Comparing Ga0059261_0263 FitnessBrowser__Korea:Ga0059261_0263 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 10 hits to proteins with known functional sites (download)
3k6mC Dynamic domains of succinyl-coa:3-ketoacid-coenzyme a transferase from pig heart. (see paper)
55% identity, 96% coverage: 5:212/216 of query aligns to 249:456/466 of 3k6mC
Sites not aligning to the query:
Q29551 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; SCOT; 3-oxoacid CoA-transferase 1; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; SCOT-s; Succinate-coenzyme A transferase; Succinyl-CoA:3-oxoacid CoA transferase; EC 2.8.3.5 from Sus scrofa (Pig) (see 3 papers)
55% identity, 96% coverage: 5:212/216 of query aligns to 302:509/520 of Q29551
Sites not aligning to the query:
1o9lA Succinate:coenzyme-a transferase (pig heart)
55% identity, 96% coverage: 5:212/216 of query aligns to 250:457/468 of 1o9lA
Sites not aligning to the query:
3oxoE Succinyl-coa:3-ketoacid coa transferase from pig heart covalently bound to coa (see paper)
56% identity, 94% coverage: 11:212/216 of query aligns to 251:452/462 of 3oxoE
8i3yD Crystal structure of asct from trypanosoma brucei in complex with succinyl-coa.
55% identity, 95% coverage: 5:210/216 of query aligns to 257:460/471 of 8i3yD
Sites not aligning to the query:
8i40A Crystal structure of asct from trypanosoma brucei in complex with coa.
55% identity, 95% coverage: 5:210/216 of query aligns to 253:456/467 of 8i40A
9ctdB Ctfab f42ts45c mutant co-crystallized with acetyl-coa (see paper)
54% identity, 96% coverage: 5:212/216 of query aligns to 3:207/214 of 9ctdB
8i3yA Crystal structure of asct from trypanosoma brucei in complex with succinyl-coa.
55% identity, 94% coverage: 7:210/216 of query aligns to 249:450/459 of 8i3yA
Sites not aligning to the query:
9cryB Ctfab e46s active site mutant inactive (see paper)
53% identity, 96% coverage: 5:212/216 of query aligns to 3:207/214 of 9cryB
2ahvA Crystal structure of acyl-coa transferase from e. Coli o157:h7 (ydif)- thioester complex with coa- 1 (see paper)
29% identity, 89% coverage: 5:196/216 of query aligns to 278:472/512 of 2ahvA
>Ga0059261_0263 FitnessBrowser__Korea:Ga0059261_0263
MPWTRDEMAARAAKELRDGFYVNLGIGIPTLVANHIPEGVEVTLQSENGMLGIGPFPYEG
EEDPDLINAGKQTISELPQSVYFSSADSFAMIRGGHIDLTVLGAMEVAQNGDIANWMIPG
KMIKGMGGAMDLVAGVKKIIVVMEHNAKDGTPKFIPECTLPLTGKNVVDMIITDLAVFQR
ADHDSPFRLIELAPGVTEEELAAKTTAKYEVALAAA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory