SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing Ga0059261_1585 FitnessBrowser__Korea:Ga0059261_1585 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 1 hits to proteins with known functional sites (download)

Q39232 Sucrose transport protein SUC1; AtSUC1; Sucrose permease 1; Sucrose-proton symporter 1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
30% identity, 29% coverage: 20:161/494 of query aligns to 42:197/513 of Q39232

query
sites
Q39232

G

G

I

V

Q

Q

I

F

G

G

F

W

A

A

L

L

Q

Q

N

L

A

S

N

L

M

L

S

T

R

P

I

Y

F

V

Q

Q

S

L

L

L

G

G

T

I

S

P

I
x
H

D

K

D

W

L

S

P

S

A

L

L

I

W

W

V

L

A

C

A

G

P

P

L

V

T

S

G

G

L

M

L

I

V

V

Q

Q

P

P

V

I

I

V

G

G

H

F

M

H

S

S

D

D

R

R

T

C

W

-

L

R

G

S

R

K

L

F

G

G

R

R

R

R

R

R

P

P

Y

F

F

I

L

A

A

T

G

G

A

A

I

A

L

L

A

V

A

A

L

V

A

A

L

V

F

F

A

L

M

I

P

G

L

Y

A

A

P

A

V

D

L

F

L

G

F

Y

A

K

-

M

-

G

-

D

-

K

-

L

-

E

-

E

-

K

-

V

-

K

-

V

-

R

-

A

-

I

-

G

-

I

-

F

A

A

V

L

M

G

L

F

W

W

V

I

L

L

D

D

A

V

S

A

L

N

N

N

V

T

S

L

M

Q

E

G

P

P

F

C

R

R

A

A

F

F

V

L

G

A

D

D

M

L

L

A

R

A

K

G

D

D

Q

A

H

K

S

R

A

T

G

-

Y

-

A

R

V

V

Q

A

T

N

A

A

F

F

I

F

G

S

A

F

G

F

A

M

V

A

V

V

G

G

S

N

I

V

F

L

P

G

W

Y

A

A

H65 (≠ I43) mutation to C: No sucrose transport activity, high instability.; mutation H->D,G,L,Y: Reduced sucrose transport activity.; mutation to K: Enhanced sucrose transport activity.; mutation to Q: Reduced sensitivity to DEPC.; mutation to R: Enhanced sucrose transport activity, reduced sensitivity to DEPC.; mutation to S: Reduced sucrose transport activity, reduced sensitivity to DEPC.

Query Sequence

>Ga0059261_1585 FitnessBrowser__Korea:Ga0059261_1585
MEKPRQGFWGLFNLSFGFFGIQIGFALQNANMSRIFQSLGTSIDDLPALWVAAPLTGLLV
QPVIGHMSDRTWLGRLGRRRPYFLAGAILAALALFAMPLAPVLLFAAVMLWVLDASLNVS
MEPFRAFVGDMLRKDQHSAGYAVQTAFIGAGAVVGSIFPWALEHLGVSNTAPGGGIPDTV
RYAFWFGGAALFLAVLWTIVSTKEYSPEEMAAFDGPRAETDETAMRALAARSNTSSLIWI
AAGAAVIVAVGRFGLEKEVYLLGGLLAGYGVASLIAVLLARRGSGANMLSHIVGDFAGMP
PLMKKLAVAQFFSWSALFIMWINTTPVVAQYFYRAADAADSRYQEGANWVGVLFTVYNGI
AAVAALTLLPLLASRIGKARTHIVGLVCGAAGFASFFAIRDPHWLILSEIGIGIAWASIL
AMPYAILASSLPQAKLGIYMGLFNVFVVVPQLLVATVMGSIMKRFFPDEPIWTMAFAAVT
LLVAAVAMLRVKEA

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory