Comparing GFF4494 PS417_23000 PTS N-acetyl-D-glucosamine transporter to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 4 hits to proteins with known functional sites (download)
P09323 PTS system N-acetylglucosamine-specific EIICBA component; EIICBA-Nag; EII-Nag; EC 2.7.1.193 from Escherichia coli (strain K12) (see paper)
53% identity, 81% coverage: 9:469/568 of query aligns to 7:471/648 of P09323
Sites not aligning to the query:
P69786 PTS system glucose-specific EIICB component; EIICB-Glc; EII-Glc; EC 2.7.1.199 from Escherichia coli (strain K12) (see 5 papers)
42% identity, 80% coverage: 1:456/568 of query aligns to 1:470/477 of P69786
6bvgA Crystal structure of bcmalt t280c-e54c crosslinked by divalent mercury (see paper)
32% identity, 63% coverage: 10:369/568 of query aligns to 6:442/447 of 6bvgA
1o2fB Complex of enzyme iiaglc and iibglc phosphocarrier protein hpr from escherichia coli nmr, restrained regularized mean structure (see paper)
38% identity, 13% coverage: 384:456/568 of query aligns to 1:71/77 of 1o2fB
>GFF4494 PS417_23000 PTS N-acetyl-D-glucosamine transporter
MYQHFIEGLQRLGRALMLPIAILPIAGLLLRLGDTDLLNIAVMHDAGQAIFANLALIFAI
GIAVGFARDNNGTAGLAGAIGYLVMVSTLKVMDTSINMGMLAGIASGLMAGGLYNRFKDI
KLPEYLAFFGGRRFVPIVTGFSAVGLGVIFGLIWPPIQHGINSFGVLLMESGSLGAFVFG
VFNRLLIVTGLHHILNNMAWFVFGSFTDPVTGAVVTGDLTRYFAGDPKGGQFMTGMFPVM
LFGLPAACLAMYRNALPERRKVMGGIFLSMALTSFLTGVTEPIEFAFMFLAPFLYLIHAV
LTGLSMAVTNMLNIHLGFTFSGGFIDMVLGWGKSTNGWLVFPVGLAYALIYYSVFNYCIR
HFNLKTPGREDTQVVQAEAMSDNQRATAYIQALGGAQNLLSVGACTTRLRLDMVDRNKAV
DAELKALGAMAVVRPGNGGSLQVVVGPMADSIADEIRLAMPGFVAAAPVVVAPVEKPVAV
NVQEAEKWLNALGGRGNVRQLEAVAMTRLRVELGDDSGLSEADLTALGCQGVSQLESGVW
HLLIGDKATGLGEALERLVGAQQIGASA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory