Comparing N515DRAFT_2934 FitnessBrowser__Dyella79:N515DRAFT_2934 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 5 hits to proteins with known functional sites (download)
7ac8B Molecular basis for the unique allosteric activation mechanism of the heterodimeric imidazole glycerol phosphate synthase complex. (see paper)
39% identity, 80% coverage: 40:195/196 of query aligns to 46:197/202 of 7ac8B
1ox5A Towards understanding the mechanism of the complex cyclization reaction catalyzed by imidazole glycerophosphate synthase (see paper)
34% identity, 99% coverage: 1:195/196 of query aligns to 4:213/532 of 1ox5A
Sites not aligning to the query:
1ox4B Towards understanding the mechanism of the complex cyclization reaction catalyzed by imidazole glycerophosphate synthase (see paper)
34% identity, 99% coverage: 1:195/196 of query aligns to 4:213/538 of 1ox4B
Sites not aligning to the query:
P33734 Imidazole glycerol phosphate synthase hisHF; IGP synthase; IGPS; ImGP synthase; EC 4.3.2.10; EC 3.5.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
34% identity, 99% coverage: 1:195/196 of query aligns to 1:210/552 of P33734
Sites not aligning to the query:
7yc6A Crystal structure of d110p mutant of gatase subunit of methanocaldococcus jannaschii gmp synthetase
21% identity, 99% coverage: 3:196/196 of query aligns to 2:177/183 of 7yc6A
>N515DRAFT_2934 FitnessBrowser__Dyella79:N515DRAFT_2934
MAVVLVDAGGTNIGSVRYALQRLGVDAALTSDANAIRQADRVILPGVGAAGPGMARLREL
GLVELIRSLTQPVLGVCLGMQLLFERSEEGATECLAVIPGAASRFAEAPGLRVPHMGWNR
LRVERAHPLVAGLGTDAWAYFVHSYAVPANDSTLATADFGGAFSAVVARGNFHGMQFHPE
RSAGVGARLLKNFLEL
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory