Comparing HSERO_RS22730 HSERO_RS22730 sugar ABC transporter substrate-binding protein to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
5dvjA Crystal structure of galactose complexed periplasmic glucose binding protein (ppgbp) from p. Putida csv86 (see paper)
35% identity, 86% coverage: 52:433/446 of query aligns to 3:388/396 of 5dvjA
5dviA High resolution crystal structure of glucose complexed periplasmic glucose binding protein (ppgbp) from p. Putida csv86 (see paper)
35% identity, 86% coverage: 52:433/446 of query aligns to 3:388/396 of 5dviA
4r2bA Crystal structure of sugar transporter oant_3817 from ochrobactrum anthropi, target efi-510528, with bound glucose
31% identity, 86% coverage: 53:435/446 of query aligns to 6:389/395 of 4r2bA
8hqqA Crystal structure of the glucose-binding protein sar11_0769 from "candidatus pelagibacter ubique" htcc1062 bound to glucose
34% identity, 82% coverage: 55:419/446 of query aligns to 6:377/398 of 8hqqA
2b3fA Thermus thermophilus glucose/galactose binding protein bound with galactose (see paper)
27% identity, 74% coverage: 54:385/446 of query aligns to 3:339/392 of 2b3fA
Sites not aligning to the query:
2b3bC Thermus thermophilus glucose/galactose binding protein with bound glucose (see paper)
27% identity, 74% coverage: 54:385/446 of query aligns to 3:339/392 of 2b3bC
Sites not aligning to the query:
2b3bA Thermus thermophilus glucose/galactose binding protein with bound glucose (see paper)
27% identity, 74% coverage: 54:385/446 of query aligns to 3:339/392 of 2b3bA
Sites not aligning to the query:
7ehqA Chitin oligosaccharide binding protein (see paper)
25% identity, 55% coverage: 49:295/446 of query aligns to 16:252/406 of 7ehqA
Sites not aligning to the query:
3oo6A Crystal structures and biochemical characterization of the bacterial solute receptor acbh reveal an unprecedented exclusive substrate preference for b-d-galactopyranose (see paper)
27% identity, 30% coverage: 157:292/446 of query aligns to 105:238/390 of 3oo6A
Sites not aligning to the query:
6preA Sbp rafe in complex with verbascose (see paper)
26% identity, 46% coverage: 96:300/446 of query aligns to 43:250/386 of 6preA
Sites not aligning to the query:
2i58A Crystal structure of rafe from streptococcus pneumoniae complexed with raffinose
26% identity, 46% coverage: 96:300/446 of query aligns to 42:249/385 of 2i58A
Sites not aligning to the query:
3vxcA Crystal structure of xylobiose-bxle complex from streptomyces thermoviolaceus opc-520
26% identity, 39% coverage: 121:294/446 of query aligns to 77:249/398 of 3vxcA
Sites not aligning to the query:
4zzeA Raffinose and panose binding protein from bifidobacterium animalis subsp. Lactis bl-04, bound with panose (see paper)
21% identity, 61% coverage: 100:369/446 of query aligns to 38:313/377 of 4zzeA
Sites not aligning to the query:
4zs9A Raffinose and panose binding protein from bifidobacterium animalis subsp. Lactis bl-04, bound with raffinose (see paper)
21% identity, 61% coverage: 100:369/446 of query aligns to 38:313/377 of 4zs9A
Sites not aligning to the query:
4zs9B Raffinose and panose binding protein from bifidobacterium animalis subsp. Lactis bl-04, bound with raffinose (see paper)
21% identity, 61% coverage: 100:369/446 of query aligns to 39:314/378 of 4zs9B
Sites not aligning to the query:
4g68A Biochemical and structural insights into xylan utilization by the thermophilic bacteriumcaldanaerobius polysaccharolyticus (see paper)
24% identity, 44% coverage: 100:294/446 of query aligns to 48:242/392 of 4g68A
Sites not aligning to the query:
7ehpA Chitin oligosaccharide binding protein (see paper)
25% identity, 48% coverage: 106:319/446 of query aligns to 57:270/397 of 7ehpA
Sites not aligning to the query:
4c1tA Structure of the xylo-oligosaccharide specific solute binding protein from bifidobacterium animalis subsp. Lactis bl-04 in complex with arabinoxylotriose (see paper)
27% identity, 46% coverage: 96:299/446 of query aligns to 47:253/396 of 4c1tA
Sites not aligning to the query:
7cy4A Crystal structure of cmd1 in apo form (see paper)
32% identity, 19% coverage: 120:204/446 of query aligns to 58:134/858 of 7cy4A
Sites not aligning to the query:
7cy5A Crystal structure of cmd1 in complex with vitamin c (see paper)
32% identity, 19% coverage: 120:204/446 of query aligns to 64:140/862 of 7cy5A
Sites not aligning to the query:
>HSERO_RS22730 HSERO_RS22730 sugar ABC transporter substrate-binding protein
MTRTKRPANARTGPARCGLAAVCLCALTLWLGGLPAQAQSPSSPVPPATATGSLQVLHWW
TSASERQAINVVVNQLAKQDIQWRDVAIPGGAGMGAAKVLKSMVLANRAPEVTQLNGVVF
GEWADLGLLLELDNVAVQGNWEKQMFPTVWSLLNNHGHVVAAPLGIHRINSLYYNVAVFK
RYNLSPPKTWDEFDQIVKKLQGSGVVPLAQSAEAWQLATLFENLALAESGPAYYRKLFVE
MSPAAYLDARMLHILKRLRALAGAMAQPVRERPWTEVARSMVSGEAAMLIMGDWAKGELN
AWGMEVDQQFGCAPAPGTGEYHLYSTDTLAMFAGNYAHQPMQETLARLTMSPAVQSEYNR
IKGSIPVLRAADPHMDRCARDSWRTFSKGPMWQAPSLVHRMATDDTTKDAIVAEVQRFFM
DRSISEEQAQKRLATIARTLSRNRND
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory