Comparing HSERO_RS22795 FitnessBrowser__HerbieS:HSERO_RS22795 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 18 hits to proteins with known functional sites (download)
A6VCX3 L-methionine sulfoximine/L-methionine sulfone acetyltransferase; Methionine derivative detoxifier A; MDDA; EC 2.3.1.- from Pseudomonas aeruginosa (strain PA7) (see paper)
64% identity, 96% coverage: 3:168/173 of query aligns to 5:172/172 of A6VCX3
2j8mA Structure of p. Aeruginosa acetyltransferase pa4866 (see paper)
64% identity, 96% coverage: 3:168/173 of query aligns to 4:171/171 of 2j8mA
2j8rA Structure of p. Aeruginosa acetyltransferase pa4866 solved in complex with l-methionine sulfoximine (see paper)
64% identity, 96% coverage: 3:168/173 of query aligns to 3:170/170 of 2j8rA
3dr8A Structure of ynca, a putative acetyltransferase from salmonella typhimurium with its cofactor acetyl-coa
60% identity, 98% coverage: 1:169/173 of query aligns to 3:171/173 of 3dr8A
Q8ZPD3 L-methionine sulfoximine/L-methionine sulfone acetyltransferase; L-amino acid N-acyltransferase; Methionine derivative detoxifier A; MDDA; EC 2.3.1.-; EC 2.3.1.- from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
60% identity, 98% coverage: 1:169/173 of query aligns to 1:169/171 of Q8ZPD3
4jwpA Crystal structure of ribosomal-protein-alanine n-acetyltransferase from brucella melitensis in complex with acetyl coa
55% identity, 94% coverage: 1:162/173 of query aligns to 4:165/165 of 4jwpA
2jlmF Structure of a putative acetyltransferase (aciad1637) from acinetobacter baylyi adp1 (see paper)
49% identity, 90% coverage: 14:168/173 of query aligns to 22:177/180 of 2jlmF
4mbuA Crystal structure of n-acetyltransferase from staphylococcus aureus mu50 (see paper)
44% identity, 92% coverage: 3:162/173 of query aligns to 5:164/165 of 4mbuA
4jxrB Crystal structure of a gnat superfamily phosphinothricin acetyltransferase (pat) from sinorhizobium meliloti in complex with accoa
40% identity, 91% coverage: 3:159/173 of query aligns to 5:162/185 of 4jxrB
5dwnA Crystal structure of phosphinothricin n-acetyltransferase from brucella ovis in complex with acetylcoa
41% identity, 96% coverage: 3:168/173 of query aligns to 6:175/181 of 5dwnA
5wphA Crystal structure of arsn, n-acetyltransferase with substrate ast from pseudomonas putida kt2440 (see paper)
36% identity, 91% coverage: 1:157/173 of query aligns to 2:157/179 of 5wphA
6m7gA Crystal structure of arsn, n-acetyltransferase with substrate phosphinothricin from pseudomonas putida kt2440 (see paper)
36% identity, 91% coverage: 1:157/173 of query aligns to 2:157/176 of 6m7gA
5t7eD Crystal structure of streptomyces hygroscopicus bialaphos resistance (bar) protein in complex with coenzyme a and l-phosphinothricin (see paper)
35% identity, 91% coverage: 3:160/173 of query aligns to 4:160/175 of 5t7eD
5t7dA Crystal structure of streptomyces hygroscopicus bialaphos resistance (bar) protein in complex with acetyl coenzyme a (see paper)
35% identity, 91% coverage: 3:160/173 of query aligns to 3:159/173 of 5t7dA
3ld2B The crystal structure of smu.2055 from streptococcus mutans ua159
23% identity, 89% coverage: 1:154/173 of query aligns to 2:150/162 of 3ld2B
3f8kA Crystal structure of protein acetyltransferase (pat) from sulfolobus solfataricus (see paper)
28% identity, 84% coverage: 1:145/173 of query aligns to 1:124/131 of 3f8kA
2ge3A Crystal structure of probable acetyltransferase from agrobacterium tumefaciens
30% identity, 62% coverage: 48:154/173 of query aligns to 50:155/164 of 2ge3A
Sites not aligning to the query:
1wwzA Crystal structure of ph1933 from pyrococcus horikoshii ot3
31% identity, 60% coverage: 37:140/173 of query aligns to 43:145/157 of 1wwzA
Sites not aligning to the query:
>HSERO_RS22795 FitnessBrowser__HerbieS:HSERO_RS22795
MQIRDAELADIAGITPIYNDAVANTTAIWNETLVDDRNREDWLTARRQSGYPVLVAVADG
KVLGYASFGDWRAFDGYRHTVEHSVYVHKDHRGEGLGRALMEALIARARALGKHVMVAGI
DASNSGSINLHKKLGFEQVGYLPQVGTKFGKWLDLAFLQLMLDGRTEPDRIGG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory