SitesBLAST

A0A1J1DL12 2-iminobutanoate/2-iminopropanoate deaminase; Allergen Der f 34; Enamine/imine deaminase; Allergen Der f 34.0101; EC 3.5.99.10 from Dermatophagoides farinae (American house dust mite) (see paper)
33% identity, 68% coverage: 21:114/138 of query aligns to 19:113/128 of A0A1J1DL12

query
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A0A1J1DL12

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Y19 (= Y21) mutation to A: Loss of imine deaminase activity; when associated with A-33; A-59; A-91; A-105; A-114 and A-120.
G33 (= G35) mutation to A: Loss of imine deaminase activity; when associated with A-19; A-59; A-91; A-105; A-114 and A-120.
N59 (= N59) mutation to A: Loss of imine deaminase activity; when associated with A-19; A-33; A-91; A-105; A-114 and A-120.
N91 (≠ I91) mutation to A: Loss of imine deaminase activity; when associated with A-19; A-33; A-59; A-105; A-114 and A-120.
R105 (≠ W106) mutation to A: Loss of imine deaminase activity; when associated with A-19; A-33; A-59; A-91; A-114 and A-120.

Sites not aligning to the query:

1 modified: Initiator methionine, Removed
114 P→A: Loss of imine deaminase activity; when associated with A-19; A-33; A-59; A-91; A-105 and A-120.
120 E→A: Loss of imine deaminase activity; when associated with A-19; A-33; A-59; A-91; A-105 and A-114.

2b33B Crystal structure of a putative endoribonuclease (tm0215) from thermotoga maritima msb8 at 2.30 a resolution
36% identity, 78% coverage: 21:128/138 of query aligns to 16:122/126 of 2b33B

query
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2b33B

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binding calcium ion: D35 (≠ G40), E37 (≠ D42)

5v4dA Crystal structure of the protein of unknown function of the conserved rid protein family yyfa from yersinia pestis
33% identity, 78% coverage: 21:128/138 of query aligns to 18:125/127 of 5v4dA

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binding calcium ion: D91 (≠ K92), D95 (≠ R96)

P52759 2-iminobutanoate/2-iminopropanoate deaminase; Liver perchloric acid-soluble protein; L-PSP; Reactive intermediate imine deaminase A homolog; Translation inhibitor L-PSP ribonuclease; UK114 antigen homolog; rp14.5; EC 3.5.99.10 from Rattus norvegicus (Rat) (see paper)
34% identity, 81% coverage: 21:132/138 of query aligns to 21:131/137 of P52759

query
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P52759

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Sites not aligning to the query:

1 modified: Initiator methionine, Removed
2 modified: N-acetylserine

7cd4A Crystal structure of the s103f mutant of bacillus subtilis (natto) yabj protein. (see paper)
33% identity, 59% coverage: 21:102/138 of query aligns to 16:99/124 of 7cd4A

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binding zinc ion: E47 (≠ A51)

Sites not aligning to the query:

binding zinc ion: 5, 8

P80601 2-iminobutanoate/2-iminopropanoate deaminase; 14.3 kDa perchloric acid soluble protein; Translation inhibitor L-PSP ribonuclease; UK114 antigen; EC 3.5.99.10; EC 3.1.-.- from Capra hircus (Goat) (see paper)
31% identity, 78% coverage: 21:128/138 of query aligns to 21:127/137 of P80601

query
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P80601

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Sites not aligning to the query:

1 modified: Initiator methionine, Removed
2 modified: N-acetylserine

3vczB 1.80 angstrom resolution crystal structure of a putative translation initiation inhibitor from vibrio vulnificus cmcp6
31% identity, 78% coverage: 21:128/138 of query aligns to 16:125/127 of 3vczB

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binding magnesium ion: D79 (= D83), N81 (≠ R85)

2uynA Crystal structure of e. Coli tdcf with bound 2-ketobutyrate (see paper)
27% identity, 59% coverage: 21:101/138 of query aligns to 16:97/127 of 2uynA

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binding 2-ketobutyric acid: F83 (≠ L87)

Sites not aligning to the query:

binding 2-ketobutyric acid: 104, 105, 106

2uykC Crystal structure of e. Coli tdcf with bound serine (see paper)
27% identity, 59% coverage: 21:101/138 of query aligns to 16:97/127 of 2uykC

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Sites not aligning to the query:

binding serine: 104, 105, 106

P0AFQ5 3-aminoacrylate deaminase RutC; 3-AA deaminase; EC 3.5.-.- from Escherichia coli (strain K12) (see paper)
25% identity, 92% coverage: 4:130/138 of query aligns to 3:126/128 of P0AFQ5

query
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P0AFQ5

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R104 (≠ W106) mutation to A: Loss of activity.

Query Sequence

>HSERO_RS06570 FitnessBrowser__HerbieS:HSERO_RS06570
MSDRQAIIPKGMEDVYEKIGYAPAVRVGQVLYVSGQIGRGPDMQLVEPREAQIVQAFENL
KLVLATAGGTLDDIVDLTTFHTDMRDLPLFIKVRNRYLSHYPLPAWTAIGAHMLGGAPGY
VIEIKAVAHLRPAGGGAS

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory