Comparing HSERO_RS18430 FitnessBrowser__HerbieS:HSERO_RS18430 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 15 hits to proteins with known functional sites (download)
P0A9J8 Bifunctional chorismate mutase/prephenate dehydratase; Chorismate mutase-prephenate dehydratase; P-protein; EC 5.4.99.5; EC 4.2.1.51 from Escherichia coli (strain K12)
33% identity, 99% coverage: 2:354/357 of query aligns to 3:376/386 of P0A9J8
2qmxA The crystal structure of l-phe inhibited prephenate dehydratase from chlorobium tepidum tls (see paper)
39% identity, 74% coverage: 90:353/357 of query aligns to 3:273/278 of 2qmxA
3mwbA The crystal structure of prephenate dehydratase in complex with l-phe from arthrobacter aurescens to 2.0a
34% identity, 74% coverage: 89:353/357 of query aligns to 1:274/306 of 3mwbA
3mwbB The crystal structure of prephenate dehydratase in complex with l-phe from arthrobacter aurescens to 2.0a
34% identity, 74% coverage: 89:353/357 of query aligns to 1:271/303 of 3mwbB
6vh5D Crystal structure of prephenate dehydratase from brucella melitensis biovar abortus 2308 in complex with phenylalanine
32% identity, 74% coverage: 91:353/357 of query aligns to 9:276/282 of 6vh5D
7am0B Gqqa- a novel type of quorum quenching acylases (see paper)
30% identity, 74% coverage: 90:354/357 of query aligns to 3:270/278 of 7am0B
3luyA Putative chorismate mutase from bifidobacterium adolescentis
30% identity, 73% coverage: 93:354/357 of query aligns to 8:284/326 of 3luyA
P39912 Protein AroA(G); EC 2.5.1.54; EC 5.4.99.5 from Bacillus subtilis (strain 168) (see paper)
38% identity, 24% coverage: 1:87/357 of query aligns to 1:87/358 of P39912
5j6fA Crystal structure of dah7ps-cm complex from geobacillus sp. With prephenate (see paper)
33% identity, 24% coverage: 3:87/357 of query aligns to 1:85/352 of 5j6fA
Sites not aligning to the query:
5gmuB Crystal structure of chorismate mutase like domain of bifunctional dahp synthase of bacillus subtilis in complex with chlorogenic acid (see paper)
37% identity, 24% coverage: 2:87/357 of query aligns to 1:86/87 of 5gmuB
7alzA Gqqa- a novel type of quorum quenching acylases (see paper)
37% identity, 32% coverage: 242:354/357 of query aligns to 72:186/194 of 7alzA
6al9B Crystal structure of chorismate mutase from helicobacter pylori in complex with prephenate
31% identity, 25% coverage: 3:90/357 of query aligns to 2:87/91 of 6al9B
6al9A Crystal structure of chorismate mutase from helicobacter pylori in complex with prephenate
31% identity, 25% coverage: 3:90/357 of query aligns to 1:86/90 of 6al9A
3nvtA 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e (see paper)
30% identity, 22% coverage: 9:87/357 of query aligns to 2:75/345 of 3nvtA
Sites not aligning to the query:
3tfcA 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e in complex with phosphoenolpyruvate (see paper)
30% identity, 22% coverage: 9:87/357 of query aligns to 1:74/343 of 3tfcA
Sites not aligning to the query:
>HSERO_RS18430 FitnessBrowser__HerbieS:HSERO_RS18430
MSDDKLLPLRQKIDAIDAQILDLLNQRARVAQEVGHVKAETNAPVFRPEREAQVLRRAAD
RNPGPLLGADIQTIFREVMSACRALEKRVVVAYLGPEGTFSEQAVYQQFGHAIEGLSCVS
IDEVFRDAEAGTADFGVVPIENSSEGVINRTLDLLLQTTLTISGEVSIPVHHSLMTASGK
MEGITRICAHSQALAQCNAWLNQNYPSIERQAVASNAEAARMAGEDQSVAAIAGEIAGQK
YNLQTVNAHIQDDPHNRTRFAVIGRLRTAPSGRDQTSIVLSVPNKAGAVYNLLAPLARHG
VSMTRFESRPARMGAWEYYFYVDLEGHEQDEKVAQALEELRQNAAFFKLLGSYPLGL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory