Comparing GFF835 FitnessBrowser__Marino:GFF835 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
1o4sB Crystal structure of aspartate aminotransferase (tm1255) from thermotoga maritima at 1.90 a resolution (see paper)
37% identity, 84% coverage: 57:407/416 of query aligns to 37:378/384 of 1o4sB
1gdeA Crystal structure of pyrococcus protein a-1 e-form (see paper)
34% identity, 89% coverage: 38:407/416 of query aligns to 6:378/388 of 1gdeA
1gd9A Crystall structure of pyrococcus protein-a1 (see paper)
34% identity, 89% coverage: 38:407/416 of query aligns to 6:378/388 of 1gd9A
1gc4A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with aspartate (see paper)
32% identity, 84% coverage: 58:406/416 of query aligns to 32:377/382 of 1gc4A
1gc3A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with tryptophan (see paper)
32% identity, 84% coverage: 58:406/416 of query aligns to 32:377/382 of 1gc3A
Sites not aligning to the query:
1b5oA Thermus thermophilus aspartate aminotransferase single mutant 1 (see paper)
32% identity, 84% coverage: 58:406/416 of query aligns to 32:377/382 of 1b5oA
Q56232 Aspartate/prephenate aminotransferase; AspAT / PAT; Transaminase A; EC 2.6.1.1; EC 2.6.1.78 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 3 papers)
32% identity, 84% coverage: 58:406/416 of query aligns to 32:377/385 of Q56232
Sites not aligning to the query:
1bkgA Aspartate aminotransferase from thermus thermophilus with maleate (see paper)
32% identity, 84% coverage: 58:406/416 of query aligns to 32:377/382 of 1bkgA
1bjwA Aspartate aminotransferase from thermus thermophilus (see paper)
32% identity, 84% coverage: 58:406/416 of query aligns to 32:377/382 of 1bjwA
5wmiA Arabidopsis thaliana prephenate aminotransferase mutant- t84v (see paper)
31% identity, 90% coverage: 33:407/416 of query aligns to 2:392/402 of 5wmiA
5wmhA Arabidopsis thaliana prephenate aminotransferase (see paper)
31% identity, 90% coverage: 33:407/416 of query aligns to 1:392/399 of 5wmhA
1j32A Aspartate aminotransferase from phormidium lapideum
30% identity, 86% coverage: 52:407/416 of query aligns to 25:380/388 of 1j32A
5wmlA Arabidopsis thaliana prephenate aminotransferase mutant- k306a (see paper)
31% identity, 90% coverage: 33:407/416 of query aligns to 2:393/404 of 5wmlA
Q58097 (5-formylfuran-3-yl)methyl phosphate transaminase; 4-HFC-P:alanine aminotransferase; EC 2.6.1.108 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
29% identity, 87% coverage: 52:413/416 of query aligns to 24:370/370 of Q58097
6f77A Crystal structure of the prephenate aminotransferase from rhizobium meliloti (see paper)
30% identity, 87% coverage: 47:407/416 of query aligns to 20:391/399 of 6f77A
Q02635 Aspartate/prephenate aminotransferase; AspAT / PAT; Transaminase A; EC 2.6.1.1; EC 2.6.1.79 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
30% identity, 87% coverage: 47:407/416 of query aligns to 21:392/400 of Q02635
Sites not aligning to the query:
1xi9C Alanine aminotransferase from pyrococcus furiosus pfu-1397077-001
32% identity, 86% coverage: 59:414/416 of query aligns to 30:393/393 of 1xi9C
P14909 Aspartate aminotransferase; AspAT; Transaminase A; EC 2.6.1.1 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
30% identity, 87% coverage: 46:407/416 of query aligns to 25:391/402 of P14909
Sites not aligning to the query:
P58350 Aspartate aminotransferase; AAT; AspAT; Putative 2-aminoadipate transaminase; Transaminase A; EC 2.6.1.1; EC 2.6.1.39 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
29% identity, 91% coverage: 31:407/416 of query aligns to 9:402/410 of P58350
8wkjA The crystal structure of aspartate aminotransferases lpg0070 from legionella pneumophila (see paper)
28% identity, 84% coverage: 58:407/416 of query aligns to 32:386/391 of 8wkjA
>GFF835 FitnessBrowser__Marino:GFF835
MPRLQEVFMAEAANKETGQEKPRRVKYRKTKASWNPAMQAIPVPGIRRMVNMAATMKDVI
HLSIGQPDLPTPKHVIDAYIDALNAGQTGYTMDAGLPELLVALRDYYGKRYNRKLTRDNI
LITSGATEAMYLAISATSAPGRQFIVTDPSFLLYAPLIRMNGGEVKFVQTRAENNHQLDP
DEVIKAMGPRTYALILNNPNNPTGAVYPRSTVETILEECAYRGIQVYADEVYDHLIFDDE
DFASVLNCSMDLDNIMCISSFSKTYSMAGLRVGWVIASQAAIKSLRRFHMFTTSVANTPS
QFAGVAALTGDQQCVRDMVDIYRERRDKVVELVDQTPYMTGYKPGGAFFAFPDLPPHVDG
SDLALRMLKETGVCMVPGDAFGEGCTNAVRISFSTTCEKLEEAFDRVIPWMAKQQF
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory