SitesBLAST – Find functional sites

 

SitesBLAST

Comparing HSERO_RS20305 FitnessBrowser__HerbieS:HSERO_RS20305 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 1 hits to proteins with known functional sites (download)

6j2lA Crystal structure of bi-functional enzyme (see paper)
37% identity, 84% coverage: 5:98/112 of query aligns to 114:200/200 of 6j2lA

query
sites
6j2lA
L
 
L
K
 
Y
R
 
Q
L
 
L
A
 
E
E
 
Q
V
 
L
I
 
L
E
 
A
S
 
E
R
 
R
K
 
K
L
 
Y
A
 
A
N
 
D
G
 
-
G
 
-
N
 
-
P
 
P
E
 
E
K
 
T
S
 
S
Y
 
Y
V
 
T
A
 
A
K
 
K
L
 
L
F
 
Y
S
 
A
K
 
S
G
 
G
D
 
T
D
 
K
A
 
R
I
 
I
L
 
A
K
 
Q
K
 
K
I
 
V
G
 
G
E
 
E
E
|
E
A
 
G
T
 
V
E
 
E
T
 
T
V
 
A
M
 
L
A
 
A
A
 
A
K
 
-
D
 
-
A
 
-
R
 
-
V
 
T
S
 
V
G
 
H
D
 
D
K
 
R
Y
 
F
K
 
E
V
 
L
L
 
T
Y
 
N
E
|
E
C
 
A
A
 
S
D
|
D
L
 
L
W
 
M
F
 
Y
H
 
H
S
 
L
M
 
L
V
 
V
L
 
L
L
 
L
A
 
Q
Q
 
D
F
 
Q
D
 
D
L
 
L
S
 
D
P
 
L
Q
 
T
D
 
T
V
 
V
L
 
I
N
 
E
E
 
N
L
 
L
A
 
H
R
 
K
R
 
R

Sites not aligning to the query:

Query Sequence

>HSERO_RS20305 FitnessBrowser__HerbieS:HSERO_RS20305
MSETLKRLAEVIESRKLANGGNPEKSYVAKLFSKGDDAILKKIGEEATETVMAAKDARVS
GDKYKVLYECADLWFHSMVLLAQFDLSPQDVLNELARREGLSGLEEKAARKD

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory