Comparing GFF850 FitnessBrowser__psRCH2:GFF850 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 4 hits to proteins with known functional sites (download)
P02916 Maltose/maltodextrin transport system permease protein MalF from Escherichia coli (strain K12) (see 4 papers)
51% identity, 91% coverage: 47:520/521 of query aligns to 34:512/514 of P02916
4ki0F Crystal structure of the maltose-binding protein/maltose transporter complex in an outward-facing conformation bound to maltohexaose (see paper)
51% identity, 90% coverage: 47:513/521 of query aligns to 23:490/490 of 4ki0F
7cagA Mycobacterium smegmatis lpqy-sugabc complex in the catalytic intermediate state (see paper)
28% identity, 49% coverage: 262:516/521 of query aligns to 45:278/285 of 7cagA
P94529 Arabinooligosaccharides transport system permease protein AraP from Bacillus subtilis (strain 168) (see paper)
26% identity, 33% coverage: 262:435/521 of query aligns to 64:232/313 of P94529
>GFF850 FitnessBrowser__psRCH2:GFF850
MNARAELPSPAMTRPTSWGLPRFLTTGVRWLLWLAFNALSLYLVVALYVQKQMAFALLGL
VVTGIASYLFINRRMYAQRYIFPSVAGMLVFVIFPLLYTVGIGFTNYSGTNLLSQAQVER
YHLSQTYLAGERFRFTLHQSPDGERLRVDKGELGVFVSPPLTGEPDPEAPLSLLPAESVE
GLGEALALREVIQRRKVLEQWVMQAPDGSLLRLYGLREVAAVEPQYRQDGPGVLVETRTG
ARLTADMERGFYVDETGKAVPPGFTVFTGFANFSRVLTEPSIREPFMQIFAWTFAFAGLT
VVFTLAVGLVLASLLQWELVRGKAFYRLMLILPYAVPGFISILVFRGLFNQNFGEINLLL
EGLFGIRPDWFSDPSLARTMILIVNTWLGYPYMLLLCMGLLQAIPRDQYEASAIDGASPL
DNLLRITLPQLIKPLMPLLIACFAFNFNNFVLITLLTRGGPDIIGATTPAGTTDLLVSYT
YRIAFQDSGQDFALAAAIATMIFILVGAMALLNLKLSKVKV
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory