Comparing GFF5115 FitnessBrowser__WCS417:GFF5115 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 15 hits to proteins with known functional sites (download)
O50584 Low specificity L-threonine aldolase; Low specificity L-TA; EC 4.1.2.48 from Pseudomonas sp. (strain NCIMB 10558) (see paper)
90% identity, 100% coverage: 1:346/346 of query aligns to 1:346/346 of O50584
5vyeB Crystal structure of l-threonine aldolase from pseudomonas putida
87% identity, 99% coverage: 3:346/346 of query aligns to 1:344/344 of 5vyeB
1v72A Crystal structure of phenylserine aldolase from pseudomonas putida
46% identity, 97% coverage: 8:341/346 of query aligns to 7:342/345 of 1v72A
O07051 L-allo-threonine aldolase; L-allo-TA; L-allo-threonine acetaldehyde-lyase; EC 4.1.2.49 from Aeromonas jandaei (see paper)
27% identity, 80% coverage: 59:336/346 of query aligns to 55:328/338 of O07051
Sites not aligning to the query:
3wgbD Crystal structure of aeromonas jandaei l-allo-threonine aldolase (see paper)
30% identity, 73% coverage: 59:311/346 of query aligns to 53:298/324 of 3wgbD
Sites not aligning to the query:
3wgcB Aeromonas jandaei l-allo-threonine aldolase h128y/s292r double mutant (see paper)
26% identity, 80% coverage: 59:336/346 of query aligns to 54:325/333 of 3wgcB
Sites not aligning to the query:
1jg8D Crystal structure of threonine aldolase (low-specificity)
28% identity, 56% coverage: 10:203/346 of query aligns to 7:198/344 of 1jg8D
Sites not aligning to the query:
1lw5B X-ray structure of l-threonine aldolase (low-specificity) in complex with glycine (see paper)
27% identity, 56% coverage: 10:203/346 of query aligns to 6:197/343 of 1lw5B
Sites not aligning to the query:
1lw4B X-ray structure of l-threonine aldolase (low-specificity) in complex with l-allo-threonine (see paper)
27% identity, 56% coverage: 10:203/346 of query aligns to 6:197/343 of 1lw4B
Sites not aligning to the query:
3wlxA Crystal structure of low-specificity l-threonine aldolase from escherichia coli
24% identity, 89% coverage: 35:341/346 of query aligns to 30:328/331 of 3wlxA
Sites not aligning to the query:
4rjyA Crystal structure of e. Coli l-threonine aldolase in complex with a non-covalently uncleaved bound l-serine substrate (see paper)
26% identity, 46% coverage: 35:193/346 of query aligns to 30:185/332 of 4rjyA
Sites not aligning to the query:
4lnlA Structure of escherichia coli threonine aldolase in complex with allo- thr (see paper)
26% identity, 46% coverage: 35:193/346 of query aligns to 30:185/332 of 4lnlA
Sites not aligning to the query:
4lnjA Structure of escherichia coli threonine aldolase in unliganded form (see paper)
26% identity, 46% coverage: 35:193/346 of query aligns to 30:185/332 of 4lnjA
Sites not aligning to the query:
4lnmA Structure of escherichia coli threonine aldolase in complex with serine (see paper)
26% identity, 46% coverage: 35:193/346 of query aligns to 30:185/331 of 4lnmA
Sites not aligning to the query:
Q8RXU4 Low-specificity L-threonine aldolase 1; Threonine aldolase 1; EC 4.1.2.48 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
24% identity, 73% coverage: 59:310/346 of query aligns to 57:307/358 of Q8RXU4
>GFF5115 FitnessBrowser__WCS417:GFF5115
MTDKSQQFASDNYSGICPEAWAAMEQANQGHQRAYGDDEWTHRAADGFRNLFETDCEVFF
AFNGTAANSLALSSLCQSYHSVICSETAHVETDECGAPEFFSNGSKLLTARTENGKLTPE
SIREIALKRQDIHYPKPRVVTLTQATEVGSVYTPDEIRAISATCKELGLNLHMDGARFSN
ACAFLGCSPADLTWKAGVDVLCFGGTKNGMAVGEAILFFNHKLAEDFDYRCKQAGQLASK
MRFLSAPWVGLLENDAWLKHARHANHCAQLLSSLVADIPGVELMFPVQANGVFLQLSEPA
IAALTAKGWRFYTFIGKGGARFMCAWDTEEERVRELAADIRKVMEA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory