Comparing N515DRAFT_0055 FitnessBrowser__Dyella79:N515DRAFT_0055 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 10 hits to proteins with known functional sites (download)
4lhdA Crystal structure of synechocystis sp. Pcc 6803 glycine decarboxylase (p-protein), holo form with pyridoxal-5'-phosphate and glycine, closed flexible loop (see paper)
60% identity, 97% coverage: 16:944/956 of query aligns to 17:949/952 of 4lhdA
Sites not aligning to the query:
Q94B78 Glycine dehydrogenase (decarboxylating) 1, mitochondrial; Glycine cleavage system P protein 1; Glycine decarboxylase 1; Glycine decarboxylase P-protein 1; AtGLDP1; Glycine dehydrogenase (aminomethyl-transferring) 1; EC 1.4.4.2 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
54% identity, 99% coverage: 3:946/956 of query aligns to 64:1026/1037 of Q94B78
6i35A Crystal structure of human glycine decarboxylase (p-protein) bound with pyridoxyl-glycine-5'-monophosphate
54% identity, 98% coverage: 10:947/956 of query aligns to 7:953/953 of 6i35A
6i33A Crystal structure of human glycine decarboxylase (p-protein)
54% identity, 98% coverage: 10:947/956 of query aligns to 7:950/950 of 6i33A
6i34B Crystal structure of neanderthal glycine decarboxylase (p-protein)
54% identity, 98% coverage: 10:946/956 of query aligns to 5:954/954 of 6i34B
P15505 Glycine dehydrogenase (decarboxylating), mitochondrial; Glycine cleavage system P protein; Glycine decarboxylase; Glycine dehydrogenase (aminomethyl-transferring); EC 1.4.4.2 from Gallus gallus (Chicken) (see paper)
54% identity, 98% coverage: 12:951/956 of query aligns to 47:993/1004 of P15505
6i33B Crystal structure of human glycine decarboxylase (p-protein)
53% identity, 98% coverage: 10:946/956 of query aligns to 5:925/925 of 6i33B
1wyuB Crystal structure of glycine decarboxylase (p-protein) of the glycine cleavage system, in holo form (see paper)
42% identity, 40% coverage: 481:866/956 of query aligns to 46:433/473 of 1wyuB
1wyvA Crystal structure of glycine decarboxylase (p-protein) of the glycine cleavage system, in inhibitor-bound form (see paper)
38% identity, 40% coverage: 26:412/956 of query aligns to 7:399/437 of 1wyvA
1wyuA Crystal structure of glycine decarboxylase (p-protein) of the glycine cleavage system, in holo form (see paper)
38% identity, 40% coverage: 26:412/956 of query aligns to 7:399/437 of 1wyuA
>N515DRAFT_0055 FitnessBrowser__Dyella79:N515DRAFT_0055
MTQNASPSLRDLEHHEAFIERHIGPNDAEIAHMLSAIGYDSLEAMTDAIVPGQIKSAAPL
ALPPAMTEVEALAKIRAIADKNRVFRSFIGQGYYGTHTPNVILRNILENPAWYTAYTPYQ
AEISQGRMEALINFQTMVADLTGMDISNASLLDEATAAGEAMTLAKRSAKSKSNVFFVAD
DVHPQTLEVLRTRADGVDIALHVGPAADASTVDSFGVLLQYPNTYGTIHDYRAVAEAVHA
RGALVAVATDLLALTLIAAPGSWGADIVIGNSQRFGVPFGFGGPHAAYLACRDAYKRSMP
GRLIGVSVDAEGKPAYRLTLQTREQHIRREKATSNICTAQVLLAVMASMYAVYHGPDGLQ
RIARRTHRLAAILAATLRKAGLEVGGEFFDTLRITGVDADAIHAKAAGKGLNLRQIHGQC
VGISLDETTTRADVQALAGLFGAELSDIDEVDAATADALPAALLRQDAFLQHPVFNTHHS
EHELLRYMRSLADKDLAMDRTMIPLGSCTMKLNATAEMIPVTWPEFGNIHPLAPAAQTQG
YKQLIDELEAMLVECTGYDAVSLQPNSGAQGEYAGLLAIRAYHRSRGDEHRDVCLIPESA
HGTNPASAQMCGMTVVVTKCDANGNVDLEDIRAKAEKYSERLAALMITYPSTHGVFEEDV
VAICDIVHKHGGQVYTDGANMNALVGLAKPGKWGSDVSHLNLHKTFCIPHGGGGPGVGPC
AVKSHLAPFLPRTLGGEGSVGMVSAASFGSASILPISWMYITLMGQQGLRKATQVALLNA
NYIARRLASHYETLYTGRNGLVAHECILDLRPLKDATGISAEDVAKRLIDFGFHAPTLSF
PVAGTLMVEPTESESQHELDRFIDAMIQIREEIRAIEDGRLDREDNPLKHAPHTANAVAG
SEWTHAYPRELAVFPLPTLRLQKYWPPVARVDNVYGDKNVMCACIPVDAYKEEAEA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory