Comparing H281DRAFT_03923 FitnessBrowser__Burk376:H281DRAFT_03923 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 8 hits to proteins with known functional sites (download)
4wjiA Crystal structure of cyclohexadienyl dehydrogenase from sinorhizobium meliloti in complex with NADP and tyrosine
40% identity, 93% coverage: 6:295/313 of query aligns to 1:283/293 of 4wjiA
3gggD The crystal structure of a. Aeolicus prephenate dehydrogenase in complex with tyrosine and NAD+ (see paper)
35% identity, 94% coverage: 4:297/313 of query aligns to 8:292/293 of 3gggD
3ggpA Crystal structure of prephenate dehydrogenase from a. Aeolicus in complex with hydroxyphenyl propionate and NAD+ (see paper)
35% identity, 94% coverage: 5:297/313 of query aligns to 1:284/286 of 3ggpA
3ggoA Crystal structure of prephenate dehydrogenase from a. Aeolicus with hpp and nadh (see paper)
35% identity, 94% coverage: 5:297/313 of query aligns to 1:284/285 of 3ggoA
5uyyA Crystal structure of prephenate dehydrogenase tyra from bacillus anthracis in complex with l-tyrosine (see paper)
35% identity, 91% coverage: 10:295/313 of query aligns to 10:287/373 of 5uyyA
Sites not aligning to the query:
6u60B Crystal structure of prephenate dehydrogenase tyra from bacillus anthracis in complex with NAD and l-tyrosine (see paper)
35% identity, 91% coverage: 10:295/313 of query aligns to 2:279/365 of 6u60B
Sites not aligning to the query:
3b1fA Crystal structure of prephenate dehydrogenase from streptococcus mutans (see paper)
34% identity, 94% coverage: 5:299/313 of query aligns to 2:286/286 of 3b1fA
2f1kA Crystal structure of synechocystis arogenate dehydrogenase (see paper)
30% identity, 93% coverage: 11:300/313 of query aligns to 2:279/279 of 2f1kA
>H281DRAFT_03923 FitnessBrowser__Burk376:H281DRAFT_03923
VTDVAAFSFNKLVIFGVGLIGGSLARALRERGEADGARTVIGVGRSAASTGRAVELGVID
SSAALSDDAALREALADADVVLLAAPVAQTQPLLECIAPFLGADTIVTDAGSTKSDVVAA
ARAALGARIGQFVPGHPIAGRESSGVEAALPDLYVGRNVVLCPLPENAPGTVERIAAMWR
ATGALVRDMAPEQHDRVFASVSHLPHVLSFALVEQILNSPDAALKFSFAAGGFRDFTRIA
ASSPEMWRDVCIANRVALLDELDAYSAVLARLRTAIEAADGAALEAVFARSRLARTEWQE
QRAGGGAPGDASK
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory