Comparing H281DRAFT_02953 FitnessBrowser__Burk376:H281DRAFT_02953 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 4 hits to proteins with known functional sites (download)
3dbnA Crystal structure of the streptoccocus suis serotype2 d- mannonate dehydratase in complex with its substrate (see paper)
52% identity, 97% coverage: 1:341/353 of query aligns to 3:331/349 of 3dbnA
3bdkA Crystal structure of streptococcus suis mannonate dehydratase complexed with substrate analogue
52% identity, 97% coverage: 1:341/353 of query aligns to 3:331/349 of 3bdkA
4eayA Crystal structures of mannonate dehydratase from escherichia coli strain k12 complexed with d-mannonate (see paper)
40% identity, 96% coverage: 1:338/353 of query aligns to 3:385/395 of 4eayA
4eacC Crystal structure of mannonate dehydratase from escherichia coli strain k12 (see paper)
40% identity, 96% coverage: 1:338/353 of query aligns to 3:385/396 of 4eacC
>H281DRAFT_02953 FitnessBrowser__Burk376:H281DRAFT_02953
LKMTFRWYGDADPVPLAYIRQIPGMVGVVSAVYDVPVGDVWPVDTIRSLKEKIEAHGLTL
DVIESVPVHEDIKLGKPTRDTLIANYGQTLRNLGACGVKVVCYNFMPVFDWTRTSLEMPL
PDGSTTLAFDTQAIRELDVSQGIQLPGWDASYRPEQLKALLREYEALDEAGLWANLDYFL
RAIIPVAKEAGIKMAIHPDDPPRPIFGLPRIVKNRADLQRVLAIVDDPANGLTLCSGSLG
ADLQNDIPALVREFGARGRIHFAHLRNVQTNAAGDFHETSHRSADGSLDMAEIVKAYFET
GFEGYARPDHGRMIWGETGRAGYGLFDRALGAVYLNGIWEGLAKQHPTDHAAE
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory