SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing Ga0059261_3667 FitnessBrowser__Korea:Ga0059261_3667 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 1 hits to proteins with known functional sites (download)

P68183 Maltose/maltodextrin transport system permease protein MalG from Escherichia coli (strain K12) (see 2 papers)
28% identity, 66% coverage: 13:162/229 of query aligns to 88:229/296 of P68183

query
sites
P68183

S

S

L

V

K

K

V

V

G

A

L

G

V

I

A

S

T

A

V

I

V

G

T

I

L

V

P

A

I

L

A

S

F

T

A

T

L

C

A

A

W

Y

L

A

L

F

A

A

R

R

T

M

R

R

F

F

P

P

G

G

K

K

-

A

I

T

L

L

I

L

D

K

G

G

L

M

V

L

H

I

L

F

P

Q

L

M

V

F

V

-

P

P

P

A

V

V

V

L

T

S

G

-

W

-

L

-

L

L

L

V

L

A

A

L

F

Y

A

A

P

L

A

F

G

D

P

R

V

L

G

G

G

E

W

Y

L

I

E

P

N

-

W

F

F

I

G

G

I

L

S

N

V

T

M

-

F

-

R

-

W

-

T

H

G

G

A

G

A

V

I

I

A

F

A

A

G

Y

V

L

M

G

A

G

L

I

P

A

L

L

M

H

V

V

R

W

A

T

M

I

R

K

L

G

S

Y

I

F

E

E

A

T

V

I

D

D

R

S

R

S

L

L

E

E

N
x
E

A

A

A
|
A

R

A

T

L

L

D

G
|
G

A

A

S

T

R

P

E

W

R

Q

V

A

F

F

R

R

T

L

I

V

T

L

L

L

P
|
P

L

L

A

S

L

V

P

P

G

I

V

L

L

A

A

V

A

V

A

F

V

I

L

L

G

S

F

F

A

I

R

A

A

A

L

I

G

T

E

E

E190 (≠ N123) mutation E->A,C,K,L: Reduction of transport rate.
A192 (= A125) mutation A->D,S,L: Loss of transport and MalK dissociation from the membrane.
G196 (= G129) mutation to A: No effect.; mutation to P: Loss of transport and MalK dissociation from the membrane.
P209 (= P142) mutation to A: No effect.

Query Sequence

>Ga0059261_3667 FitnessBrowser__Korea:Ga0059261_3667
MLEGGIWPVVALSLKVGLVATVVTLPIAFALAWLLARTRFPGKILIDGLVHLPLVVPPVV
TGWLLLLAFAPAGPVGGWLENWFGISVMFRWTGAAIAAGVMALPLMVRAMRLSIEAVDRR
LENAARTLGASRERVFRTITLPLALPGVLAAAVLGFARALGEFGATITFVSNVPGETQTL
PLAIYAALQTPDGEAQVLRLALISVALSLAALVASELLARRAGRGVHVL

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory