Comparing HSERO_RS05475 FitnessBrowser__HerbieS:HSERO_RS05475 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3ll3A The crystal structure of ligand bound xylulose kinase from lactobacillus acidophilus
40% identity, 96% coverage: 8:505/520 of query aligns to 3:488/492 of 3ll3A
3ll3B The crystal structure of ligand bound xylulose kinase from lactobacillus acidophilus
40% identity, 96% coverage: 8:505/520 of query aligns to 2:486/490 of 3ll3B
6k76A Glycerol kinase form thermococcus kodakarensis, complex structure with substrate.
28% identity, 86% coverage: 10:458/520 of query aligns to 1:435/485 of 6k76A
P18157 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Bacillus subtilis (strain 168) (see paper)
27% identity, 92% coverage: 6:482/520 of query aligns to 1:474/496 of P18157
P09099 Xylulose kinase; XK; Xylulokinase; 1-deoxy-D-xylulokinase; EC 2.7.1.17; EC 2.7.1.- from Escherichia coli (strain K12) (see paper)
27% identity, 92% coverage: 11:487/520 of query aligns to 3:465/484 of P09099
5ya2A Crystal structure of lsrk-hpr complex with adp (see paper)
27% identity, 92% coverage: 9:487/520 of query aligns to 4:472/478 of 5ya2A
5ya1A Crystal structure of lsrk-hpr complex with atp (see paper)
27% identity, 92% coverage: 9:487/520 of query aligns to 4:472/478 of 5ya1A
2itmA Crystal structure of the e. Coli xylulose kinase complexed with xylulose (see paper)
26% identity, 92% coverage: 11:487/520 of query aligns to 3:457/476 of 2itmA
3ge1A 2.7 angstrom crystal structure of glycerol kinase (glpk) from staphylococcus aureus in complex with adp and glycerol
26% identity, 89% coverage: 5:468/520 of query aligns to 1:461/499 of 3ge1A
3h3nX Glycerol kinase h232r with glycerol (see paper)
25% identity, 92% coverage: 5:480/520 of query aligns to 1:473/501 of 3h3nX
O34153 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Enterococcus casseliflavus (Enterococcus flavescens) (see 3 papers)
25% identity, 92% coverage: 5:480/520 of query aligns to 2:474/506 of O34153
6udeB Crystal structure of glycerol kinase from elizabethkingia anophelis nuhp1 in complex with adp and glycerol
24% identity, 92% coverage: 8:486/520 of query aligns to 3:475/495 of 6udeB
O34154 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Enterococcus faecalis (strain ATCC 700802 / V583) (see 2 papers)
25% identity, 94% coverage: 8:496/520 of query aligns to 5:492/501 of O34154
Sites not aligning to the query:
Q5HGD2 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Staphylococcus aureus (strain COL)
26% identity, 89% coverage: 6:468/520 of query aligns to 1:460/498 of Q5HGD2
O86033 Glycerol kinase; ATP:glycerol 3-phosphotransferase; Glycerokinase; GK; EC 2.7.1.30 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
26% identity, 88% coverage: 9:463/520 of query aligns to 4:456/497 of O86033
1gllO Escherichia coli glycerol kinase mutant with bound atp analog showing substantial domain motion (see paper)
25% identity, 88% coverage: 8:465/520 of query aligns to 3:453/494 of 1gllO
1gljO Escherichia coli glycerol kinase mutant with bound atp analog showing substantial domain motion (see paper)
25% identity, 88% coverage: 8:465/520 of query aligns to 3:453/494 of 1gljO
1bwfO Escherichia coli glycerol kinase mutant with bound atp analog showing substantial domain motion (see paper)
25% identity, 88% coverage: 8:465/520 of query aligns to 3:453/494 of 1bwfO
3kzbA Crystal structure of xylulokinase from chromobacterium violaceum
27% identity, 84% coverage: 5:439/520 of query aligns to 1:431/498 of 3kzbA
1bu6Y Crystal structures of escherichia coli glycerol kinase and the mutant a65t in an inactive tetramer: conformational changes and implications for allosteric regulation (see paper)
25% identity, 88% coverage: 8:465/520 of query aligns to 3:457/499 of 1bu6Y
>HSERO_RS05475 FitnessBrowser__HerbieS:HSERO_RS05475
MSTSALARYMLGVDIGTTSTKSVVFTLDGKVVAQHAEEYPVLCTEPGMAEQDPEQIVAAA
LASIAGAVKAAKAAPQEIALLSFSAAMHSVIALDAENRLLSNSITWGDIRASVWAERIKH
EHDGNAIYRRTGTPVHPMSPLCKLMWMRHEKPDVFHRAARFVGIKEYLLYQLFGQWVVDH
SIASATGMFNLRELAWDQGALALLGVRPDQLPTPVPTTHRLPALSSEMAQRLGLSVDTPF
IIGANDGVLSNLGVNAIEIGHVAVTIGTSGAMRTVIDEPRTDPQGRLFCYALTEKHWVVG
GPVNNGGNIFRWVRDELATAEAAAAREEGVDPYEALTRIAEKVRPGAEGLLFHPFMAGER
APLWNADLRGSFFGLALHHGKHHMIRAALEGVIFNLYSILPALEELVGPTKRMMATGGFA
RSALWRQMMADIFNREVVVPESVESSCLGAAVLGAWALGLVPSLSVISGMVGSTNHHAPE
AEAVAVYGRLQPIFAAIPAKLEAEYHAIAAFQREAGRPHP
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory