Comparing N515DRAFT_0361 FitnessBrowser__Dyella79:N515DRAFT_0361 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 8 hits to proteins with known functional sites (download)
3zdsA Structure of homogentisate 1,2-dioxygenase in complex with reaction intermediates of homogentisate with oxygen. (see paper)
62% identity, 98% coverage: 6:428/430 of query aligns to 3:421/425 of 3zdsA
3zdsF Structure of homogentisate 1,2-dioxygenase in complex with reaction intermediates of homogentisate with oxygen. (see paper)
62% identity, 98% coverage: 6:428/430 of query aligns to 4:422/426 of 3zdsF
3zdsC Structure of homogentisate 1,2-dioxygenase in complex with reaction intermediates of homogentisate with oxygen. (see paper)
62% identity, 98% coverage: 6:428/430 of query aligns to 4:422/426 of 3zdsC
Q88E47 Homogentisate 1,2-dioxygenase; HGDO; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase; EC 1.13.11.5 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
62% identity, 98% coverage: 6:428/430 of query aligns to 11:429/433 of Q88E47
4aq6D Substrate bound homogentisate 1,2-dioxygenase (see paper)
62% identity, 98% coverage: 6:428/430 of query aligns to 5:423/427 of 4aq6D
Q9Y041 Homogentisate 1,2-dioxygenase; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase; EC 1.13.11.5 from Caenorhabditis elegans (see paper)
55% identity, 98% coverage: 6:427/430 of query aligns to 9:433/437 of Q9Y041
Q93099 Homogentisate 1,2-dioxygenase; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase; EC 1.13.11.5 from Homo sapiens (Human) (see 13 papers)
53% identity, 99% coverage: 1:427/430 of query aligns to 1:434/445 of Q93099
1ey2A Human homogentisate dioxygenase with fe(ii) (see paper)
53% identity, 96% coverage: 6:416/430 of query aligns to 5:413/419 of 1ey2A
>N515DRAFT_0361 FitnessBrowser__Dyella79:N515DRAFT_0361
METKGYQSGFGNEFATEAVAGVLPHGQNSPQRVAHGLYAEQLSGSAFTAPRHSNRRSWLY
RIRPAAVHRPFEPRAHEHFHNRFDEAPATPNQLRWDPWPLPARPTDFVDGLVTLAGNGGP
AEQAGCGIHIYAANRSMLGRFFYDADGELLLVPQQGRLRVCTELGVLDVAPLEIAVIPRG
VRFRVELIDGEARGYVCENFGALLRLPDLGPIGANSMALPRDFLTPQAWYEDVEGDFELI
AKFQGSLWTAAIDHSPLDVVAWHGNYAPYKYDLTTYNTVGSISVDHPDPSIFTVLTSPSD
TPGTANVDFVIFPPRWLVAEHTFRPPYFHRNVASEFMGLIQGAYDAKEGGFVPGGASLHN
CMSGHGPDAASFEKASGADVSKPDHLTGTMAFMFETRKVIRPTRQALDAPQLQGSYYECW
QGIRKHFKES
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory