Comparing N515DRAFT_3366 FitnessBrowser__Dyella79:N515DRAFT_3366 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
7zlaB Cryo-em structure of holo-pdxr from bacillus clausii bound to its target DNA in the half-closed conformation (see paper)
34% identity, 94% coverage: 23:471/480 of query aligns to 14:449/458 of 7zlaB
Sites not aligning to the query:
7zn5B Cryo-em structure of holo-pdxr from bacillus clausii bound to its target DNA in the closed conformation, c2 symmetry. (see paper)
33% identity, 94% coverage: 23:471/480 of query aligns to 11:426/435 of 7zn5B
Sites not aligning to the query:
7pq9AAA PLP-dependent aminotransferase family protein (see paper)
35% identity, 70% coverage: 134:471/480 of query aligns to 13:353/367 of 7pq9AAA
3wx9A Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with pmp, gla, 4ad, 2og, glu and kya
30% identity, 73% coverage: 131:478/480 of query aligns to 40:398/404 of 3wx9A
Sites not aligning to the query:
3av7A Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with pmp, kyn as substrates and kya as products
30% identity, 73% coverage: 131:478/480 of query aligns to 40:398/404 of 3av7A
Sites not aligning to the query:
3aowC Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with akg
30% identity, 73% coverage: 131:478/480 of query aligns to 40:398/404 of 3aowC
Sites not aligning to the query:
3aovA Crystal structure of pyrococcus horikoshii kynurenine aminotransferase in complex with plp
30% identity, 73% coverage: 131:478/480 of query aligns to 40:398/404 of 3aovA
5t4kA Plp and gaba trigger gabr-mediated transcription regulation in bacillus subsidies via external aldimine formation (see paper)
35% identity, 71% coverage: 134:476/480 of query aligns to 12:355/360 of 5t4kA
Sites not aligning to the query:
5t4jB Plp and gaba trigger gabr-mediated transcription regulation in bacillus subsidies via external aldimine formation (see paper)
35% identity, 71% coverage: 134:476/480 of query aligns to 12:355/360 of 5t4jB
Sites not aligning to the query:
6uxzB (S)-4-amino-5-phenoxypentanoate as a selective agonist of the transcription factor gabr (see paper)
34% identity, 71% coverage: 134:476/480 of query aligns to 11:354/358 of 6uxzB
Sites not aligning to the query:
5x03B Crystal structure of thE C-terminal domain of bacillus subtilis gabr reveals a closed conformation by the binding of gamma-aminobutyric acid, inducing the transcriptional activation (see paper)
33% identity, 71% coverage: 134:476/480 of query aligns to 11:359/365 of 5x03B
1wstA Crystal structure of multiple substrate aminotransferase (msat) from thermococcus profundus
28% identity, 73% coverage: 131:478/480 of query aligns to 37:396/403 of 1wstA
2zc0A Crystal structure of an archaeal alanine:glyoxylate aminotransferase (see paper)
31% identity, 57% coverage: 131:402/480 of query aligns to 42:322/405 of 2zc0A
2z1yA Crystal structure of lysn, alpha-aminoadipate aminotransferase (complexed with n-(5'-phosphopyridoxyl)-l-leucine), from thermus thermophilus hb27
30% identity, 73% coverage: 127:478/480 of query aligns to 28:382/389 of 2z1yA
2zyjA Crystal structure of lysn, alpha-aminoadipate aminotransferase (complexed with n-(5'-phosphopyridoxyl)-l-glutamate), from thermus thermophilus hb27 (see paper)
30% identity, 73% coverage: 127:478/480 of query aligns to 36:390/397 of 2zyjA
Sites not aligning to the query:
Q72LL6 2-aminoadipate transaminase; 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT; EC 2.6.1.39 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 2 papers)
30% identity, 73% coverage: 127:478/480 of query aligns to 36:390/397 of Q72LL6
Sites not aligning to the query:
3cbfA Crystal structure of lysn, alpha-aminoadipate aminotransferase, from thermus thermophilus hb27 (see paper)
30% identity, 73% coverage: 127:478/480 of query aligns to 32:386/392 of 3cbfA
Sites not aligning to the query:
2egyA Crystal structure of lysn, alpha-aminoadipate aminotransferase (substrate free form), from thermus thermophilus hb27
30% identity, 73% coverage: 127:478/480 of query aligns to 32:386/392 of 2egyA
1vp4A Crystal structure of a putative aminotransferase (tm1131) from thermotoga maritima msb8 at 1.82 a resolution
26% identity, 65% coverage: 125:437/480 of query aligns to 40:369/420 of 1vp4A
8tn3A Structure of s. Hygroscopicus aminotransferase mppq complexed with pyridoxamine 5'-phosphate (pmp) (see paper)
30% identity, 60% coverage: 186:474/480 of query aligns to 82:383/388 of 8tn3A
>N515DRAFT_3366 FitnessBrowser__Dyella79:N515DRAFT_3366
MEHPFEFPLELPAKGSRQRLAALHTQLRAAILDGRLKAGLRLPATRELALALKLSRNTVV
AAYDLLLSEGYVVARRGAGNYVADLMERRARTHVAGTEEGGDRRLAPYWREARPPVPSPP
PGAFAHDFRLGVPDTRQFPFEVWRRLSARALRDVSRLPSMSGQSRGRPILREAIAQHVSF
ARAVACDPDDVMVTSGAQQAFDLLARVLVTPGKTVVAMEDPGYTPLRAAFAAAGARLVPV
AVDDEGIVVERIPVEARVIYVTPSHQFPLGMSMSPRRRAELLAFAAARRATVIEDDYDGE
FRYGGRPLDALQTLDREGSVCYVGTFSKCLFPALRIGYLVAPPWLLPALAAAKELADWHC
DVPAQDTLAAFIAEGHLARHVRRMRKIYAERREALLDALARHGLEAWPSDAGLHLSAKLP
RKLRTDVLVEQAAARGVRIEGLDGYTFGRASANGLALGYGLIEAARMDEAVRHIARLLPR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory