Comparing H281DRAFT_02154 FitnessBrowser__Burk376:H281DRAFT_02154 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
2xf4A Crystal structure of salmonella enterica serovar typhimurium ycbl (see paper)
54% identity, 98% coverage: 1:210/214 of query aligns to 1:210/210 of 2xf4A
7ev5A Crystal structure of bleg-1 b3 metallo-beta-lactamase (see paper)
34% identity, 95% coverage: 6:209/214 of query aligns to 5:208/209 of 7ev5A
7l0bA Crystal structure of hydroxyacyl glutathione hydrolase (glob) from staphylococcus aureus, apoenzyme (see paper)
28% identity, 91% coverage: 14:208/214 of query aligns to 13:200/202 of 7l0bA
2zwrB Crystal structure of ttha1623 from thermus thermophilus hb8 (see paper)
30% identity, 97% coverage: 1:208/214 of query aligns to 1:200/207 of 2zwrB
2zziA Crystal structure of ttha1623 in a di-iron-bound form (see paper)
31% identity, 95% coverage: 5:208/214 of query aligns to 1:198/198 of 2zziA
6sg9FL uS3m (see paper)
29% identity, 91% coverage: 11:205/214 of query aligns to 62:294/320 of 6sg9FL
Sites not aligning to the query:
5ve5A Crystal structure of persulfide dioxygenase rhodanese fusion protein with rhodanese domain inactivating mutation (c314s) from burkholderia phytofirmans in complex with glutathione (see paper)
29% identity, 95% coverage: 5:208/214 of query aligns to 4:196/350 of 5ve5A
Sites not aligning to the query:
3tp9A Crystal structure of alicyclobacillus acidocaldarius protein with beta-lactamase and rhodanese domains
29% identity, 89% coverage: 15:205/214 of query aligns to 17:223/473 of 3tp9A
3r2uB 2.1 angstrom resolution crystal structure of metallo-beta-lactamase from staphylococcus aureus subsp. Aureus col
26% identity, 91% coverage: 11:205/214 of query aligns to 15:210/336 of 3r2uB
Sites not aligning to the query:
O95571 Persulfide dioxygenase ETHE1, mitochondrial; Ethylmalonic encephalopathy protein 1; Hepatoma subtracted clone one protein; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Homo sapiens (Human) (see 4 papers)
36% identity, 48% coverage: 106:208/214 of query aligns to 109:215/254 of O95571
Sites not aligning to the query:
4chlB Human ethylmalonic encephalopathy protein 1 (hethe1) (see paper)
37% identity, 47% coverage: 106:206/214 of query aligns to 93:197/237 of 4chlB
Sites not aligning to the query:
3r2uA 2.1 angstrom resolution crystal structure of metallo-beta-lactamase from staphylococcus aureus subsp. Aureus col
24% identity, 91% coverage: 11:205/214 of query aligns to 13:222/348 of 3r2uA
2gcuA X-ray structure of gene product from arabidopsis thaliana at1g53580 (see paper)
30% identity, 71% coverage: 55:206/214 of query aligns to 60:201/244 of 2gcuA
4efzA Crystal structure of a hypothetical metallo-beta-lactamase from burkholderia pseudomallei
30% identity, 93% coverage: 15:212/214 of query aligns to 19:242/295 of 4efzA
Q9C8L4 Persulfide dioxygenase ETHE1 homolog, mitochondrial; Glyoxalase II; Glx II; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
30% identity, 71% coverage: 55:206/214 of query aligns to 109:250/294 of Q9C8L4
2q42A Ensemble refinement of the protein crystal structure of glyoxalase ii from arabidopsis thaliana gene at2g31350 (see paper)
27% identity, 91% coverage: 1:195/214 of query aligns to 1:172/254 of 2q42A
Q8ZRM2 Hydroxyacylglutathione hydrolase; Glyoxalase II; Glx II; EC 3.1.2.6 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
30% identity, 91% coverage: 1:195/214 of query aligns to 1:168/251 of Q8ZRM2
2qedA Crystal structure of salmonella thyphimurium lt2 glyoxalase ii (see paper)
30% identity, 91% coverage: 1:195/214 of query aligns to 2:169/252 of 2qedA
Q9SID3 Hydroxyacylglutathione hydrolase 2, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
26% identity, 91% coverage: 1:195/214 of query aligns to 71:242/324 of Q9SID3
4ysbA Crystal structure of ethe1 from myxococcus xanthus (see paper)
28% identity, 88% coverage: 21:209/214 of query aligns to 21:191/225 of 4ysbA
>H281DRAFT_02154 FitnessBrowser__Burk376:H281DRAFT_02154
MKVTLIPVTPFQQNSSLLVCEATGRAAVVDPGGDLDVIQAEIARQNVSVEKVFLTHGHID
HCAGAKTLATHYGVPIEGPHPDERFWLDKLPDQSTRFGFPAADAFEPDRWLDNSDTVQFG
DETLEVYHCPGHTPGHVVFFSRAHRLALVGDVLFAGSIGRTDFPRGNHADLVRSIREKLW
PLGDDVTFVPGHGPTSTFGAERRSNPYVADGVVA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory