Comparing H281DRAFT_02776 FitnessBrowser__Burk376:H281DRAFT_02776 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
5x7uA Trehalose synthase from thermobaculum terrenum (see paper)
44% identity, 88% coverage: 6:491/554 of query aligns to 4:489/546 of 5x7uA
Sites not aligning to the query:
5gtwA The n253r mutant structures of trehalose synthase from deinococcus radiodurans display two different active-site conformations
43% identity, 97% coverage: 6:542/554 of query aligns to 3:546/548 of 5gtwA
5ykbD The n253f mutant structure of trehalose synthase from deinococcus radiodurans reveals an open active-site conformation (see paper)
42% identity, 97% coverage: 6:542/554 of query aligns to 3:522/523 of 5ykbD
3zoaA The structure of trehalose synthase (tres) of mycobacterium smegmatis in complex with acarbose (see paper)
42% identity, 88% coverage: 6:491/554 of query aligns to 6:495/548 of 3zoaA
Sites not aligning to the query:
3zo9A The structure of trehalose synthase (tres) of mycobacterium smegmatis (see paper)
42% identity, 88% coverage: 6:491/554 of query aligns to 7:496/549 of 3zo9A
A0R6E0 Trehalose synthase/amylase TreS; Maltose alpha-D-glucosyltransferase; MTase; EC 3.2.1.1; EC 5.4.99.16 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see 2 papers)
42% identity, 88% coverage: 6:491/554 of query aligns to 35:533/593 of A0R6E0
5jy7B Complex of mycobacterium smegmatis trehalose synthase with maltokinase (see paper)
42% identity, 88% coverage: 6:491/554 of query aligns to 19:517/571 of 5jy7B
3zoaB The structure of trehalose synthase (tres) of mycobacterium smegmatis in complex with acarbose (see paper)
42% identity, 88% coverage: 6:491/554 of query aligns to 19:517/571 of 3zoaB
Sites not aligning to the query:
4lxfA Crystal structure of m. Tuberculosis tres (see paper)
42% identity, 88% coverage: 6:491/554 of query aligns to 32:519/570 of 4lxfA
4lxfB Crystal structure of m. Tuberculosis tres (see paper)
40% identity, 88% coverage: 6:490/554 of query aligns to 32:494/546 of 4lxfB
4aieA Structure of glucan-1,6-alpha-glucosidase from lactobacillus acidophilus ncfm (see paper)
32% identity, 88% coverage: 6:493/554 of query aligns to 3:498/537 of 4aieA
2ze0A Alpha-glucosidase gsj (see paper)
33% identity, 85% coverage: 6:474/554 of query aligns to 4:466/531 of 2ze0A
8ibkA Crystal structure of bacillus sp. Ahu2216 gh13_31 alpha-glucosidase e256q/n258g in complex with maltotriose (see paper)
29% identity, 97% coverage: 6:540/554 of query aligns to 3:543/546 of 8ibkA
5wczA Crystal structure of wild-type mall from bacillus subtilis with ts analogue 1-deoxynojirimycin (see paper)
29% identity, 88% coverage: 6:495/554 of query aligns to 2:513/556 of 5wczA
4m56A The structure of wild-type mall from bacillus subtilis (see paper)
29% identity, 88% coverage: 6:495/554 of query aligns to 2:513/555 of 4m56A
4mazA The structure of mall mutant enzyme v200s from bacillus subtilus (see paper)
29% identity, 88% coverage: 6:495/554 of query aligns to 2:516/559 of 4mazA
O06994 Oligo-1,6-glucosidase 1; Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase 1; Sucrase-isomaltase 1; Isomaltase 1; EC 3.2.1.10 from Bacillus subtilis (strain 168) (see paper)
29% identity, 88% coverage: 6:495/554 of query aligns to 4:518/561 of O06994
7lv6B The structure of mall mutant enzyme s536r from bacillus subtilis
29% identity, 88% coverage: 6:495/554 of query aligns to 2:516/559 of 7lv6B
4h8vA Crystal structure of the trehalulose synthase mutb in complex with trehalulose
31% identity, 90% coverage: 6:504/554 of query aligns to 6:523/557 of 4h8vA
2pwdA Crystal structure of the trehalulose synthase mutb from pseudomonas mesoacidophila mx-45 complexed to the inhibitor deoxynojirmycin (see paper)
31% identity, 90% coverage: 6:504/554 of query aligns to 6:523/557 of 2pwdA
>H281DRAFT_02776 FitnessBrowser__Burk376:H281DRAFT_02776
MLNDLWYKNAIVYCLSVGTFMDANGDGVGDFQGLLRRLDYLQGLGVTTIWLMPFQPSPGR
DNGYDISDYYNVDPKYGTLGDFSEFTHACRERGLRVMIDLVVNHTSDQHPWFREARSDPD
SQYRDWYVWSDKQPPNAKDGVVFPGVQKSTWTFDKQAKRWYFHRFYEFQPDLNTANPYVR
AELLKIMGFWIQLGVSGFRMDAVPFVIATKGPKVREPVEQYDMLREFREFLQWRQGDAII
LAEANVLPDTDLEYFGDEGERLQMMFNFQLNQNTFYALATGDTAPLKKALTATRPRPATA
QWGVFLRNHDELDLGRLTPEQREAVFAAFAPEPDMQLYERGIRRRLAPMLAGDRRRLELA
YSLMLTLPGTPVFRYGDEIGMGDDLRLPERECARTPMQWSTEPEGGFTKHAKPPCRVITG
GAYGFERVNVASQRRDPNSFLNWMERMIRMRREVPEISWGDFDVLRTSRSDVLALRFDWR
NNSVLCLHNFGAEACTVKFRSGCNEPGQNRLINLLSDEHSEEQDDGRHAVVLEPYGYRWY
RVGGLDYLLRRSEI
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory