Comparing N515DRAFT_1229 N515DRAFT_1229 L-arabinonolactonase (EC 3.1.1.15) to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 13 hits to proteins with known functional sites (download)
7pldA Caulobacter crescentus xylonolactonase with (r)-4-hydroxy-2- pyrrolidone (see paper)
37% identity, 93% coverage: 12:290/300 of query aligns to 12:285/287 of 7pldA
Q9A9Z1 D-xylonolactone lactonase; Xylono-1,5-lactonase; EC 3.1.1.110 from Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus) (see paper)
37% identity, 93% coverage: 12:290/300 of query aligns to 14:287/289 of Q9A9Z1
7plbB Caulobacter crescentus xylonolactonase with d-xylose (see paper)
37% identity, 93% coverage: 12:290/300 of query aligns to 14:287/289 of 7plbB
4gnaA Mouse smp30/gnl-xylitol complex (see paper)
29% identity, 93% coverage: 14:291/300 of query aligns to 15:297/297 of 4gnaA
4gn9A Mouse smp30/gnl-glucose complex (see paper)
29% identity, 93% coverage: 14:291/300 of query aligns to 15:297/297 of 4gn9A
4gn8A Mouse smp30/gnl-1,5-ag complex (see paper)
29% identity, 93% coverage: 14:291/300 of query aligns to 15:297/297 of 4gn8A
4gn7A Mouse smp30/gnl (see paper)
29% identity, 93% coverage: 14:291/300 of query aligns to 15:297/297 of 4gn7A
3g4hA Crystal structure of human senescence marker protein-30 (zinc bound) (see paper)
30% identity, 93% coverage: 14:291/300 of query aligns to 15:297/297 of 3g4hA
Q15493 Regucalcin; RC; Gluconolactonase; GNL; Senescence marker protein 30; SMP-30; EC 3.1.1.17 from Homo sapiens (Human) (see 2 papers)
30% identity, 93% coverage: 14:291/300 of query aligns to 17:299/299 of Q15493
4gncA Human smp30/gnl-1,5-ag complex (see paper)
30% identity, 93% coverage: 14:291/300 of query aligns to 16:298/298 of 4gncA
Sites not aligning to the query:
5gx1A Luciferin-regenerating enzyme collected with serial synchrotron rotational crystallography with accumulated dose of 1.1 mgy (1st measurement) (see paper)
28% identity, 88% coverage: 12:275/300 of query aligns to 14:290/307 of 5gx1A
5d9bA Luciferin-regenerating enzyme solved by siras using xfel (refined against native data) (see paper)
28% identity, 88% coverage: 12:275/300 of query aligns to 14:290/307 of 5d9bA
7risA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound phosphate (see paper)
29% identity, 53% coverage: 100:259/300 of query aligns to 111:274/293 of 7risA
Sites not aligning to the query:
>N515DRAFT_1229 N515DRAFT_1229 L-arabinonolactonase (EC 3.1.1.15)
MNARVVHHPANTLGEGILWCEREQALYWTDIQAATLWRHRPADGATRSWEMPERLGCLAL
CEADGWLLLGLATRLAFFRPEDDLLLPLVSVEPDLPTRLNDGACDRQGRFVFGTLHEPAA
GETRQPIGAFYRLNADLTLERLNLPGIGISNSVAFSPDGRTMYFCDSPSRVIQCCDYGDR
CGEPRVFARVDDERGEPDGSAVDAQGCLWNAQWGLGRVVRYAPDGRVDRIVEVPATQPTR
PAFGDSPLDTLYITSARDGLSSAALATQPLAGALFAADAGASGLPEPRFRGAPPGFGRSS
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory