Comparing N515DRAFT_1252 FitnessBrowser__Dyella79:N515DRAFT_1252 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8gstC Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Pyruvate bound-form) (see paper)
56% identity, 96% coverage: 2:277/288 of query aligns to 7:278/290 of 8gstC
8gsrA Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Apo-form) (see paper)
56% identity, 96% coverage: 2:277/288 of query aligns to 7:278/290 of 8gsrA
6iymA Fumarylacetoacetate hydrolase (eafah) from psychrophilic exiguobacterium antarcticum (see paper)
44% identity, 80% coverage: 49:279/288 of query aligns to 47:276/277 of 6iymA
6v77B Crystal structure of a putative hpce protein from mycobacterium smegmatis
45% identity, 74% coverage: 64:276/288 of query aligns to 63:274/279 of 6v77B
8sutA Crystal structure of yisk from bacillus subtilis in complex with reaction product 4-hydroxy-2-oxoglutaric acid (see paper)
39% identity, 78% coverage: 53:277/288 of query aligns to 78:301/303 of 8sutA
8skyB Crystal structure of yisk from bacillus subtilis in complex with oxalate (see paper)
39% identity, 78% coverage: 53:277/288 of query aligns to 77:300/303 of 8skyB
3r6oA Crystal structure of a probable 2-hydroxyhepta-2,4-diene-1, 7- dioateisomerase from mycobacterium abscessus (see paper)
40% identity, 75% coverage: 63:277/288 of query aligns to 55:260/265 of 3r6oA
6j5xB Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate (see paper)
41% identity, 70% coverage: 71:271/288 of query aligns to 68:270/280 of 6j5xB
6j5xA Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate (see paper)
41% identity, 70% coverage: 71:271/288 of query aligns to 68:270/280 of 6j5xA
3qdfA Crystal structure of 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase from mycobacterium marinum (see paper)
42% identity, 73% coverage: 62:271/288 of query aligns to 54:241/252 of 3qdfA
4dbhA Crystal structure of cg1458 with inhibitor (see paper)
38% identity, 75% coverage: 56:272/288 of query aligns to 32:261/269 of 4dbhA
6sbiA X-ray structure of murine fumarylacetoacetate hydrolase domain containing protein 1 (fahd1) in complex with inhibitor oxalate (see paper)
38% identity, 72% coverage: 73:278/288 of query aligns to 14:214/216 of 6sbiA
6fogA X-ray structure of homo sapiens fumarylacetoacetate hydrolase domain containing protein 1 (fahd1) in complex with inhibitor oxalate at 1.94a resolution. (see paper)
38% identity, 69% coverage: 73:270/288 of query aligns to 15:207/218 of 6fogA
Sites not aligning to the query:
Q6P587 Acylpyruvase FAHD1, mitochondrial; Fumarylacetoacetate hydrolase domain-containing protein 1; FAH domain-containing protein 1; Oxaloacetate decarboxylase; OAA decarboxylase; YisK-like protein; EC 3.7.1.5; EC 4.1.1.112 from Homo sapiens (Human) (see 3 papers)
38% identity, 69% coverage: 73:270/288 of query aligns to 20:212/224 of Q6P587
1gttA Crystal structure of hpce (see paper)
37% identity, 67% coverage: 56:248/288 of query aligns to 206:392/421 of 1gttA
6j5yA Crystal structure of fumarylpyruvate hydrolase from pseudomonas aeruginosa in complex with mn2+ and pyruvate (see paper)
35% identity, 70% coverage: 69:271/288 of query aligns to 22:224/233 of 6j5yA
3v77A Crystal structure of a putative fumarylacetoacetate isomerase/hydrolase from oleispira antarctica (see paper)
35% identity, 62% coverage: 70:248/288 of query aligns to 15:197/224 of 3v77A
6jvwB Crystal structure of maleylpyruvate hydrolase from sphingobium sp. Syk-6 in complex with manganese (ii) ion and pyruvate (see paper)
34% identity, 76% coverage: 52:271/288 of query aligns to 54:254/264 of 6jvwB
1nkqA Crystal structure of yeast ynq8, a fumarylacetoacetate hydrolase family protein
31% identity, 67% coverage: 72:263/288 of query aligns to 10:218/247 of 1nkqA
3lzkC The crystal structure of a probably aromatic amino acid degradation protein from sinorhizobium meliloti 1021
26% identity, 52% coverage: 95:243/288 of query aligns to 116:270/343 of 3lzkC
Sites not aligning to the query:
>N515DRAFT_1252 FitnessBrowser__Dyella79:N515DRAFT_1252
MKLVRYGAHGNEKPGLIDKDGALRDLSEHVADIDPYVLGREGRARLAAIDPASLPEVEGT
PRFGAPVAPVSKIICVGMNYARHAAETGQPVPAQPVLFMKATTAIMGPNDDVVIPRGSTC
TDWEVELGVVIGETARDVSVDEALAHVAGFIVINDLSEREFQLEHGGQWVKGKSCDSFGP
LGPWLVTIDEVPDPQNLHLWLEVNGHRYQDSNTSDMVFGVAKLVSYISRYMTLLPGDVIS
TGTPAGVGLGLKPPTYLRPGDVIELGIDGLGRQRQQVRAHPADASAAR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory