Comparing N515DRAFT_2678 FitnessBrowser__Dyella79:N515DRAFT_2678 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
D4GSF3 SAMP-activating enzyme E1; Ubiquitin-like activating enzyme of archaea; Ubl-activating enzyme; EC 2.7.7.- from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
50% identity, 69% coverage: 119:386/388 of query aligns to 1:266/270 of D4GSF3
Q9VLJ8 Adenylyltransferase and sulfurtransferase MOCS3; Molybdenum cofactor synthesis protein 3; Ubiquitin activating enzyme 4; EC 2.7.7.80; EC 2.8.1.11 from Drosophila melanogaster (Fruit fly) (see paper)
45% identity, 65% coverage: 119:370/388 of query aligns to 60:310/453 of Q9VLJ8
Q72J02 Sulfur carrier protein adenylyltransferase; E1-like protein TtuC; Sulfur carrier protein MoaD adenylyltransferase; Sulfur carrier protein ThiS adenylyltransferase; Sulfur carrier protein TtuB adenylyltransferase; tRNA two-thiouridine-synthesizing protein C; EC 2.7.7.80; EC 2.7.7.73; EC 2.7.7.- from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see paper)
49% identity, 67% coverage: 110:370/388 of query aligns to 2:253/271 of Q72J02
Sites not aligning to the query:
P12282 Molybdopterin-synthase adenylyltransferase; MoaD protein adenylase; Molybdopterin-converting factor subunit 1 adenylase; Sulfur carrier protein MoaD adenylyltransferase; EC 2.7.7.80 from Escherichia coli (strain K12) (see 2 papers)
44% identity, 62% coverage: 130:371/388 of query aligns to 11:249/249 of P12282
O59954 Adenylyltransferase and sulfurtransferase uba4; Common component for nitrate reductase and xanthine dehydrogenase protein F; Ubiquitin-like protein activator 4; EC 2.7.7.80; EC 2.8.1.11 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
41% identity, 65% coverage: 123:374/388 of query aligns to 61:323/482 of O59954
1jwbB Structure of the covalent acyl-adenylate form of the moeb-moad protein complex (see paper)
43% identity, 62% coverage: 130:370/388 of query aligns to 10:240/240 of 1jwbB
1jw9B Structure of the native moeb-moad protein complex (see paper)
43% identity, 62% coverage: 130:370/388 of query aligns to 10:240/240 of 1jw9B
O95396 Adenylyltransferase and sulfurtransferase MOCS3; Molybdenum cofactor synthesis protein 3; Molybdopterin synthase sulfurylase; MPT synthase sulfurylase; EC 2.7.7.80; EC 2.8.1.11 from Homo sapiens (Human) (see 5 papers)
44% identity, 69% coverage: 121:388/388 of query aligns to 53:319/460 of O95396
Sites not aligning to the query:
P38820 Adenylyltransferase and sulfurtransferase UBA4; Needs CLA4 to survive protein 3; Ubiquitin-like protein activator 4; EC 2.7.7.-; EC 2.8.1.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
39% identity, 64% coverage: 123:372/388 of query aligns to 39:292/440 of P38820
Sites not aligning to the query:
6yubA Crystal structure of uba4 from chaetomium thermophilum (see paper)
39% identity, 55% coverage: 122:335/388 of query aligns to 5:214/423 of 6yubA
Sites not aligning to the query:
1jwaB Structure of the atp-bound moeb-moad protein complex (see paper)
40% identity, 60% coverage: 130:362/388 of query aligns to 10:217/217 of 1jwaB
6yubB Crystal structure of uba4 from chaetomium thermophilum (see paper)
39% identity, 55% coverage: 122:336/388 of query aligns to 6:214/289 of 6yubB
Sites not aligning to the query:
P30138 Sulfur carrier protein ThiS adenylyltransferase; EC 2.7.7.73 from Escherichia coli (strain K12) (see 3 papers)
39% identity, 62% coverage: 130:370/388 of query aligns to 8:244/251 of P30138
1zfnA Structural analysis of escherichia coli thif (see paper)
39% identity, 62% coverage: 130:370/388 of query aligns to 8:244/244 of 1zfnA
1zud3 Structure of this-thif protein complex (see paper)
36% identity, 62% coverage: 130:370/388 of query aligns to 8:239/240 of 1zud3
6mxvB The crystal structure of a rhodanese-like family protein from francisella tularensis subsp. Tularensis schu s4
40% identity, 27% coverage: 15:118/388 of query aligns to 142:248/251 of 6mxvB
Sites not aligning to the query:
3h9jA Crystal structure of e. Coli mccb + ampcpp + semet mcca (see paper)
26% identity, 68% coverage: 110:371/388 of query aligns to 70:339/339 of 3h9jA
3h5nA Crystal structure of e. Coli mccb + atp (see paper)
27% identity, 67% coverage: 110:370/388 of query aligns to 70:338/338 of 3h5nA
3h5rA Crystal structure of e. Coli mccb + succinimide (see paper)
26% identity, 68% coverage: 110:371/388 of query aligns to 70:340/340 of 3h5rA
Sites not aligning to the query:
3h5aC Crystal structure of e. Coli mccb (see paper)
26% identity, 68% coverage: 110:371/388 of query aligns to 70:348/358 of 3h5aC
>N515DRAFT_2678 FitnessBrowser__Dyella79:N515DRAFT_2678
MTESFNRESWLAQLRQQVPEIAPAEALTRQAGGALLIDVREDHERADGTPAGALGLSRGF
LELRIEQTEANRDRPILALCGSGQRSLLAAEALQRMGYRQVSSVAGGFNRWKAEGLPIVT
GALDADAAERYSRQLRLPQVGEAGQAKLGAARIVLLGAGGLGAPAALYLAAAGVGQITLI
DDDRVERSNLHRQVIHADARVGMAKTESARLALNALNPRVRIETREERLRADNVERLLAD
HDLVIDGADNFPARYLVAAASRRLGLPMVYGAVERFTGQVSVFDPRRDDAPCYRCLFPEP
PSAAEAPNCSEAGVLGVLPGLIGLLQATEALKLILELGETLSGRLLHVDALTMRFRETRL
RRDPSCPGCGQGAVFHGYEDIAELCASA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory