Comparing HSERO_RS17120 FitnessBrowser__HerbieS:HSERO_RS17120 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8ewoA Crystal structure of putative glyoxylase ii from pseudomonas aeruginosa
50% identity, 100% coverage: 1:263/264 of query aligns to 3:259/259 of 8ewoA
6rz0A Crystal structure of escherichia coli glyoxalase ii
45% identity, 100% coverage: 1:263/264 of query aligns to 1:251/251 of 6rz0A
Q9SID3 Hydroxyacylglutathione hydrolase 2, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
39% identity, 100% coverage: 1:263/264 of query aligns to 71:324/324 of Q9SID3
2q42A Ensemble refinement of the protein crystal structure of glyoxalase ii from arabidopsis thaliana gene at2g31350 (see paper)
40% identity, 98% coverage: 6:263/264 of query aligns to 6:254/254 of 2q42A
2qedA Crystal structure of salmonella thyphimurium lt2 glyoxalase ii (see paper)
42% identity, 100% coverage: 1:263/264 of query aligns to 2:252/252 of 2qedA
Q8ZRM2 Hydroxyacylglutathione hydrolase; Glyoxalase II; Glx II; EC 3.1.2.6 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
42% identity, 100% coverage: 1:263/264 of query aligns to 1:251/251 of Q8ZRM2
O24496 Hydroxyacylglutathione hydrolase cytoplasmic; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
38% identity, 95% coverage: 1:252/264 of query aligns to 1:251/258 of O24496
1qh5B Human glyoxalase ii with s-(n-hydroxy-n-bromophenylcarbamoyl) glutathione (see paper)
38% identity, 100% coverage: 1:264/264 of query aligns to 1:256/260 of 1qh5B
1qh5A Human glyoxalase ii with s-(n-hydroxy-n-bromophenylcarbamoyl) glutathione (see paper)
38% identity, 100% coverage: 1:264/264 of query aligns to 1:256/260 of 1qh5A
1qh3A Human glyoxalase ii with cacodylate and acetate ions present in the active site (see paper)
38% identity, 100% coverage: 1:264/264 of query aligns to 1:256/260 of 1qh3A
Q16775 Hydroxyacylglutathione hydrolase, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Homo sapiens (Human) (see paper)
38% identity, 100% coverage: 1:264/264 of query aligns to 49:304/308 of Q16775
2p18A Crystal structure of the leishmania infantum glyoxalase ii (see paper)
29% identity, 92% coverage: 1:242/264 of query aligns to 13:272/283 of 2p18A
2zwrB Crystal structure of ttha1623 from thermus thermophilus hb8 (see paper)
33% identity, 83% coverage: 15:233/264 of query aligns to 16:206/207 of 2zwrB
2zziA Crystal structure of ttha1623 in a di-iron-bound form (see paper)
37% identity, 61% coverage: 15:175/264 of query aligns to 14:182/198 of 2zziA
2xf4A Crystal structure of salmonella enterica serovar typhimurium ycbl (see paper)
34% identity, 69% coverage: 3:184/264 of query aligns to 5:200/210 of 2xf4A
7ev5A Crystal structure of bleg-1 b3 metallo-beta-lactamase (see paper)
31% identity, 62% coverage: 12:175/264 of query aligns to 13:191/209 of 7ev5A
7l0bA Crystal structure of hydroxyacyl glutathione hydrolase (glob) from staphylococcus aureus, apoenzyme (see paper)
28% identity, 63% coverage: 11:175/264 of query aligns to 13:185/202 of 7l0bA
O95571 Persulfide dioxygenase ETHE1, mitochondrial; Ethylmalonic encephalopathy protein 1; Hepatoma subtracted clone one protein; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Homo sapiens (Human) (see 4 papers)
32% identity, 63% coverage: 12:177/264 of query aligns to 37:197/254 of O95571
Sites not aligning to the query:
Q9C8L4 Persulfide dioxygenase ETHE1 homolog, mitochondrial; Glyoxalase II; Glx II; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
31% identity, 61% coverage: 16:177/264 of query aligns to 72:234/294 of Q9C8L4
4chlB Human ethylmalonic encephalopathy protein 1 (hethe1) (see paper)
32% identity, 63% coverage: 12:177/264 of query aligns to 21:181/237 of 4chlB
>HSERO_RS17120 FitnessBrowser__HerbieS:HSERO_RS17120
LDVLAVPAFDDNYLWIIHDGRYAAVVDPGDAVPVLAALQAEGLTLAAILLTHHHADHVGG
VVELARQAASDTFPIIPVYGPAREQSRIKGMTVPLHGNDQVDIAVLGLRLEVIEVPGHTM
GHIAYHAPEQAMLFCGDTLFAGGCGRLFEGTPQQMVDSLSRLASLPGQTAVYCAHEYTLS
NLKFAAEVEPGNAELHARITRERARRERGEPTVPTSIALERQTNPFLRATEKEILDSLQK
AGRLKELDEVSSFAALREWKNSYK
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory