Comparing H281DRAFT_03229 FitnessBrowser__Burk376:H281DRAFT_03229 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 16 hits to proteins with known functional sites (download)
1kwkA Crystal structure of thermus thermophilus a4 beta-galactosidase in complex with galactose (see paper)
53% identity, 99% coverage: 3:658/661 of query aligns to 2:642/644 of 1kwkA
1kwgA Crystal structure of thermus thermophilus a4 beta-galactosidase (see paper)
53% identity, 99% coverage: 3:658/661 of query aligns to 2:642/644 of 1kwgA
O69315 Beta-galactosidase; Beta-gal; Lactase; EC 3.2.1.23 from Thermus thermophilus (see paper)
53% identity, 99% coverage: 3:658/661 of query aligns to 2:642/645 of O69315
6lvwA Polyextremophilic beta-galactosidase from the antarctic haloarchaeon halorubrum lacusprofundi (see paper)
43% identity, 99% coverage: 1:657/661 of query aligns to 1:658/668 of 6lvwA
3ttyA Crystal structure of beta-galactosidase from bacillus circulans sp. Alkalophilus in complex with galactose (see paper)
29% identity, 98% coverage: 7:653/661 of query aligns to 15:661/675 of 3ttyA
3ttsA Crystal structure of beta-galactosidase from bacillus circulans sp. Alkalophilus (see paper)
29% identity, 98% coverage: 7:653/661 of query aligns to 15:661/675 of 3ttsA
5e9aB Crystal structure analysis of the cold-adamped beta-galactosidase from rahnella sp. R3 (see paper)
30% identity, 90% coverage: 4:601/661 of query aligns to 16:610/684 of 5e9aB
4uzsA Crystal structure of bifidobacterium bifidum beta-galactosidase (see paper)
29% identity, 99% coverage: 4:659/661 of query aligns to 21:686/687 of 4uzsA
4ucfA Crystal structure of bifidobacterium bifidum beta-galactosidase in complex with alpha-galactose (see paper)
29% identity, 99% coverage: 4:659/661 of query aligns to 20:681/682 of 4ucfA
Sites not aligning to the query:
4uniA Beta-(1,6)-galactosidase from bifidobacterium animalis subsp. Lactis bl-04 in complex with galactose (see paper)
28% identity, 99% coverage: 3:659/661 of query aligns to 19:688/689 of 4uniA
8ibtA Crystal structure of gh42 beta-galactosidase bibga42a from bifidobacterium longum subspecies infantis e318s mutant in complex with lacto-n-tetraose (see paper)
29% identity, 99% coverage: 4:659/661 of query aligns to 22:688/694 of 8ibtA
4uozA Beta-(1,6)-galactosidase from bifidobacterium animalis subsp. Lactis bl-04 nucleophile mutant e324a in complex with galactose (see paper)
28% identity, 99% coverage: 3:659/661 of query aligns to 18:687/688 of 4uozA
8ibsA Crystal structure of gh42 beta-galactosidase bibga42a from bifidobacterium longum subspecies infantis e160a/e318a mutant in complex with galactose (see paper)
30% identity, 94% coverage: 4:626/661 of query aligns to 22:647/691 of 8ibsA
5dfaA 3d structure of the e323a catalytic mutant of gan42b, a gh42 beta- galactosidase from g. Stearothermophilus (see paper)
30% identity, 74% coverage: 4:492/661 of query aligns to 17:503/685 of 5dfaA
O31529 Beta-galactosidase YesZ; Beta-gal; Probable rhamnogalacturonan beta-galactosidase; EC 3.2.1.23 from Bacillus subtilis (strain 168) (see paper)
28% identity, 79% coverage: 4:528/661 of query aligns to 7:513/663 of O31529
O58247 Exo-beta-D-glucosaminidase; GlcNase; EC 3.2.1.- from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see paper)
24% identity, 48% coverage: 13:329/661 of query aligns to 33:365/778 of O58247
>H281DRAFT_03229 FitnessBrowser__Burk376:H281DRAFT_03229
MRLGVCYYPEHWPESMWEDDARRMKALGIEQVRIAEFAWSRIEPTPGEYDWAWLDRAIEV
LGAAGLQVVMCTPTATPPKWLIDRHPDILPIGADGRPRAFGSRRHYDFSSPSYFSASQKI
CTAIAERYGKHPAVAYWQTDNEFGCHHTVVSYSPAAVARFREWLKARYTTIDELNRAWGT
VFWSMEYRSFDEIDAPVATVTEAHPSHRLDYRRFASDEVARYNRMQVEIIRAHSPGRPVA
HNFMQLFTEFDHYKVAADLDVAAWDSYPLGALEEQWFAPDVKARWLRSGHPDFASFNHDV
YRGMSKLPFWVMEQQPGPVNWAQWNPAPLPGMVRLWSWEAFAHGAGCVSYFRWRQAPFAQ
EQMHAGLNTPDNRLDVGGSEAAQVASEIRTVLAANAHADAAVRSKVALVYDYEAKWLFEI
HPQGADFHYPRFAFEYYSALRALGLDVDVVPVDASLDGYSLIVVPPLPVVPADLAARLAS
SGAQVVLGPRTGSKTQDLQIPANLPPGALADVLPLRVWRVESMRPNVTEAVRLAGTQDAS
VEDGVARHWRDFIESKDTNSFDVLARFADGQPAYVRSGAFHYLASLFDDALTTRLFEQIA
QRAGVETVRLGESVRISRCGALTYVFNYGDNAHTITGAADNAFVIGSSTVEPQGVAVYRA
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Lawrence Berkeley National Laboratory