Comparing H281DRAFT_02289 FitnessBrowser__Burk376:H281DRAFT_02289 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
5ve5A Crystal structure of persulfide dioxygenase rhodanese fusion protein with rhodanese domain inactivating mutation (c314s) from burkholderia phytofirmans in complex with glutathione (see paper)
79% identity, 100% coverage: 1:356/357 of query aligns to 3:350/350 of 5ve5A
O95571 Persulfide dioxygenase ETHE1, mitochondrial; Ethylmalonic encephalopathy protein 1; Hepatoma subtracted clone one protein; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Homo sapiens (Human) (see 4 papers)
55% identity, 65% coverage: 2:232/357 of query aligns to 23:251/254 of O95571
Sites not aligning to the query:
4chlB Human ethylmalonic encephalopathy protein 1 (hethe1) (see paper)
55% identity, 65% coverage: 2:232/357 of query aligns to 7:235/237 of 4chlB
2gcuA X-ray structure of gene product from arabidopsis thaliana at1g53580 (see paper)
52% identity, 64% coverage: 2:230/357 of query aligns to 3:237/244 of 2gcuA
Q9C8L4 Persulfide dioxygenase ETHE1 homolog, mitochondrial; Glyoxalase II; Glx II; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
52% identity, 64% coverage: 2:230/357 of query aligns to 52:286/294 of Q9C8L4
4ysbA Crystal structure of ethe1 from myxococcus xanthus (see paper)
50% identity, 64% coverage: 2:229/357 of query aligns to 1:224/225 of 4ysbA
4efzA Crystal structure of a hypothetical metallo-beta-lactamase from burkholderia pseudomallei
30% identity, 62% coverage: 7:229/357 of query aligns to 10:275/295 of 4efzA
4yslA Crystal structure of sdoa from pseudomonas putida in complex with glutathione (see paper)
29% identity, 68% coverage: 7:248/357 of query aligns to 12:286/294 of 4yslA
4yskA Crystal structure of apo-form sdoa from pseudomonas putida (see paper)
29% identity, 68% coverage: 7:248/357 of query aligns to 12:286/294 of 4yskA
3r2uB 2.1 angstrom resolution crystal structure of metallo-beta-lactamase from staphylococcus aureus subsp. Aureus col
26% identity, 53% coverage: 2:191/357 of query aligns to 5:210/336 of 3r2uB
Sites not aligning to the query:
2q42A Ensemble refinement of the protein crystal structure of glyoxalase ii from arabidopsis thaliana gene at2g31350 (see paper)
32% identity, 46% coverage: 14:176/357 of query aligns to 12:171/254 of 2q42A
Q9SID3 Hydroxyacylglutathione hydrolase 2, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
32% identity, 45% coverage: 15:176/357 of query aligns to 83:241/324 of Q9SID3
3tp9A Crystal structure of alicyclobacillus acidocaldarius protein with beta-lactamase and rhodanese domains
28% identity, 48% coverage: 2:174/357 of query aligns to 3:198/473 of 3tp9A
3r2uA 2.1 angstrom resolution crystal structure of metallo-beta-lactamase from staphylococcus aureus subsp. Aureus col
26% identity, 48% coverage: 2:174/357 of query aligns to 3:197/348 of 3r2uA
2xf4A Crystal structure of salmonella enterica serovar typhimurium ycbl (see paper)
27% identity, 48% coverage: 24:194/357 of query aligns to 23:208/210 of 2xf4A
7ev5A Crystal structure of bleg-1 b3 metallo-beta-lactamase (see paper)
27% identity, 54% coverage: 3:196/357 of query aligns to 1:209/209 of 7ev5A
Q16775 Hydroxyacylglutathione hydrolase, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Homo sapiens (Human) (see paper)
30% identity, 51% coverage: 12:192/357 of query aligns to 58:236/308 of Q16775
Sites not aligning to the query:
1qh5B Human glyoxalase ii with s-(n-hydroxy-n-bromophenylcarbamoyl) glutathione (see paper)
30% identity, 51% coverage: 12:192/357 of query aligns to 10:188/260 of 1qh5B
Sites not aligning to the query:
1qh5A Human glyoxalase ii with s-(n-hydroxy-n-bromophenylcarbamoyl) glutathione (see paper)
30% identity, 51% coverage: 12:192/357 of query aligns to 10:188/260 of 1qh5A
Sites not aligning to the query:
1qh3A Human glyoxalase ii with cacodylate and acetate ions present in the active site (see paper)
30% identity, 51% coverage: 12:192/357 of query aligns to 10:188/260 of 1qh3A
Sites not aligning to the query:
>H281DRAFT_02289 FitnessBrowser__Burk376:H281DRAFT_02289
VLIFRQLFDQQSSTYTYLLADSATREAILIDPVFEQVRRDTALIEELGLHLLYTIDTHVH
ADHVTGAWLLKRHTGSQIAISAASGAQGADRYLNHGEQCVFGSRHLEVRATPGHTNGCIS
LALDDGSMMFTGDCLLIRGTGRTDFQHGDAHAMFRSVQNQIFIQPDTCLLYPAHDYRGLT
VTSVGEERRFNPRLGGELCEDDFVGYVTNLRLPHPKQIDIAVPANLKCGVATSDPTQTAE
PEWAPLAYTFAGIWEISPQWLEDNLRSVQIVDVREPDEFNGPLGRIPAAQLISLGDLAAR
ASELKKERPIVAVCRAGGRSAQATVILRQAGFNDVANLAGGMLRWRAEGRVVENAAM
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory