Comparing Ga0059261_3183 FitnessBrowser__Korea:Ga0059261_3183 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
6kxhB Alp1u_y247f mutant in complex with fluostatin c (see paper)
37% identity, 40% coverage: 34:155/305 of query aligns to 15:136/294 of 6kxhB
Sites not aligning to the query:
7c4dA Marine microorganism esterase (see paper)
29% identity, 43% coverage: 50:181/305 of query aligns to 5:136/261 of 7c4dA
6eb3A Structural and enzymatic characterization of an esterase from a metagenomic library
30% identity, 68% coverage: 43:248/305 of query aligns to 5:225/265 of 6eb3A
2xuaH Crystal structure of the enol-lactonase from burkholderia xenovorans lb400 (see paper)
34% identity, 37% coverage: 44:155/305 of query aligns to 6:121/261 of 2xuaH
Sites not aligning to the query:
6eb3C Structural and enzymatic characterization of an esterase from a metagenomic library
30% identity, 68% coverage: 43:248/305 of query aligns to 5:222/262 of 6eb3C
6eb3B Structural and enzymatic characterization of an esterase from a metagenomic library
29% identity, 68% coverage: 43:248/305 of query aligns to 5:228/268 of 6eb3B
P80299 Bifunctional epoxide hydrolase 2; EC 3.3.2.10; EC 3.1.3.76 from Rattus norvegicus (Rat) (see paper)
31% identity, 47% coverage: 30:171/305 of query aligns to 228:371/554 of P80299
Sites not aligning to the query:
1ek2A Crystal structure of murine soluble epoxide hydrolase complexed with cdu inhibitor (see paper)
32% identity, 41% coverage: 30:155/305 of query aligns to 171:300/487 of 1ek2A
Sites not aligning to the query:
1ek1A Crystal structure of murine soluble epoxide hydrolase complexed with ciu inhibitor (see paper)
32% identity, 45% coverage: 30:166/305 of query aligns to 174:310/490 of 1ek1A
Sites not aligning to the query:
1cr6B Crystal structure of murine soluble epoxide hydrolase complexed with cpu inhibitor (see paper)
32% identity, 41% coverage: 30:155/305 of query aligns to 225:354/541 of 1cr6B
Sites not aligning to the query:
P34914 Bifunctional epoxide hydrolase 2; EC 3.3.2.10; EC 3.1.3.76 from Mus musculus (Mouse) (see 2 papers)
32% identity, 41% coverage: 30:155/305 of query aligns to 228:357/554 of P34914
Sites not aligning to the query:
A0A126P745 Epoxide hydrolase; BoEH; EC 3.3.2.10 from Bosea sp. (strain PAMC 26642) (see paper)
34% identity, 41% coverage: 37:162/305 of query aligns to 8:130/288 of A0A126P745
Sites not aligning to the query:
4nvrA 2.22 angstrom resolution crystal structure of a putative acyltransferase from salmonella enterica
31% identity, 36% coverage: 46:156/305 of query aligns to 24:139/302 of 4nvrA
Sites not aligning to the query:
5alrA Ligand complex structure of soluble epoxide hydrolase (see paper)
28% identity, 49% coverage: 26:173/305 of query aligns to 222:374/542 of 5alrA
Sites not aligning to the query:
3b12A Crystal structure of the fluoroacetate dehalogenase d104 mutant from burkholderia sp. Fa1 in complex with fluoroacetate (see paper)
31% identity, 38% coverage: 42:156/305 of query aligns to 10:129/294 of 3b12A
Sites not aligning to the query:
5am5A Ligand complex structure of soluble epoxide hydrolase (see paper)
29% identity, 48% coverage: 26:171/305 of query aligns to 222:372/546 of 5am5A
Sites not aligning to the query:
5am4A Ligand complex structure of soluble epoxide hydrolase (see paper)
29% identity, 48% coverage: 26:171/305 of query aligns to 222:372/546 of 5am4A
Sites not aligning to the query:
5am1A Ligand complex structure of soluble epoxide hydrolase (see paper)
29% identity, 48% coverage: 26:171/305 of query aligns to 222:372/546 of 5am1A
Sites not aligning to the query:
5am0A Ligand complex structure of soluble epoxide hydrolase (see paper)
29% identity, 48% coverage: 26:171/305 of query aligns to 222:372/546 of 5am0A
Sites not aligning to the query:
5alzA Ligand complex structure of soluble epoxide hydrolase (see paper)
29% identity, 48% coverage: 26:171/305 of query aligns to 222:372/546 of 5alzA
Sites not aligning to the query:
>Ga0059261_3183 FitnessBrowser__Korea:Ga0059261_3183
MFATIRSHLLLAAAALATPLAAHAQTTPAVAAQPTPVRSGTVEVAGIAYYYEIRGQGEPL
LLLHGGLGSIDMFAPILPALAEGRQVIAVDLQGHGRTPLGTRPIAIEPMGSDMSILLDKL
GYKQVDVMGYSMGAGVAFQLAARHPDRVRRLALVSMTLSTAGIQPEMVPIQRQLTAAMAP
MMKETPMYTGYVARAPKPEDFPRLLDQMGDLMRRDFDWSAQVKALTMPVMLVVGDADMWR
PEGSVEFFKLLGGGQRDGGWQREHVTKHRLAILPGRTHYDIFLAPELVRTVRPFLDGKEG
RVDWQ
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory