Comparing PP_1297 PP_1297 putative amino-acid ABC transporter-binding protein YhdW to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4z9nB Abc transporter / periplasmic binding protein from brucella ovis with glutathione bound
61% identity, 92% coverage: 28:342/342 of query aligns to 7:324/324 of 4z9nB
4zv1A An ancestral arginine-binding protein bound to arginine (see paper)
30% identity, 63% coverage: 35:250/342 of query aligns to 3:211/226 of 4zv1A
1xt8B Crystal structure of cysteine-binding protein from campylobacter jejuni at 2.0 a resolution (see paper)
29% identity, 62% coverage: 28:238/342 of query aligns to 6:208/251 of 1xt8B
4zv2A An ancestral arginine-binding protein bound to glutamine (see paper)
30% identity, 63% coverage: 35:250/342 of query aligns to 3:209/225 of 4zv2A
2yjpA Crystal structure of the solute receptors for l-cysteine of neisseria gonorrhoeae (see paper)
28% identity, 65% coverage: 27:250/342 of query aligns to 2:217/247 of 2yjpA
2v25A Structure of the campylobacter jejuni antigen peb1a, an aspartate and glutamate receptor with bound aspartate (see paper)
28% identity, 61% coverage: 29:236/342 of query aligns to 3:204/231 of 2v25A
2ia4B Crystal structure of novel amino acid binding protein from shigella flexneri
26% identity, 68% coverage: 25:256/342 of query aligns to 5:238/278 of 2ia4B
2vhaA Debp (see paper)
26% identity, 68% coverage: 25:256/342 of query aligns to 4:237/276 of 2vhaA
5t0wA Crystal structure of the ancestral amino acid-binding protein anccdt- 1, a precursor of cyclohexadienyl dehydratase
29% identity, 63% coverage: 27:243/342 of query aligns to 1:207/229 of 5t0wA
8ovoA X-ray structure of the sf-iglusnfr-s72a in complex with l-aspartate
26% identity, 68% coverage: 25:256/342 of query aligns to 2:235/503 of 8ovoA
5eyfB Crystal structure of solute-binding protein from enterococcus faecium with bound glutamate
25% identity, 59% coverage: 49:250/342 of query aligns to 26:220/243 of 5eyfB
6svfA Crystal structure of the p235gk mutant of argbp from t. Maritima (see paper)
25% identity, 64% coverage: 29:247/342 of query aligns to 3:210/229 of 6svfA
6h2tA Glnh bound to glu, mycobacterium tuberculosis (see paper)
30% identity, 40% coverage: 23:158/342 of query aligns to 39:173/288 of 6h2tA
Sites not aligning to the query:
3k4uE Crystal structure of putative binding component of abc transporter from wolinella succinogenes dsm 1740 complexed with lysine
25% identity, 61% coverage: 35:241/342 of query aligns to 3:203/234 of 3k4uE
6h20A Glnh bound to asn, mycobacterium tuberculosis (see paper)
30% identity, 40% coverage: 23:158/342 of query aligns to 38:172/287 of 6h20A
Sites not aligning to the query:
6h1uA Glnh bound to asp, mycobacterium tuberculosis (see paper)
30% identity, 40% coverage: 23:158/342 of query aligns to 38:172/287 of 6h1uA
Sites not aligning to the query:
4ymxA Crystal structure of the substrate binding protein of an amino acid abc transporter (see paper)
29% identity, 47% coverage: 36:197/342 of query aligns to 1:155/224 of 4ymxA
Sites not aligning to the query:
4zefA Crystal structure of substrate binding domain 2 (sbd2) of abc transporter glnpq from enterococcus faecalis
29% identity, 53% coverage: 33:213/342 of query aligns to 14:190/239 of 4zefA
3vv5A Crystal structure of ttc0807 complexed with (s)-2-aminoethyl-l- cysteine (aec) (see paper)
23% identity, 51% coverage: 28:200/342 of query aligns to 5:167/237 of 3vv5A
3vvfA Crystal structure of ttc0807 complexed with arginine (see paper)
23% identity, 51% coverage: 28:200/342 of query aligns to 9:171/241 of 3vvfA
Sites not aligning to the query:
>PP_1297 PP_1297 putative amino-acid ABC transporter-binding protein YhdW
MKMLKTTLAVLTAAAALGAVSTAQAGATLDAVKKKGFVQCGVSDGLPGFSVPDAQGKIVG
IDADVCRAVAAAVFGDATKVKFSQLNAKERFTALQSGEVDVLSRNTTWTSSRDAGMGLVF
AGVTYYDGVGFLVNKKLGVSSAKELDGATICIQAGTTTELNVSDFFRANGLKYTPITFDT
SDESAKSLESGRCDVLTSDKSQLFAQRSKLAAPTEYVVLPETISKEPLGPVVRKGDEEWF
SIVKWTLFAMLNAEEAGITSKNVEAEAKATKNPDVARLLGADGEYGKDLKLPKDWVVQIV
KQVGNYGEVFEKNLGQSTDLKIDRGMNALWNNGGIQYAPPVR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory