Comparing GFF44 FitnessBrowser__Phaeo:GFF44 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 8 hits to proteins with known functional sites (download)
4aq6D Substrate bound homogentisate 1,2-dioxygenase (see paper)
51% identity, 95% coverage: 19:447/453 of query aligns to 1:423/427 of 4aq6D
Q88E47 Homogentisate 1,2-dioxygenase; HGDO; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase; EC 1.13.11.5 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
51% identity, 95% coverage: 19:447/453 of query aligns to 7:429/433 of Q88E47
3zdsA Structure of homogentisate 1,2-dioxygenase in complex with reaction intermediates of homogentisate with oxygen. (see paper)
52% identity, 94% coverage: 23:447/453 of query aligns to 3:421/425 of 3zdsA
3zdsF Structure of homogentisate 1,2-dioxygenase in complex with reaction intermediates of homogentisate with oxygen. (see paper)
52% identity, 94% coverage: 23:447/453 of query aligns to 4:422/426 of 3zdsF
3zdsC Structure of homogentisate 1,2-dioxygenase in complex with reaction intermediates of homogentisate with oxygen. (see paper)
52% identity, 94% coverage: 23:447/453 of query aligns to 4:422/426 of 3zdsC
Q9Y041 Homogentisate 1,2-dioxygenase; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase; EC 1.13.11.5 from Caenorhabditis elegans (see paper)
51% identity, 94% coverage: 23:446/453 of query aligns to 9:433/437 of Q9Y041
Q93099 Homogentisate 1,2-dioxygenase; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase; EC 1.13.11.5 from Homo sapiens (Human) (see 13 papers)
46% identity, 94% coverage: 23:446/453 of query aligns to 6:434/445 of Q93099
1ey2A Human homogentisate dioxygenase with fe(ii) (see paper)
46% identity, 91% coverage: 23:435/453 of query aligns to 5:413/419 of 1ey2A
>GFF44 FitnessBrowser__Phaeo:GFF44
MNHEVDAHEMIQAPSPAGPHTGYMPGFGNDFETEALPGALPQGMNSPQKCNYGLYGEQLS
GTAFTAPSHQNERTWCYRIRPSVKHSHRYTKIDLPYWKSAPNVDPDVISLGQYRWDPVPH
GTEGLTWLTGMRTMTTAGDVNTQVGMASHIYLVTDSMMDSYFYSADSELLVVPQEGRLRF
ATELGIIDIEPQEIAIIPRGLVYRVEVLDGPCRGFVCENYGQKFELPGRGPIGANCMANP
RDFKAPVAAFEDRETPSTVTIKWCGQFHETKIGHSPLDVVAWHGNYTPVKYDLRTYCPVG
AILFDHPDPSIFTVLTAPSGQPGTANIDFVLFRERWMVAEDTFRPPWYHKNIMSELMGNI
YGQYDAKPQGFVPGGVSLHNMMLPHGPDRNAFEGASNADLGPEKLDNTMSFMFETRFPQH
LTPFAANEAPLQDDYIDCWADIEKKFDGTPGKK
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory