Comparing HSERO_RS07545 FitnessBrowser__HerbieS:HSERO_RS07545 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
1v1bA 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound atp (see paper)
38% identity, 98% coverage: 5:310/313 of query aligns to 2:298/300 of 1v1bA
Q53W83 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
38% identity, 98% coverage: 5:310/313 of query aligns to 2:298/309 of Q53W83
1v1aA 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound 2- keto-3-deoxygluconate and adp (see paper)
38% identity, 98% coverage: 5:310/313 of query aligns to 2:298/301 of 1v1aA
Q97U29 2-dehydro-3-deoxygluconokinase/2-dehydro-3-deoxygalactonokinase; 2-dehydro-3-deoxyglucono/galactono-kinase; 2-keto-3-deoxy-galactonokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; KDGal kinase; EC 2.7.1.178 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
32% identity, 98% coverage: 5:310/313 of query aligns to 2:305/313 of Q97U29
2varA Crystal structure of sulfolobus solfataricus 2-keto-3-deoxygluconate kinase complexed with 2-keto-3-deoxygluconate (see paper)
32% identity, 98% coverage: 5:310/313 of query aligns to 1:304/311 of 2varA
2dcnA Crystal structure of 2-keto-3-deoxygluconate kinase from sulfolobus tokodaii complexed with 2-keto-6-phosphogluconate (alpha-furanose form)
28% identity, 97% coverage: 7:311/313 of query aligns to 3:303/308 of 2dcnA
3in1A Crystal structure of a putative ribokinase in complex with adp from e.Coli
30% identity, 98% coverage: 4:310/313 of query aligns to 1:305/312 of 3in1A
5eynA Crystal structure of fructokinase from vibrio cholerae o395 in fructose, adp, beryllium trifluoride and calcium ion bound form
33% identity, 90% coverage: 29:311/313 of query aligns to 20:303/306 of 5eynA
Sites not aligning to the query:
5yggA Crystal structure of fructokinase double-mutant (t261c-h108c) from vibrio cholerae o395 in fructose, adp and potassium ion bound form (see paper)
33% identity, 90% coverage: 29:311/313 of query aligns to 24:307/310 of 5yggA
Sites not aligning to the query:
3iq0B Crystal structure of a putative ribokinase ii in complex with atp and mg+2 from e.Coli
31% identity, 97% coverage: 7:311/313 of query aligns to 4:303/308 of 3iq0B
Q8ZKR2 Aminoimidazole riboside kinase; AIRs kinase; EC 2.7.1.223 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
26% identity, 91% coverage: 26:310/313 of query aligns to 20:304/319 of Q8ZKR2
Sites not aligning to the query:
3ih0A Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with amp-pnp
29% identity, 85% coverage: 7:273/313 of query aligns to 3:256/304 of 3ih0A
Sites not aligning to the query:
3gbuA Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with atp
29% identity, 85% coverage: 7:273/313 of query aligns to 2:255/302 of 3gbuA
Sites not aligning to the query:
1tz6A Crystal structure of aminoimidazole riboside kinase from salmonella enterica complexed with aminoimidazole riboside and atp analog (see paper)
26% identity, 91% coverage: 26:310/313 of query aligns to 16:293/297 of 1tz6A
Sites not aligning to the query:
1tz3A Crystal structure of aminoimidazole riboside kinase complexed with aminoimidazole riboside (see paper)
26% identity, 91% coverage: 26:310/313 of query aligns to 16:293/299 of 1tz3A
Sites not aligning to the query:
4xckA Vibrio cholerae o395 ribokinase complexed with adp, ribose and cesium ion. (see paper)
28% identity, 88% coverage: 37:311/313 of query aligns to 39:300/306 of 4xckA
Sites not aligning to the query:
7fcaD Pfkb(mycobacterium marinum) (see paper)
29% identity, 85% coverage: 11:275/313 of query aligns to 8:242/282 of 7fcaD
4ebuA Crystal structure of a sugar kinase (target efi-502312) from oceanicola granulosus, with bound amp/adp crystal form i
30% identity, 88% coverage: 5:279/313 of query aligns to 15:282/306 of 4ebuA
Sites not aligning to the query:
4eumA Crystal structure of a sugar kinase (target efi-502132) from oceanicola granulosus with bound amp, crystal form ii
30% identity, 88% coverage: 5:279/313 of query aligns to 15:278/294 of 4eumA
Sites not aligning to the query:
6wk0B Crystal structure of human ribokinase in complex with amppcp and ribose
27% identity, 86% coverage: 41:309/313 of query aligns to 44:304/311 of 6wk0B
Sites not aligning to the query:
>HSERO_RS07545 FitnessBrowser__HerbieS:HSERO_RS07545
MTMQLDVVTWGEALALLVADEVGPFEEVEKYTRRLAGAETNVAIGLARLGLKVGWASRVG
NDAFGRFIRQRVAQEGVEVSRVITDMEFRTAIQLKAKAVGGADPAIEYYRKGSAASHLSV
DDFDAGYFGAARHLHATGIAPALSATTMAFAHQAMDFMRGQGKTISFDPNLRPMLWPSQE
VMAQQLNALAFKADWVLPGLSEGKILTGHDDAREIAGFYLERGVKLVVIKLGAEGAYWRN
GQGEGRVAGVPVKEVVDTVGAGDGFAVGVISGMLEGLPVPQAVMRGNRIGAFAIQVVGDM
EGLPTRAELEAAS
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory