Comparing H281DRAFT_02293 FitnessBrowser__Burk376:H281DRAFT_02293 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
1u08A Crystal structure and reactivity of ybdl from escherichia coli identify a methionine aminotransferase function. (see paper)
49% identity, 98% coverage: 8:384/384 of query aligns to 5:382/382 of 1u08A
2o0rA The three-dimensional structure of n-succinyldiaminopimelate aminotransferase from mycobacterium tuberculosis (see paper)
37% identity, 97% coverage: 9:381/384 of query aligns to 4:380/385 of 2o0rA
1v2fA Crystal structure of t.Th hb8 glutamine aminotransferase complex with 3-phenylpropionate (see paper)
36% identity, 96% coverage: 17:384/384 of query aligns to 13:367/368 of 1v2fA
1v2eA Crystal structure of t.Th hb8 glutamine aminotransferase complex with a-keto-g-methylthiobutyrate (see paper)
36% identity, 96% coverage: 17:384/384 of query aligns to 13:367/368 of 1v2eA
1gdeA Crystal structure of pyrococcus protein a-1 e-form (see paper)
32% identity, 93% coverage: 26:381/384 of query aligns to 22:378/388 of 1gdeA
1gd9A Crystall structure of pyrococcus protein-a1 (see paper)
32% identity, 93% coverage: 26:381/384 of query aligns to 22:378/388 of 1gd9A
4wljA High resolution crystal structure of human kynurenine aminotransferase-i in complex with aminooxyacetate (see paper)
32% identity, 91% coverage: 24:374/384 of query aligns to 20:399/413 of 4wljA
Sites not aligning to the query:
1w7nA Crystal structure of human kynurenine aminotransferase i in pmp form (see paper)
32% identity, 91% coverage: 24:374/384 of query aligns to 20:402/415 of 1w7nA
1w7mA Crystal structure of human kynurenine aminotransferase i in complex with l-phe (see paper)
32% identity, 91% coverage: 24:374/384 of query aligns to 20:402/415 of 1w7mA
Sites not aligning to the query:
1w7lA Crystal structure of human kynurenine aminotransferase i (see paper)
32% identity, 91% coverage: 24:374/384 of query aligns to 20:402/415 of 1w7lA
Q16773 Kynurenine--oxoglutarate transaminase 1; Cysteine-S-conjugate beta-lyase; Glutamine transaminase K; GTK; Glutamine--phenylpyruvate transaminase; Kynurenine aminotransferase 1; Kynurenine aminotransferase I; KATI; Kynurenine--oxoglutarate transaminase I; EC 2.6.1.7; EC 4.4.1.13; EC 2.6.1.64 from Homo sapiens (Human) (see paper)
31% identity, 97% coverage: 1:374/384 of query aligns to 1:408/422 of Q16773
3fvuA Crystal structure of human kynurenine aminotransferase i in complex with indole-3-acetic acid (see paper)
32% identity, 91% coverage: 24:374/384 of query aligns to 20:405/419 of 3fvuA
Sites not aligning to the query:
3fvsB Human kynurenine aminotransferase i in complex with glycerol (see paper)
32% identity, 91% coverage: 24:374/384 of query aligns to 20:405/419 of 3fvsB
Sites not aligning to the query:
5verA Mouse kynurenine aminotransferase iii, re-refinement of the PDB structure 3e2z (see paper)
31% identity, 93% coverage: 16:374/384 of query aligns to 10:399/410 of 5verA
Sites not aligning to the query:
5vepA Mouse kynurenine aminotransferase iii, re-refinement of the PDB structure 3e2f (see paper)
31% identity, 93% coverage: 16:374/384 of query aligns to 10:399/410 of 5vepA
Sites not aligning to the query:
3e2zA Crystal structure of mouse kynurenine aminotransferase iii in complex with kynurenine (see paper)
31% identity, 93% coverage: 16:374/384 of query aligns to 10:399/410 of 3e2zA
3e2yA Crystal structure of mouse kynurenine aminotransferase iii in complex with glutamine (see paper)
31% identity, 93% coverage: 16:374/384 of query aligns to 10:399/410 of 3e2yA
1j32A Aspartate aminotransferase from phormidium lapideum
32% identity, 92% coverage: 30:381/384 of query aligns to 31:380/388 of 1j32A
2r5eA Aedes kynurenine aminotransferase in complex with glutamine (see paper)
33% identity, 93% coverage: 24:381/384 of query aligns to 22:412/419 of 2r5eA
Sites not aligning to the query:
2r5cB Aedes kynurenine aminotransferase in complex with cysteine (see paper)
33% identity, 93% coverage: 24:381/384 of query aligns to 22:412/419 of 2r5cB
Sites not aligning to the query:
>H281DRAFT_02293 FitnessBrowser__Burk376:H281DRAFT_02293
MQSATQARSKLPDVGTTIFTVIGQLAAQHDALNLSQGAPNFAPDAKLVDGVAQAMRDGHN
QYAPMAGIAALREALADKVQTLYGVRYDPTSEVTVIASASEGLYSTISALVHPGDEVIYF
EPSFDSYGPIVRLQGATPVPIKLSLSDFRVNWDEVAAAITPKTRMIIINTPHNPTATVFS
EADVARLKAITRNTDIVILADEVYEHVVFDGAKHQSMACHSELAERSVIVSSFGKSYHVT
GWRVGYCLAPAELMNEIRKVHQFMVFSADTPMQYAFVDALSNRESYLGLSAFYQQKRDLL
AHALSESRFELLPSEGSFFMLARFRGFSDESDSDFVLRLIRDARVATIPLSAFYSDGTDS
GLIRLSFSKDDATLIEGARRLCEI
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory