Comparing GFF723 PGA1_c07380 dihydroxy-acid dehydratase IlvD to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 12 hits to proteins with known functional sites (download)
8ej0A Crystal structure of fe-s cluster-dependent dehydratase from paralcaligenes ureilyticus in complex with mg
61% identity, 99% coverage: 5:571/571 of query aligns to 2:568/568 of 8ej0A
8epzA Crystal structure of fe-s cluster-dependent dehydratase from paralcaligenes ureilyticus in complex with mn
61% identity, 99% coverage: 5:571/571 of query aligns to 3:569/569 of 8epzA
B5ZZ34 L-arabinonate dehydratase; ArDHT; D-fuconate dehydratase; Galactonate dehydratase; L-arabonate dehydratase; EC 4.2.1.25; EC 4.2.1.67; EC 4.2.1.6 from Rhizobium leguminosarum bv. trifolii (strain WSM2304) (see 2 papers)
58% identity, 99% coverage: 6:571/571 of query aligns to 12:579/579 of B5ZZ34
Q1JUQ1 L-arabonate dehydratase; L-arabinonate dehydratase; EC 4.2.1.25 from Azospirillum brasilense (see paper)
58% identity, 100% coverage: 2:571/571 of query aligns to 4:583/583 of Q1JUQ1
5j85A Ser480ala mutant of l-arabinonate dehydratase (see paper)
57% identity, 99% coverage: 6:571/571 of query aligns to 9:576/576 of 5j85A
7m3kA Crystal structure of galactonate dehydratase from brucella melitensis biovar abortus 2308
47% identity, 92% coverage: 6:528/571 of query aligns to 3:540/587 of 7m3kA
Q9A9Z2 D-xylonate dehydratase; XyDHT; Gluconate dehydratase; EC 4.2.1.82; EC 4.2.1.39 from Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus) (see 2 papers)
40% identity, 97% coverage: 6:559/571 of query aligns to 14:581/595 of Q9A9Z2
5oynA Crystal structure of d-xylonate dehydratase in holo-form (see paper)
40% identity, 97% coverage: 6:559/571 of query aligns to 8:575/589 of 5oynA
P9WKJ5 Dihydroxy-acid dehydratase; DAD; EC 4.2.1.9 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
39% identity, 93% coverage: 22:553/571 of query aligns to 34:572/575 of P9WKJ5
6ovtA Crystal structure of ilvd from mycobacterium tuberculosis (see paper)
39% identity, 93% coverage: 22:553/571 of query aligns to 21:559/562 of 6ovtA
8hs0A The mutant structure of dhad v178w
36% identity, 91% coverage: 38:556/571 of query aligns to 47:569/570 of 8hs0A
Q9LIR4 Dihydroxy-acid dehydratase, chloroplastic; AthDHAD; DAD; EC 4.2.1.9 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
36% identity, 91% coverage: 38:556/571 of query aligns to 85:607/608 of Q9LIR4
>GFF723 PGA1_c07380 dihydroxy-acid dehydratase IlvD
MTKDRRNRAWYGKLDKDGFIHRSWMKNQGFPDHAFDGRPIIGICNTWSELTPCNSGLRDL
AEGVKRGVWEAGGFPVEFPVMSLGETQMKPTAMLFRNLLAMDVEESIRAYGIDGVVLLGG
CDKTTPGQLMGAASVDLPAIVVSSGPMLNGKWQGKDIGSGTDVWKFSEAVRAGEMTLQDF
MAAESGMSRSKGVCMTMGTASTMASLVEAMGMSLPTNAALPAVDARRMALAHLTGKRIVE
MVEEDIKPSDVLTREAFVNAIMANAAVGGSTNAVVHLLALAGRVGAELSLDDFDLGSDIP
LLVNCMPSGKYLMEDFCYAGGMPVVLKQLADNGHLRSNTTVLGGDILAYAEGAECFNDDV
IKSFDEPVKPAAGLRVLRGNLAPNGAIVKPSAATDHLLEHEGVAHVFETIEDMKANIDRD
DLPVTKDSILVLKGVGPKGYPGMPEVGNMPIPRKLVREGVRDMIRISDGRMSGTAFGTVI
LHVSPESQAGGPLGLVQTGDRIRVSAKNGTLDLLVSEEELTARREAWQPEPLHYTRGYAK
LYVDSVLQAEKGADLDFLVGKDTRPVTRESH
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory