Comparing H281DRAFT_06059 FitnessBrowser__Burk376:H281DRAFT_06059 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P9WGB5 O-succinylhomoserine sulfhydrylase; OSH sulfhydrylase; OSHS sulfhydrylase; EC 2.5.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
48% identity, 100% coverage: 1:395/396 of query aligns to 13:406/406 of P9WGB5
4omaA The crystal structure of methionine gamma-lyase from citrobacter freundii in complex with l-cycloserine pyridoxal-5'-phosphate (see paper)
48% identity, 93% coverage: 25:394/396 of query aligns to 27:392/396 of 4omaA
3jwbA Crystal structure of l-methionine gamma-lyase from citrobacter freundii with norleucine (see paper)
48% identity, 93% coverage: 25:394/396 of query aligns to 27:392/396 of 3jwbA
3jwaA Crystal structure of l-methionine gamma-lyase from citrobacter freundii with methionine phosphinate (see paper)
48% identity, 93% coverage: 25:394/396 of query aligns to 27:392/396 of 3jwaA
3jw9A Crystal structure of l-methionine gamma-lyase from citrobacter freundii with s-ethyl-cysteine (see paper)
48% identity, 93% coverage: 25:394/396 of query aligns to 27:392/396 of 3jw9A
5m3zA Crystal structure of citrobacter freundii methionine gamma-lyase with c115h replacement in the complex with l-norleucine (see paper)
48% identity, 93% coverage: 25:394/396 of query aligns to 26:391/395 of 5m3zA
4hf8A Crystal structure of l-methionine gamma-lyase from citrobacter freundii with glycine (see paper)
48% identity, 93% coverage: 25:394/396 of query aligns to 27:392/396 of 4hf8A
6egrA Crystal structure of citrobacter freundii methionine gamma-lyase with v358y replacement (see paper)
48% identity, 93% coverage: 25:394/396 of query aligns to 27:392/396 of 6egrA
5dx5A Crystal structure of methionine gamma-lyase from clostridium sporogenes (see paper)
44% identity, 98% coverage: 5:394/396 of query aligns to 6:394/399 of 5dx5A
3mkjA Methionine gamma-lyase from citrobacter freundii with pyridoximine-5'- phosphate (see paper)
47% identity, 93% coverage: 25:394/396 of query aligns to 27:381/386 of 3mkjA
1e5fA Methionine gamma-lyase (mgl) from trichomonas vaginalis
37% identity, 97% coverage: 9:394/396 of query aligns to 7:389/393 of 1e5fA
1e5eA Methionine gamma-lyase (mgl) from trichomonas vaginalis in complex with propargylglycine
37% identity, 97% coverage: 9:394/396 of query aligns to 7:389/394 of 1e5eA
5x30C Crystal structure of pseudomonas putida methionine gamma-lyase c116h mutant with l-homocysteine intermediates. (see paper)
38% identity, 98% coverage: 6:394/396 of query aligns to 4:389/393 of 5x30C
1pg8A Crystal structure of l-methionine alpha-, gamma-lyase
38% identity, 98% coverage: 6:394/396 of query aligns to 9:394/398 of 1pg8A
P13254 L-methionine gamma-lyase; MGL; Homocysteine desulfhydrase; L-methioninase; EC 4.4.1.11; EC 4.4.1.2 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 3 papers)
38% identity, 98% coverage: 6:394/396 of query aligns to 9:394/398 of P13254
3vk3A Crystal structure of l-methionine gamma-lyase from pseudomonas putida c116h mutant complexed with l-methionine (see paper)
38% identity, 98% coverage: 6:394/396 of query aligns to 8:393/397 of 3vk3A
5x2xA Crystal structure of pseudomonas putida methionine gamma-lyase wild type with l-homocysteine intermediates (see paper)
38% identity, 98% coverage: 6:394/396 of query aligns to 3:388/392 of 5x2xA
5x2wA Crystal structure of pseudomonas putida methionine gamma-lyase wild type with l-methionine intermediates (see paper)
38% identity, 98% coverage: 6:394/396 of query aligns to 3:388/392 of 5x2wA
7ba4A Structure of cystathionine gamma-lyase from pseudomonas aeruginosa
43% identity, 86% coverage: 54:395/396 of query aligns to 34:372/377 of 7ba4A
4iyoD Crystal structure of cystathionine gamma lyase from xanthomonas oryzae pv. Oryzae (xometc) in complex with e-site serine, a-site serine, a- site external aldimine structure with aminoacrylate and a-site iminopropionate intermediates (see paper)
43% identity, 86% coverage: 53:394/396 of query aligns to 43:380/384 of 4iyoD
>H281DRAFT_06059 FitnessBrowser__Burk376:H281DRAFT_06059
MDDSLNFDTLAVRSGTVRSDFNEHSEAIFLTSSFVFASAADAAERFKNSEDYYTYSRFTN
PTVSMFQDRLAALEGGEACMATASGMAAIMSVVMSTLQAGDHLVSSQALFGSTLGMFSQI
FSKFGITTTFVDPTNLDAWKNAVRPETKMFFLETPSNPLTEVADIEAISKIAKAANALFV
VDNCFCSPALQQPLKLGADVVMHSATKFLDGQGRVLGGALVGSKKFIMEKVFPFVRSAGP
TLSAFNAWVLLKGMETLSLRVEKQSANALEIARWLDDHPSVKRVFYPGLESHPQHALAMR
QQKAGGAIVSFELKGDTPEQMRANAWRVIDSTKICSITGNLGDTRTTITHPATTTHGRVT
PEARAAAGITEGLIRLAVGLENAADIRADLERGLAG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory