Comparing HSERO_RS20645 FitnessBrowser__HerbieS:HSERO_RS20645 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4pzeA Crystal structure of (s)-3-hydroxybutyryl-coa dehydrogenase paah1 in complex with acetoacetyl-coa (see paper)
41% identity, 55% coverage: 16:295/512 of query aligns to 5:283/283 of 4pzeA
4pzdA Crystal structure of (s)-3-hydroxybutyryl-coa dehydrogenase paah1 in complex with NAD+ (see paper)
41% identity, 55% coverage: 16:295/512 of query aligns to 5:283/283 of 4pzdA
6aa8E Crystal structure of (s)-3-hydroxybutyryl-coenzymea dehydrogenase from clostridium acetobutylicum complexed with NAD+ (see paper)
42% identity, 55% coverage: 16:295/512 of query aligns to 3:281/281 of 6aa8E
4kugA Crystal structure of 3-hydroxybutylryl-coa dehydrogenase with NAD from clostridium butyricum
41% identity, 55% coverage: 16:295/512 of query aligns to 4:282/282 of 4kugA
4kuhA Crystal structure of 3-hydroxybutylryl-coa dehydrogenase with acetoacetyl-coa from clostridium butyricum
41% identity, 54% coverage: 16:293/512 of query aligns to 4:280/280 of 4kuhA
P00348 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; HCDH; L-3-hydroxyacyl CoA dehydrogenase; Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; Short-chain 3-hydroxyacyl-CoA dehydrogenase; EC 1.1.1.35 from Sus scrofa (Pig) (see paper)
40% identity, 54% coverage: 16:293/512 of query aligns to 30:313/314 of P00348
Q16836 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; HCDH; Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; Short-chain 3-hydroxyacyl-CoA dehydrogenase; EC 1.1.1.35 from Homo sapiens (Human) (see 7 papers)
42% identity, 54% coverage: 16:293/512 of query aligns to 30:313/314 of Q16836
1f17A L-3-hydroxyacyl-coa dehydrogenase complexed with nadh (see paper)
41% identity, 54% coverage: 16:293/512 of query aligns to 7:290/293 of 1f17A
1f12A L-3-hydroxyacyl-coa dehydrogenase complexed with 3-hydroxybutyryl-coa (see paper)
41% identity, 54% coverage: 16:293/512 of query aligns to 7:290/293 of 1f12A
1f0yA L-3-hydroxyacyl-coa dehydrogenase complexed with acetoacetyl-coa and NAD+ (see paper)
41% identity, 54% coverage: 16:293/512 of query aligns to 7:290/291 of 1f0yA
P9WNP7 3-hydroxybutyryl-CoA dehydrogenase; Beta-hydroxybutyryl-CoA dehydrogenase; BHBD; EC 1.1.1.157 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
38% identity, 54% coverage: 16:293/512 of query aligns to 8:286/286 of P9WNP7
P40939 Trifunctional enzyme subunit alpha, mitochondrial; 78 kDa gastrin-binding protein; Monolysocardiolipin acyltransferase; TP-alpha; EC 2.3.1.-; EC 4.2.1.17; EC 1.1.1.211 from Homo sapiens (Human) (see 5 papers)
32% identity, 68% coverage: 16:363/512 of query aligns to 364:696/763 of P40939
Sites not aligning to the query:
6iunB Crystal structure of enoyl-coa hydratase (ech) from ralstonia eutropha h16 in complex with NAD
34% identity, 57% coverage: 16:305/512 of query aligns to 294:578/692 of 6iunB
Sites not aligning to the query:
7o4uA Structure of the alpha subunit of mycobacterium tuberculosis beta- oxidation trifunctional enzyme in complex with oxidized nicotinamide adenine dinucleotide (see paper)
35% identity, 57% coverage: 7:296/512 of query aligns to 308:601/711 of 7o4uA
4b3iA Crystal structure of mycobacterium tuberculosis fatty acid beta-oxidation complex with coenzymea bound at the hydratase active sites (see paper)
35% identity, 57% coverage: 7:296/512 of query aligns to 328:621/731 of 4b3iA
Sites not aligning to the query:
3k6jA Crystal structure of the dehydrogenase part of multifuctional enzyme 1 from c.Elegans
29% identity, 57% coverage: 16:305/512 of query aligns to 49:326/430 of 3k6jA