Comparing HSERO_RS08580 FitnessBrowser__HerbieS:HSERO_RS08580 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
6ib8B Structure of a complex of suhb and nusa ar2 domain (see paper)
48% identity, 100% coverage: 1:265/265 of query aligns to 3:266/270 of 6ib8B
P0ADG4 Nus factor SuhB; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.25 from Escherichia coli (strain K12) (see 5 papers)
48% identity, 98% coverage: 5:265/265 of query aligns to 3:262/267 of P0ADG4
2qflA Structure of suhb: inositol monophosphatase and extragenic suppressor from e. Coli (see paper)
48% identity, 98% coverage: 5:265/265 of query aligns to 3:262/262 of 2qflA
6tqoT Rrn anti-termination complex (see paper)
47% identity, 98% coverage: 5:265/265 of query aligns to 3:254/255 of 6tqoT
3lv0A Crystal structure of extragenic suppressor protein suhb from bartonella henselae, native
44% identity, 94% coverage: 6:253/265 of query aligns to 3:246/258 of 3lv0A
3luzA Crystal structure of extragenic suppressor protein suhb from bartonella henselae, via combined iodide sad molecular replacement (see paper)
45% identity, 81% coverage: 40:253/265 of query aligns to 25:228/238 of 3luzA
Sites not aligning to the query:
3luzB Crystal structure of extragenic suppressor protein suhb from bartonella henselae, via combined iodide sad molecular replacement (see paper)
44% identity, 82% coverage: 36:253/265 of query aligns to 22:224/234 of 3luzB
Sites not aligning to the query:
Q9M8S8 Inositol-phosphate phosphatase; L-galactose 1-phosphate phosphatase; Myo-inositol monophosphatase; EC 3.1.3.25; EC 3.1.3.93 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
43% identity, 75% coverage: 33:231/265 of query aligns to 35:236/271 of Q9M8S8
2p3nA Thermotoga maritima impase tm1415 (see paper)
39% identity, 76% coverage: 35:236/265 of query aligns to 31:221/256 of 2p3nA
O33832 Fructose-1,6-bisphosphatase/inositol-1-monophosphatase; FBPase/IMPase; Inositol-1-phosphatase; I-1-Pase; EC 3.1.3.11; EC 3.1.3.25 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
39% identity, 76% coverage: 35:236/265 of query aligns to 31:221/256 of O33832
O14732 Inositol monophosphatase 2; IMP 2; IMPase 2; Inositol-1(or 4)-monophosphatase 2; Myo-inositol monophosphatase A2; EC 3.1.3.25 from Homo sapiens (Human) (see 2 papers)
35% identity, 95% coverage: 6:258/265 of query aligns to 19:273/288 of O14732
2cziA Crystal structure of human myo-inositol monophosphatase 2 (impa2) with calcium and phosphate ions (see paper)
35% identity, 95% coverage: 6:258/265 of query aligns to 5:250/259 of 2cziA
1imdA Structural studies of metal binding by inositol monophosphatase: evidence for two-metal ion catalysis (see paper)
34% identity, 95% coverage: 7:258/265 of query aligns to 5:258/266 of 1imdA
2hhmA Structure of inositol monophosphatase, the putative target of lithium therapy (see paper)
34% identity, 95% coverage: 7:258/265 of query aligns to 5:258/272 of 2hhmA
1imbA Structural analysis of inositol monophosphatase complexes with substrates (see paper)
34% identity, 95% coverage: 7:258/265 of query aligns to 5:258/272 of 1imbA
1awbA Human myo-inositol monophosphatase in complex with d-inositol-1- phosphate and calcium
34% identity, 95% coverage: 7:258/265 of query aligns to 5:258/272 of 1awbA
6zk0AAA human impase with ebselen (see paper)
34% identity, 95% coverage: 7:258/265 of query aligns to 6:259/274 of 6zk0AAA
4as4A Structure of human inositol monophosphatase 1 (see paper)
34% identity, 95% coverage: 7:258/265 of query aligns to 7:260/274 of 4as4A
6giuA Human impase with l-690330 (see paper)
34% identity, 95% coverage: 7:258/265 of query aligns to 7:260/275 of 6giuA
P29218 Inositol monophosphatase 1; IMP 1; IMPase 1; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; EC 3.1.3.25; EC 3.1.3.94 from Homo sapiens (Human) (see 5 papers)
34% identity, 95% coverage: 7:258/265 of query aligns to 9:262/277 of P29218
>HSERO_RS08580 FitnessBrowser__HerbieS:HSERO_RS08580
MIIPPMLNTAIKAARRAATIINRASFDVSLLKVSKKSHNDFVTEVDKAAEDAIIDVLKNA
YPDHAILAEESGASDNLHDENENVWIIDPLDGTTNFIHGFPQYCVSIALQQRGIITQAVV
YDPTRNDLFTASKGAGAYLNEKRIRVGKRDKIADALIGTGFPFRDLDGLNEYVKMFKVMT
EHSAGLRRPGAAALDLAYVAAGRLDGFFEKGLKPWDIAAGSLLVTEAGGIVGTFKGDSDY
LYKGDVIAASPKIFAQQVNLLSEFA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory