Comparing N515DRAFT_2885 FitnessBrowser__Dyella79:N515DRAFT_2885 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 12 hits to proteins with known functional sites (download)
D2Z028 L-serine/homoserine O-acetyltransferase; Homoserine O-trans-acetylase; EC 2.3.1.30; EC 2.3.1.31 from Streptomyces lavendulae (see paper)
62% identity, 98% coverage: 5:365/368 of query aligns to 8:370/374 of D2Z028
Q10341 Serine O-succinyltransferase; SST; EC 2.3.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
38% identity, 87% coverage: 7:325/368 of query aligns to 82:399/504 of Q10341
Sites not aligning to the query:
P45131 Homoserine O-acetyltransferase; HAT; Homoserine O-trans-acetylase; Homoserine transacetylase; HTA; EC 2.3.1.31 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 2 papers)
36% identity, 95% coverage: 14:361/368 of query aligns to 13:351/358 of P45131
Sites not aligning to the query:
5w8oB Homoserine transacetylase metx from mycobacterium hassiacum (see paper)
35% identity, 94% coverage: 15:361/368 of query aligns to 9:338/346 of 5w8oB
Q6FEQ3 Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.46 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
35% identity, 97% coverage: 9:366/368 of query aligns to 16:373/387 of Q6FEQ3
6ioiA Crystal structure of homoserine o-acetyltransferase in complex with coa from mycobacterium smegmatis atcc 19420 (see paper)
35% identity, 94% coverage: 15:361/368 of query aligns to 19:358/366 of 6ioiA
6iohA Crystal structure of homoserine o-acetyltransferase in complex with homoserine from mycobacterium smegmatis atcc 19420 (see paper)
35% identity, 94% coverage: 15:361/368 of query aligns to 19:358/375 of 6iohA
8f2lA Crystal structure of mycobacterium tuberculosis homoserine transacetylase in complex with l-homoserine (see paper)
33% identity, 95% coverage: 17:366/368 of query aligns to 20:362/367 of 8f2lA
7rytB Crystal structure of mycobacterium tuberculosis acetylated homoserine transacetylase with coenzyme a (see paper)
34% identity, 92% coverage: 28:366/368 of query aligns to 31:362/368 of 7rytB
6puxA Homoserine transacetylase metx from mycobacterium tuberculosis (see paper)
34% identity, 92% coverage: 28:366/368 of query aligns to 32:363/366 of 6puxA
2vavB Crystal structure of deacetylcephalosporin c acetyltransferase (dac- soak) (see paper)
32% identity, 96% coverage: 13:365/368 of query aligns to 17:347/350 of 2vavB
2vatA Crystal structure of deacetylcephalosporin c acetyltransferase in complex with coenzyme a (see paper)
32% identity, 96% coverage: 13:365/368 of query aligns to 16:345/347 of 2vatA
>N515DRAFT_2885 FitnessBrowser__Dyella79:N515DRAFT_2885
MSHDARRYFSLPSPFPMKRGGELHGARVAFETWGALSDARDNALLILTGLSPSAHAASNE
QDPSPGWWEAMIGPGKAIDTDRWFVICVNSLGSDKGSTCPASIDPATGEPYRLSFPELAL
EDVANAAHAAVSSLGIEQLACLVGCSMGGMSALAYMLLHPGSVRTHISVDTAPQAQPFAI
AIRSLQREAIRLDPQWNNGRYDDAHYPETGMSIARKLGVITYRSAMEWNGRFARIRLDAE
QRDDDVPFGFEFQVESYLEGHAQRFVRTFDPNSYLYLSRASDWFDISEYGEGSIQAGLKR
IRVEQALVIGVSTDILFPLEQQEQIAEGLEAAGAAVEFVALDSPQGHDAFLVDIENYSRA
IGGFLGRL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory