Comparing GFF5184 FitnessBrowser__WCS417:GFF5184 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
2vhaA Debp (see paper)
53% identity, 90% coverage: 24:294/300 of query aligns to 1:271/276 of 2vhaA
2ia4B Crystal structure of novel amino acid binding protein from shigella flexneri
53% identity, 90% coverage: 24:294/300 of query aligns to 2:272/278 of 2ia4B
8ovoA X-ray structure of the sf-iglusnfr-s72a in complex with l-aspartate
52% identity, 81% coverage: 29:272/300 of query aligns to 5:247/503 of 8ovoA
5eyfB Crystal structure of solute-binding protein from enterococcus faecium with bound glutamate
30% identity, 80% coverage: 30:268/300 of query aligns to 6:234/243 of 5eyfB
4zv2A An ancestral arginine-binding protein bound to glutamine (see paper)
31% identity, 73% coverage: 49:268/300 of query aligns to 16:223/225 of 4zv2A
Sites not aligning to the query:
4zv1A An ancestral arginine-binding protein bound to arginine (see paper)
30% identity, 73% coverage: 49:268/300 of query aligns to 16:225/226 of 4zv1A
Sites not aligning to the query:
6h20A Glnh bound to asn, mycobacterium tuberculosis (see paper)
25% identity, 86% coverage: 18:274/300 of query aligns to 32:281/287 of 6h20A
6h1uA Glnh bound to asp, mycobacterium tuberculosis (see paper)
25% identity, 86% coverage: 18:274/300 of query aligns to 32:281/287 of 6h1uA
6h2tA Glnh bound to glu, mycobacterium tuberculosis (see paper)
25% identity, 86% coverage: 18:274/300 of query aligns to 33:282/288 of 6h2tA
5t0wA Crystal structure of the ancestral amino acid-binding protein anccdt- 1, a precursor of cyclohexadienyl dehydratase
29% identity, 80% coverage: 29:269/300 of query aligns to 2:229/229 of 5t0wA
6svfA Crystal structure of the p235gk mutant of argbp from t. Maritima (see paper)
29% identity, 73% coverage: 49:268/300 of query aligns to 22:227/229 of 6svfA
Sites not aligning to the query:
4ohnA Crystal structure of an abc uptake transporter substrate binding protein from streptococcus pneumoniae with bound histidine
27% identity, 81% coverage: 32:275/300 of query aligns to 8:246/246 of 4ohnA
2yjpA Crystal structure of the solute receptors for l-cysteine of neisseria gonorrhoeae (see paper)
26% identity, 80% coverage: 28:266/300 of query aligns to 2:229/247 of 2yjpA
4ymxA Crystal structure of the substrate binding protein of an amino acid abc transporter (see paper)
26% identity, 74% coverage: 49:269/300 of query aligns to 13:223/224 of 4ymxA
Sites not aligning to the query:
4z9nB Abc transporter / periplasmic binding protein from brucella ovis with glutathione bound
28% identity, 60% coverage: 86:265/300 of query aligns to 59:241/324 of 4z9nB
Sites not aligning to the query:
2v25A Structure of the campylobacter jejuni antigen peb1a, an aspartate and glutamate receptor with bound aspartate (see paper)
23% identity, 80% coverage: 28:267/300 of query aligns to 1:229/231 of 2v25A
1xt8B Crystal structure of cysteine-binding protein from campylobacter jejuni at 2.0 a resolution (see paper)
24% identity, 75% coverage: 28:251/300 of query aligns to 5:217/251 of 1xt8B
2pyyB Crystal structure of the glur0 ligand-binding core from nostoc punctiforme in complex with (l)-glutamate (see paper)
28% identity, 69% coverage: 62:269/300 of query aligns to 19:211/217 of 2pyyB
Sites not aligning to the query:
2y7iA Structural basis for high arginine specificity in salmonella typhimurium periplasmic binding protein stm4351. (see paper)
22% identity, 78% coverage: 35:268/300 of query aligns to 4:227/228 of 2y7iA
P02911 Lysine/arginine/ornithine-binding periplasmic protein; LAO-binding protein from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
24% identity, 90% coverage: 1:269/300 of query aligns to 1:254/260 of P02911
>GFF5184 FitnessBrowser__WCS417:GFF5184
MKKILLTGCTLGLLLGAQAHANQAPLDGTLGKIASAKSITLGYRDASVPFSYVGDNSGKP
MGYSVELASKIVERIQQKTGVATLNVKYNLVTSQTRIPLVQNGTVDLECGSTGVTAERQK
QVAFSYGFIYVKGQLLTAKDSGIKGFPDLAGKNVVTTAGTTNERFLKSYNAEHKTNMFVI
SAKDHGEAFKMLETGRAAAFYMDDALLYGERAKAKDPHNWVVVGEEQSREIYSCMLRKDD
PQFLAVVNETLGDLYRSGEINGIYQRWFESPIPPKGLNLEFPMTRELKAIIAKPISDPVE
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory