Comparing PP_1995 FitnessBrowser__Putida:PP_1995 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 5 hits to proteins with known functional sites (download)
1nsjA Crystal structure of phosphoribosyl anthranilate isomerase from thermotoga maritima (see paper)
46% identity, 98% coverage: 4:204/206 of query aligns to 2:203/205 of 1nsjA
1lbmA Crystal structure of phosphoribosyl anthranilate isomerase (prai) in complex with reduced 1-(o-carboxyphenylamino)-1-deoxyribulose 5- phosphate (rcdrp) (see paper)
44% identity, 98% coverage: 4:204/206 of query aligns to 2:192/194 of 1lbmA
1piiA Three-dimensional structure of the bifunctional enzyme phosphoribosylanthranilate isomerase: indoleglycerolphosphate synthase from escherichia coli refined at 2.0 angstroms resolution (see paper)
36% identity, 97% coverage: 6:204/206 of query aligns to 257:450/452 of 1piiA
Sites not aligning to the query:
7etxA Crystal structure of bifunctional indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase (trpc) from corynebacterium glutamicum (see paper)
30% identity, 89% coverage: 6:189/206 of query aligns to 260:446/472 of 7etxA
Sites not aligning to the query:
7etyA Crystal structure of bifunctional indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase (trpc) from corynebacterium glutamicum in complex with reduced 1-(o-carboxyphenylamino)-1- deoxyribulose 5-phosphate (rcdrp) (see paper)
30% identity, 89% coverage: 6:189/206 of query aligns to 258:444/470 of 7etyA
Sites not aligning to the query:
>PP_1995 FitnessBrowser__Putida:PP_1995
MSNVRSKICGITRIEDALAAAEAGADAIGFVFYAKSPRAVDVRQARAIIAELPPFVTTVG
LFVNASRCELNEILEVVPLDLLQFHGDETPQDCEGYHRPWIKALRVRPGDDLEAACRLYA
GARGILLDTYVPGVPGGTGEAFDWSLVPARLGKPIILAGGLSADNVGQAIAQVKPYAVDV
SGGVEQAKGIKDAAKIEAFMRAVKQA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory