANPIVMAGFAFADALGQVAADYPDTKFVIIDMVVDAPNVR
SVVFNEHEGSYLVGMLAAKASKSGTVGFIGGMDIPLIRKFACGYAEGVKAANPDATVIAN
MTGTTPAAWNDPVKGSELTKAQISQGADVVYAAAGGTGVGVLQTAADEGILSIGVDSNQN
HLHPGKVLTSMMKRVDNAVFEAFSDGTELETGFSVMGLSNGGVGFAVDDNNASLITEEMT
AATDEAAAKIATGEITVHDYMSDDSCPALSF
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory