Comparing H281DRAFT_00783 FitnessBrowser__Burk376:H281DRAFT_00783 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
5k45A Wolinella succinogenes l-asparaginase p121 + l-glutamic acid (see paper)
49% identity, 91% coverage: 35:361/361 of query aligns to 2:328/328 of 5k45A
5k3oA Wolinella succinogenes l-asparaginase p121 and l-aspartic acid (see paper)
49% identity, 91% coverage: 35:361/361 of query aligns to 2:328/328 of 5k3oA
P06608 L-asparaginase; L-ASNase; L-asparagine amidohydrolase; EC 3.5.1.1 from Dickeya chrysanthemi (Pectobacterium chrysanthemi) (Erwinia chrysanthemi) (see 2 papers)
46% identity, 92% coverage: 30:361/361 of query aligns to 21:348/348 of P06608
2gvnA L-asparaginase from erwinia carotovora in complex with aspartic acid (see paper)
48% identity, 91% coverage: 34:361/361 of query aligns to 2:325/325 of 2gvnA
1hg0A X-ray structure of the complex between erwinia chrysanthemi l- asparaginase and succinic acid (see paper)
46% identity, 91% coverage: 34:361/361 of query aligns to 4:327/327 of 1hg0A
1jsrA Crystal structure of erwinia chrysanthemi l-asparaginase complexed with 6-hydroxy-l-norleucine (see paper)
46% identity, 91% coverage: 34:361/361 of query aligns to 1:324/324 of 1jsrA
1jslA Crystal structure of erwinia chrysanthemi l-asparaginase complexed with 6-hydroxy-d-norleucine (see paper)
46% identity, 91% coverage: 34:361/361 of query aligns to 1:324/324 of 1jslA
P00805 L-asparaginase 2; L-asparaginase II; L-ASNase II; L-asparagine amidohydrolase II; Colaspase; EC 3.5.1.1 from Escherichia coli (strain K12) (see 5 papers)
47% identity, 92% coverage: 29:361/361 of query aligns to 18:348/348 of P00805
Sites not aligning to the query:
2wltA The crystal structure of helicobacter pylori l-asparaginase at 1.4 a resolution (see paper)
46% identity, 91% coverage: 34:361/361 of query aligns to 1:326/326 of 2wltA
7u6mC Albumin binding domain fused to a mutant of the erwinia asparaginase (see paper)
45% identity, 91% coverage: 34:361/361 of query aligns to 19:342/342 of 7u6mC
1ho3A Crystal structure analysis of e. Coli l-asparaginase ii (y25f mutant) (see paper)
47% identity, 91% coverage: 34:361/361 of query aligns to 1:326/326 of 1ho3A
7r5qA Escherichia coli type ii asparaginase n24s mutant in complex with glu (see paper)
45% identity, 91% coverage: 34:361/361 of query aligns to 1:306/306 of 7r5qA
1jazA Crystal structure of monoclinic form of d90e mutant of escherichia coli asparaginase ii (see paper)
45% identity, 91% coverage: 34:361/361 of query aligns to 1:307/307 of 1jazA
6pa3A E. Coli l-asparaginase ii double mutant (t89v,k162t) in complex with l-asn at ph 7.0 (see paper)
46% identity, 91% coverage: 34:361/361 of query aligns to 9:334/334 of 6pa3A
Sites not aligning to the query:
2hlnA L-asparaginase from erwinia carotovora in complex with glutamic acid (see paper)
45% identity, 91% coverage: 34:361/361 of query aligns to 2:308/308 of 2hlnA
1hg1A X-ray structure of the complex between erwinia chrysanthemi l-asparaginase and d-aspartate (see paper)
43% identity, 91% coverage: 34:361/361 of query aligns to 1:306/306 of 1hg1A
1hfwA X-ray structure of the complex between erwinia chrysanthemi l-asparaginase and l-glutamate (see paper)
43% identity, 91% coverage: 34:361/361 of query aligns to 2:307/307 of 1hfwA
6wywA Crystal structure of pseudomonas 7a glutaminase-asparaginase in complex with l-asp at ph 4.5
41% identity, 91% coverage: 34:361/361 of query aligns to 1:317/317 of 6wywA
4pgaA Glutaminase-asparaginase from pseudomonas 7a (see paper)
43% identity, 84% coverage: 59:361/361 of query aligns to 27:330/330 of 4pgaA
Sites not aligning to the query:
1djpA Crystal structure of pseudomonas 7a glutaminase-asparaginase with the inhibitor don covalently bound in the active site (see paper)
43% identity, 84% coverage: 59:361/361 of query aligns to 27:330/330 of 1djpA
Sites not aligning to the query:
>H281DRAFT_00783 FitnessBrowser__Burk376:H281DRAFT_00783
LAASKARDGGASSLTIAAMNAQTSSSSPGAAALLPRIAVLATGGTIAGAAADATNTSGYQ
AGVVGVEQLLAVVPALSTVARIAPEQIASVDSKDMAMPLWTALAQRINALLADDDIDGVV
VTHGTDTLEETAYLLHLTVKSDKPVVLTAAMRPASALSADGPLNLLNAVTVAANAGARGQ
GVLVAFNNKIHSARDVVKTSTYAVDAFQSPEVGALGWVQDGRVEFQRSVVRPHTLSTEFV
IGANWPHVDIVASYAGVSRIAVDALVTAGVRGIVVAGTGNGSIHASLTQALADAASQGVA
VVRSSRVGSGHVMRNGAAADDALGFVSAGSLNPYKARVLLMVALAAGGAGPVALQKAFDT
Y
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Lawrence Berkeley National Laboratory