Comparing H281DRAFT_06264 FitnessBrowser__Burk376:H281DRAFT_06264 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 12 hits to proteins with known functional sites (download)
P0A7B5 Glutamate 5-kinase; Gamma-glutamyl kinase; GK; EC 2.7.2.11 from Escherichia coli (strain K12) (see paper)
44% identity, 98% coverage: 5:370/372 of query aligns to 1:365/367 of P0A7B5
2j5tD Glutamate 5-kinase from escherichia coli complexed with glutamate (see paper)
44% identity, 98% coverage: 7:370/372 of query aligns to 1:363/365 of 2j5tD
2j5vB Glutamate 5-kinase from escherichia coli complexed with glutamyl-5- phosphate and pyroglutamic acid (see paper)
40% identity, 98% coverage: 7:370/372 of query aligns to 1:323/325 of 2j5vB
2j5vA Glutamate 5-kinase from escherichia coli complexed with glutamyl-5- phosphate and pyroglutamic acid (see paper)
39% identity, 98% coverage: 7:370/372 of query aligns to 1:321/323 of 2j5vA
7wx3B Gk domain of drosophila p5cs filament with glutamate, atp, and NADPH (see paper)
35% identity, 69% coverage: 2:257/372 of query aligns to 6:254/258 of 7wx3B
7f5xA Gk domain of drosophila p5cs filament with glutamate (see paper)
34% identity, 69% coverage: 2:257/372 of query aligns to 6:232/236 of 7f5xA
2akoA Crystal structure of glutamate 5-kinase from campylobacter jejuni
34% identity, 64% coverage: 9:245/372 of query aligns to 1:224/241 of 2akoA
Q8U122 Uridylate kinase; UK; Uridine monophosphate kinase; UMP kinase; UMPK; EC 2.7.4.22 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (see paper)
31% identity, 29% coverage: 153:259/372 of query aligns to 120:223/225 of Q8U122
Sites not aligning to the query:
2bmuB Ump kinase from pyrococcus furiosus complexed with its substrate ump and its substrate analog amppnp (see paper)
31% identity, 29% coverage: 153:259/372 of query aligns to 121:224/226 of 2bmuB
Sites not aligning to the query:
2ji5A Structure of ump kinase from pyrococcus furiosus complexed with utp
30% identity, 29% coverage: 153:259/372 of query aligns to 122:217/219 of 2ji5A
Sites not aligning to the query:
3ll5A Crystal structure of t. Acidophilum isopentenyl phosphate kinase product complex (see paper)
30% identity, 20% coverage: 123:197/372 of query aligns to 113:188/233 of 3ll5A
Sites not aligning to the query:
3lkkB Crystal structure of the isopentenyl phosphate kinase substrate complex (see paper)
30% identity, 20% coverage: 123:197/372 of query aligns to 114:189/238 of 3lkkB
Sites not aligning to the query:
>H281DRAFT_06264 FitnessBrowser__Burk376:H281DRAFT_06264
MRSVIADSRRLVVKVGSSLVTNDGRGLDHAAIGRWAAQIAALRAQSKEVVLVSSGAIAEG
MQRLGWSKRPREIDELQAAAAVGQMGLAQVYESRFAEHSIQTAQILLTHADLADRERYLN
ARSTLLTLLRLGVVPIINENDTVVTDEIKFGDNDTLGALVANLIEGDALIILTDQQGLFT
ADPRKDPNATLVQQADAGAPDLEAMAGGAGSSLGRGGMLTKILAAKRAAHSGANTVIASG
READVLSRLASGEAIGTQLIARTARMAARKQWMADHLQVRGHVVIDDGAVEKLTAGGKSL
LPIGIVGVQGAFARGEVIACLNAAGREVARGLTNYSSAETKLIQRRPSGEIESVLGYMLE
PELIHRDNLVLV
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory