Comparing GFF767 FitnessBrowser__Phaeo:GFF767 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3fcrA Crystal structure of putative aminotransferase (yp_614685.1) from silicibacter sp. Tm1040 at 1.80 a resolution
84% identity, 100% coverage: 1:457/457 of query aligns to 2:458/458 of 3fcrA
3gjuA Crystal structure of a putative aminotransferase (mll7127) from mesorhizobium loti maff303099 at 1.55 a resolution
72% identity, 99% coverage: 3:456/457 of query aligns to 5:457/458 of 3gjuA
5kr6B Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
64% identity, 100% coverage: 1:455/457 of query aligns to 3:456/460 of 5kr6B
5kr3A Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
63% identity, 100% coverage: 1:455/457 of query aligns to 2:453/458 of 5kr3A
5kr5A Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
60% identity, 99% coverage: 5:455/457 of query aligns to 3:452/455 of 5kr5A
5kquC Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
60% identity, 100% coverage: 1:457/457 of query aligns to 1:456/459 of 5kquC
5ghgB Transaminase w58l with smba
43% identity, 91% coverage: 34:447/457 of query aligns to 29:419/433 of 5ghgB
Sites not aligning to the query:
D6R3B6 Vanillin aminotransferase; Putative aminotransferase; pAMT; EC 2.6.1.119 from Capsicum frutescens (Cayenne pepper) (Tabasco pepper) (see paper)
39% identity, 94% coverage: 22:452/457 of query aligns to 14:444/459 of D6R3B6
7qx3A Structure of the transaminase tr2e2 with eos (see paper)
41% identity, 92% coverage: 33:452/457 of query aligns to 2:414/422 of 7qx3A
Q94CE5 Gamma-aminobutyrate transaminase POP2, mitochondrial; AtGABA-T; Gamma-aminobutyric acid aminotransferase 1; Protein HEXENAL RESPONSE 1; Protein POLLEN-PISTIL INCOMPATIBILITY 2; AtPOP2; EC 2.6.1.96 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
38% identity, 95% coverage: 22:455/457 of query aligns to 56:491/504 of Q94CE5
7qx0B Transaminase structure of plurienzyme (tr2e2) in complex with plp (see paper)
39% identity, 97% coverage: 11:452/457 of query aligns to 9:435/443 of 7qx0B
6g4dB Crystal structure of the omega transaminase from pseudomonas jessenii in complex with plp (see paper)
39% identity, 92% coverage: 34:452/457 of query aligns to 28:442/453 of 6g4dB
Sites not aligning to the query:
6g4fA Crystal structure of the omega transaminase from pseudomonas jessenii in complex with pmp (see paper)
39% identity, 92% coverage: 34:452/457 of query aligns to 28:442/451 of 6g4fA
Sites not aligning to the query:
6g4eA Crystal structure of the omega transaminase from pseudomonas jessenii in complex with plp and 6-aminohexanoate (6-aca) (see paper)
39% identity, 92% coverage: 34:452/457 of query aligns to 28:442/451 of 6g4eA
Sites not aligning to the query:
6io1B Crystal structure of a novel thermostable (s)-enantioselective omega- transaminase from thermomicrobium roseum (see paper)
41% identity, 96% coverage: 16:456/457 of query aligns to 17:447/448 of 6io1B
6gwiB The crystal structure of halomonas elongata amino-transferase (see paper)
41% identity, 97% coverage: 11:452/457 of query aligns to 10:442/450 of 6gwiB
7ypmA Crystal structure of transaminase cc1012 complexed with plp and l- alanine (see paper)
40% identity, 92% coverage: 33:452/457 of query aligns to 31:444/454 of 7ypmA
7ypnD Crystal structure of transaminase cc1012 mutant m9 complexed with plp (see paper)
40% identity, 92% coverage: 33:452/457 of query aligns to 31:444/455 of 7ypnD
7q9xAAA Probable aminotransferase
37% identity, 98% coverage: 4:452/457 of query aligns to 3:442/455 of 7q9xAAA
4a6tC Crystal structure of the omega transaminase from chromobacterium violaceum in complex with plp (see paper)
37% identity, 98% coverage: 4:452/457 of query aligns to 3:442/455 of 4a6tC
>GFF767 FitnessBrowser__Phaeo:GFF767
MLRNDQLDQWDRDSFFHPSTHLAEFARGNLPQRVVTGGTGCHIEDRDGNRMLDAFAGLYC
VNVGYGRPEIAEAIADQARELAYYHSYVGHGTEASITLAKMIMDRAPDHMSKVYFGLSGS
DANETNIKLIWYYNNILGRPEKKKIISRWRGYHGSGLMTGSLTGLELFHNKFDLPLAQVV
HTESPYYFRREDLSQSEADFVAHCVAELEALIAREGADTIAAFIGEPVLGTGGIVPPPAG
YWPAIQAVLERHDILLVADEVVTGFGRLGTMFGSDHYGMRPDLITIAKGLTSAYAPLSGS
IVSDKMWQVLERGTDENGPIGHGWTYSAHPIGAAAGVANLKLIDQLGLVENAGAIGAYLN
DEMRKALGDHPNVGDLRGEGMLCAVEFVADRDDRRFFDASDKIGPQIAAKLLEQDSVIAR
AMPQGDILGFAPPFCLTRDEADRVVAATHRAVTAVLG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory