Comparing HSERO_RS19370 FitnessBrowser__HerbieS:HSERO_RS19370 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 17 hits to proteins with known functional sites (download)
7pldB Caulobacter crescentus xylonolactonase with (r)-4-hydroxy-2- pyrrolidone (see paper)
36% identity, 98% coverage: 7:301/302 of query aligns to 1:287/289 of 7pldB
7plbB Caulobacter crescentus xylonolactonase with d-xylose (see paper)
36% identity, 98% coverage: 7:301/302 of query aligns to 1:287/289 of 7plbB
Q9A9Z1 D-xylonolactone lactonase; Xylono-1,5-lactonase; EC 3.1.1.110 from Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus) (see paper)
36% identity, 97% coverage: 8:301/302 of query aligns to 2:287/289 of Q9A9Z1
4gnaA Mouse smp30/gnl-xylitol complex (see paper)
32% identity, 97% coverage: 8:300/302 of query aligns to 1:295/297 of 4gnaA
4gn9A Mouse smp30/gnl-glucose complex (see paper)
32% identity, 97% coverage: 8:300/302 of query aligns to 1:295/297 of 4gn9A
4gn8A Mouse smp30/gnl-1,5-ag complex (see paper)
32% identity, 97% coverage: 8:300/302 of query aligns to 1:295/297 of 4gn8A
4gn7A Mouse smp30/gnl (see paper)
32% identity, 97% coverage: 8:300/302 of query aligns to 1:295/297 of 4gn7A
Q15493 Regucalcin; RC; Gluconolactonase; GNL; Senescence marker protein 30; SMP-30; EC 3.1.1.17 from Homo sapiens (Human) (see 2 papers)
32% identity, 97% coverage: 7:300/302 of query aligns to 2:297/299 of Q15493
4gncA Human smp30/gnl-1,5-ag complex (see paper)
32% identity, 97% coverage: 7:300/302 of query aligns to 1:296/298 of 4gncA
3g4hA Crystal structure of human senescence marker protein-30 (zinc bound) (see paper)
32% identity, 96% coverage: 11:300/302 of query aligns to 4:295/297 of 3g4hA
5gx1A Luciferin-regenerating enzyme collected with serial synchrotron rotational crystallography with accumulated dose of 1.1 mgy (1st measurement) (see paper)
30% identity, 81% coverage: 21:266/302 of query aligns to 15:270/307 of 5gx1A
5d9bA Luciferin-regenerating enzyme solved by siras using xfel (refined against native data) (see paper)
30% identity, 81% coverage: 21:266/302 of query aligns to 15:270/307 of 5d9bA
7risA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound phosphate (see paper)
29% identity, 54% coverage: 108:271/302 of query aligns to 111:275/293 of 7risA
Sites not aligning to the query:
7rizA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound 2-hydroxyquinoline (see paper)
28% identity, 54% coverage: 108:271/302 of query aligns to 120:288/306 of 7rizA
Sites not aligning to the query:
8dk0A Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound (s)gamma- valerolactone (see paper)
26% identity, 54% coverage: 108:271/302 of query aligns to 115:275/293 of 8dk0A
Sites not aligning to the query:
8djzA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound product (see paper)
26% identity, 54% coverage: 108:271/302 of query aligns to 115:275/293 of 8djzA
Sites not aligning to the query:
8djfA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound tetrahedral intermediate (see paper)
26% identity, 54% coverage: 108:271/302 of query aligns to 115:275/293 of 8djfA
Sites not aligning to the query:
>HSERO_RS19370 FitnessBrowser__HerbieS:HSERO_RS19370
MSVPSPSAAAVTVAFPEPMLLGESPLWHAQEAALYWIDIPGKAVHRLHPESGQHKRWDLP
EEPGSIVRHAQGGLVVAIRTGMFHLNTDTGALTLLLAAPYDSSRIRFNDGRCDASGRFWC
GTIYEPRDRDGGTLYCFERNALRDAHHAVVTSNGLAFSSDQRLMYHANTPAHRINLYDYD
LATGATSNCRLLRQFDSDKSAPDYGGRPDGAAVDSQGAYWCAMFEGGRVLRLSPQGEILQ
EIRLPARCPTMVAFGGDDLRTLYITTGRNGRSPAELAQYPESGCVLAVRVDVPGQLEYSY
RP
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory