Comparing GFF786 FitnessBrowser__Marino:GFF786 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 8 hits to proteins with known functional sites (download)
4f4fA X-ray crystal structure of plp bound threonine synthase from brucella melitensis
54% identity, 100% coverage: 1:464/466 of query aligns to 2:463/464 of 4f4fA
1kl7A Crystal structure of threonine synthase from yeast (see paper)
44% identity, 91% coverage: 3:426/466 of query aligns to 7:464/509 of 1kl7A
Q42598 Threonine synthase; TS; EC 4.2.3.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
44% identity, 90% coverage: 1:420/466 of query aligns to 5:459/514 of Q42598
8g1yA Crystal structure of the threonine synthase from streptococcus pneumoniae in complex with pyridoxal 5-phosphate.
36% identity, 91% coverage: 1:423/466 of query aligns to 5:439/496 of 8g1yA
1vb3A Crystal structure of threonine synthase from escherichia coli
33% identity, 94% coverage: 1:437/466 of query aligns to 1:402/428 of 1vb3A
6nmxA Threonine synthase from bacillus subtilis atcc 6633 with plp and appa (see paper)
27% identity, 41% coverage: 71:263/466 of query aligns to 12:193/350 of 6nmxA
Sites not aligning to the query:
6cgqB Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala (see paper)
27% identity, 41% coverage: 71:263/466 of query aligns to 10:191/345 of 6cgqB
Sites not aligning to the query:
6cgqA Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala (see paper)
27% identity, 41% coverage: 71:263/466 of query aligns to 8:183/339 of 6cgqA
Sites not aligning to the query:
>GFF786 FitnessBrowser__Marino:GFF786
MRYISTRGEAPALGFEDVLLTGLATDGGLYVPESLPHFDLEEIRSWRGLSYSELAFNVMY
PFVDDAIPADDFRKMLDETYSVFAHKAVAPLVQLDTNEWVMELFRGPTLAFKDFALQLLG
RLLDYVLEKRKQHVVIMGATSGDTGSAAIEGCRRCEHVDIFILHPYQRVSEVQRRQMTTV
QGENIHNIAVRGNFDDCQRMVKESFGNQSFLGGKTQLAAVNSINWARIMAQIVYYFHASL
ALGGPDRSMAFSVPTGNFGDIFAGYLAKKMGLPISQLVIATNRNDILHRFMSGNKYEQHQ
LEHTLSPSMDIMVSSNFERLLFDLHGRDGLAVKTLLENAAKGPVSIEDYRWKHARKLFDS
DAVDDKATCDTIREIYEQNEYLLDPHTAIGVRAARNCRRDQAVPMITLGTAHPAKFPDAV
AESGVSVEPPLPAHMADLFEREERYTVLDNNIDGVQAFIAKHWKNA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory