Comparing HSERO_RS17130 FitnessBrowser__HerbieS:HSERO_RS17130 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8j5qD Cryo-em structure of mycobacterium tuberculosis oppabcd in the pre- translocation state (see paper)
40% identity, 98% coverage: 5:521/529 of query aligns to 3:601/611 of 8j5qD
8j5tD Cryo-em structure of mycobacterium tuberculosis oppabcd in the catalytic intermediate state (see paper)
40% identity, 98% coverage: 5:521/529 of query aligns to 3:601/608 of 8j5tD
8j5sD Cryo-em structure of mycobacterium tuberculosis oppabcd in the pre- catalytic intermediate state (see paper)
40% identity, 98% coverage: 5:521/529 of query aligns to 3:601/608 of 8j5sD
P0AAH4 Putrescine export system ATP-binding protein SapD from Escherichia coli (strain K12) (see paper)
39% identity, 48% coverage: 5:259/529 of query aligns to 3:268/330 of P0AAH4
7z18I E. Coli c-p lyase bound to a phnk abc dimer and atp (see paper)
37% identity, 47% coverage: 5:252/529 of query aligns to 3:246/250 of 7z18I
7z15I E. Coli c-p lyase bound to a phnk/phnl dual abc dimer and adp + pi (see paper)
37% identity, 47% coverage: 5:252/529 of query aligns to 3:246/253 of 7z15I
7z16I E. Coli c-p lyase bound to phnk/phnl dual abc dimer with amppnp and phnk e171q mutation (see paper)
37% identity, 47% coverage: 5:252/529 of query aligns to 3:246/250 of 7z16I
4u00A Crystal structure of ttha1159 in complex with adp (see paper)
35% identity, 47% coverage: 5:251/529 of query aligns to 2:237/241 of 4u00A
P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 3 papers)
33% identity, 51% coverage: 5:272/529 of query aligns to 1:260/343 of P30750
Sites not aligning to the query:
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form (see paper)
32% identity, 51% coverage: 5:272/529 of query aligns to 2:261/344 of 3tuzC
Sites not aligning to the query:
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form (see paper)
32% identity, 51% coverage: 5:272/529 of query aligns to 2:261/344 of 3tuiC
6cvlD Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
32% identity, 51% coverage: 5:272/529 of query aligns to 2:261/344 of 6cvlD
Q8RDH4 Dipeptide transport ATP-binding protein DppD; EC 7.4.2.9 from Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis) (see paper)
35% identity, 48% coverage: 267:519/529 of query aligns to 3:255/326 of Q8RDH4
Sites not aligning to the query:
4fwiB Crystal structure of the nucleotide-binding domain of a dipeptide abc transporter (see paper)
35% identity, 48% coverage: 267:519/529 of query aligns to 2:254/310 of 4fwiB
Sites not aligning to the query:
3c4jA Abc protein artp in complex with atp-gamma-s
35% identity, 47% coverage: 5:250/529 of query aligns to 3:238/242 of 3c4jA
3c41J Abc protein artp in complex with amp-pnp/mg2+
35% identity, 47% coverage: 5:250/529 of query aligns to 3:238/242 of 3c41J
2olkA Abc protein artp in complex with adp-beta-s
35% identity, 47% coverage: 5:250/529 of query aligns to 3:238/242 of 2olkA
2oljA Abc protein artp in complex with adp/mg2+
35% identity, 47% coverage: 5:250/529 of query aligns to 3:238/242 of 2oljA
4ymuJ Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
33% identity, 44% coverage: 289:520/529 of query aligns to 13:237/240 of 4ymuJ
Sites not aligning to the query:
7ahhC Opua inhibited inward-facing, sbd docked (see paper)
33% identity, 42% coverage: 297:519/529 of query aligns to 46:263/382 of 7ahhC
Sites not aligning to the query:
>HSERO_RS17130 FitnessBrowser__HerbieS:HSERO_RS17130
MSAALLEVNNLTVRFGDTVVVDRVSFAIAPGEKFALVGESGSGKTVSSLAVMQLNQDARY
EGSILLDGQDVLAKSERQMQQVRGNDVAMIFQEPMTALNPLFTIGNQIAEVLMHHEGLNA
RDAARRAVALLEKTGIPEPARRALSYPHELSGGQRQRAMIAMALACKPKLLIADEPTTAL
DVTIQVQILALLNQLQREENMAVLIISHDLNLVRHFADRVGVMEKGKLVESASVAELFAN
PQQPYTRKLLQSRPQRNAADVAADAPVVLQAERLRCTYHIKQGWFAKRAFHAVDGVDLQL
RRGETLGIVGESGSGKSTLGMALLRLSAASVAGSIRFDGVPISERPQRELRPLRSRMQVV
FQDPFASLSPRRTVEQIVGEGLELHHPDRSAEQQRQAIVAALEEVGLSAAVLERYPHEFS
GGQRQRIAIARALVLQPELLLLDEPTSALDVTVQQQVLQLLAELQRRHGLAYLFITHDLA
VVQAMAHQVIVMKDGKVVESGATAQVLQQPQQEYTRRLVAAATYAEAAP
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory