Comparing HSERO_RS18575 FitnessBrowser__HerbieS:HSERO_RS18575 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
Q5PXQ6 Hydroxyquinol 1,2-dioxygenase; 1,2-HQD; EC 1.13.11.37 from Nocardioides simplex (Arthrobacter simplex) (see paper)
49% identity, 97% coverage: 6:285/288 of query aligns to 13:292/293 of Q5PXQ6
1tmxA Crystal structure of hydroxyquinol 1,2-dioxygenase from nocardioides simplex 3e (see paper)
49% identity, 97% coverage: 6:285/288 of query aligns to 12:291/292 of 1tmxA
3n9tA Cryatal structure of hydroxyquinol 1,2-dioxygenase from pseudomonas putida dll-e4
48% identity, 90% coverage: 24:283/288 of query aligns to 23:283/286 of 3n9tA
3th1A Crystal structure of chlorocatechol 1,2-dioxygenase from pseudomonas putida
33% identity, 81% coverage: 22:254/288 of query aligns to 2:227/246 of 3th1A
1dmhA Structure of catechol 1,2-dioxygenase from acinetobacter sp. Adp1 with bound 4-methylcatechol (see paper)
29% identity, 91% coverage: 24:286/288 of query aligns to 27:293/309 of 1dmhA
1dltA Structure of catechol 1,2-dioxygenase from acinetobacter sp. Adp1 with bound catechol (see paper)
29% identity, 91% coverage: 24:286/288 of query aligns to 27:293/309 of 1dltA
1dlmA Structure of catechol 1,2-dioxygenase from acinetobacter calcoaceticus native data (see paper)
29% identity, 91% coverage: 24:286/288 of query aligns to 27:293/309 of 1dlmA
P07773 Catechol 1,2-dioxygenase; 1,2-CTD; EC 1.13.11.1 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
29% identity, 91% coverage: 24:286/288 of query aligns to 29:295/311 of P07773
3hj8A Crystal structure determination of catechol 1,2-dioxygenase from rhodococcus opacus 1cp in complex with 4-chlorocatechol (see paper)
35% identity, 66% coverage: 96:285/288 of query aligns to 75:256/257 of 3hj8A
Sites not aligning to the query:
3i51A Crystal structure determination of catechol 1,2-dioxygenase from rhodococcus opacus 1cp in complex with 4,5-dichlorocatechol (see paper)
35% identity, 66% coverage: 96:285/288 of query aligns to 74:255/256 of 3i51A
Sites not aligning to the query:
3i4yA Crystal structure determination of catechol 1,2-dioxygenase from rhodococcus opacus 1cp in complex with 3,5-dichlorocatechol (see paper)
35% identity, 66% coverage: 96:285/288 of query aligns to 74:255/256 of 3i4yA
Sites not aligning to the query:
3i4vA Crystal structure determination of catechol 1,2-dioxygenase from rhodococcus opacus 1cp in complex with 3-chlorocatechol (see paper)
35% identity, 66% coverage: 96:285/288 of query aligns to 74:255/256 of 3i4vA
3hjsA Crystal structure of catechol 1,2-dioxygenase from rhodococcus opacus 1cp in complex with 4-methylcatechol (see paper)
35% identity, 66% coverage: 96:285/288 of query aligns to 74:255/256 of 3hjsA
Sites not aligning to the query:
3hjqA Crystal structure of catechol 1,2-dioxygenase from rhodococcus opacus 1cp in complex with 3-methylcatechol (see paper)
35% identity, 66% coverage: 96:285/288 of query aligns to 74:255/256 of 3hjqA
Sites not aligning to the query:
3hhyA Crystal structure determination of catechol 1,2-dioxygenase from rhodococcus opacus 1cp in complex with catechol (see paper)
35% identity, 66% coverage: 96:285/288 of query aligns to 74:255/256 of 3hhyA
Sites not aligning to the query:
3hhxA Crystal structure determination of catechol 1,2-dioxygenase from rhodococcus opacus 1cp in complex with pyrogallol (see paper)
35% identity, 66% coverage: 96:285/288 of query aligns to 74:255/256 of 3hhxA
Sites not aligning to the query:
3hgiA Crystal structure of catechol 1,2-dioxygenase from the gram-positive rhodococcus opacus 1cp (see paper)
35% identity, 66% coverage: 96:285/288 of query aligns to 76:257/258 of 3hgiA
2azqA Crystal structure of catechol 1,2-dioxygenase from pseudomonas arvilla c-1 (see paper)
33% identity, 91% coverage: 24:284/288 of query aligns to 27:289/309 of 2azqA
2boyA Crystal structure of 3-chlorocatechol 1,2-dioxygenase from rhodococcus opacus 1cp (see paper)
30% identity, 80% coverage: 24:253/288 of query aligns to 4:228/253 of 2boyA
5umhB Crystal structure of catechol 1,2-dioxygenase protein from burkholderia multivorans
31% identity, 92% coverage: 22:286/288 of query aligns to 26:292/310 of 5umhB
>HSERO_RS18575 FitnessBrowser__HerbieS:HSERO_RS18575
MLNLNEDTITQAVLSRHAWLTDQRLREIMTSLVQHLHAFAREVKLTEKEWFAGIDFLTET
GQICSDQRQEFILLSDTLGLSTLVMAQQNHKPAGCTEATVFGPFHVEDAPQYPLGADIAN
GAKGEPCFVSGSVRGRNGRPLAHARMEVWQADENGFYDVQYADLDQYRARGTLFTDAEGR
YHFRSILANPYPIPHDGPVGRMLEKLGRHPWRPAHLHFRIQAEGYETLITHVFRRDDVYL
DSDAVFGVRSTLIADWPCHPAGTAPDGTQCEQPFYTLDYDFVLNPLRK
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory