Comparing PP_2137 FitnessBrowser__Putida:PP_2137 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
2d3tC Fatty acid beta-oxidation multienzyme complex from pseudomonas fragi, form v (see paper)
93% identity, 100% coverage: 2:391/391 of query aligns to 1:390/390 of 2d3tC
P45359 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; CaTHL; EC 2.3.1.9 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) (see paper)
42% identity, 98% coverage: 6:390/391 of query aligns to 2:391/392 of P45359
4xl4A Crystal structure of thiolase from clostridium acetobutylicum in complex with coa (see paper)
42% identity, 98% coverage: 6:390/391 of query aligns to 2:391/392 of 4xl4A
2vu2A Biosynthetic thiolase from z. Ramigera. Complex with s-pantetheine-11- pivalate. (see paper)
42% identity, 98% coverage: 8:391/391 of query aligns to 2:389/389 of 2vu2A
1dm3A Acetylated biosynthetic thiolase from zoogloea ramigera in complex with acetyl-coa (see paper)
42% identity, 98% coverage: 8:391/391 of query aligns to 2:389/389 of 1dm3A
1dlvA Biosynthetic thiolase from zoogloea ramigera in complex with coa (see paper)
42% identity, 98% coverage: 8:391/391 of query aligns to 2:389/389 of 1dlvA
2vu1A Biosynthetic thiolase from z. Ramigera. Complex of with o-pantheteine- 11-pivalate. (see paper)
42% identity, 98% coverage: 8:391/391 of query aligns to 4:391/391 of 2vu1A
1ou6A Biosynthetic thiolase from zoogloea ramigera in complex with acetyl-o- pantetheine-11-pivalate
42% identity, 98% coverage: 8:391/391 of query aligns to 5:392/392 of 1ou6A
8opuC Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with sulfamethoxazole (fragment-b-e1)
39% identity, 96% coverage: 15:391/391 of query aligns to 11:399/399 of 8opuC
8oqlC Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-1
39% identity, 96% coverage: 15:391/391 of query aligns to 11:397/397 of 8oqlC
Sites not aligning to the query:
2wkuA Biosynthetic thiolase from z. Ramigera. The n316h mutant. (see paper)
42% identity, 98% coverage: 8:391/391 of query aligns to 2:389/389 of 2wkuA
8oqoC Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-49
39% identity, 96% coverage: 15:391/391 of query aligns to 11:398/398 of 8oqoC
P07097 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Shinella zoogloeoides (Crabtreella saccharophila) (see 2 papers)
42% identity, 98% coverage: 9:391/391 of query aligns to 6:392/392 of P07097
8oqmD Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-10
39% identity, 96% coverage: 15:391/391 of query aligns to 12:399/399 of 8oqmD
8opyD Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-b-dnq
39% identity, 96% coverage: 15:391/391 of query aligns to 12:401/401 of 8opyD
5f38B X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution (see paper)
44% identity, 99% coverage: 6:391/391 of query aligns to 2:391/391 of 5f38B
6pccA Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex hexanoyl coenzyme a (see paper)
41% identity, 98% coverage: 7:391/391 of query aligns to 6:403/403 of 6pccA
6pcbA Crystal structure of beta-ketoadipyl-coa thiolase mutant (h356a) in complex with coa (see paper)
41% identity, 98% coverage: 7:391/391 of query aligns to 6:403/403 of 6pcbA
5f38D X-ray crystal structure of a thiolase from escherichia coli at 1.8 a resolution (see paper)
43% identity, 98% coverage: 6:390/391 of query aligns to 4:394/394 of 5f38D
1m1oA Crystal structure of biosynthetic thiolase, c89a mutant, complexed with acetoacetyl-coa (see paper)
42% identity, 98% coverage: 8:391/391 of query aligns to 3:390/390 of 1m1oA
>PP_2137 FitnessBrowser__Putida:PP_2137
MSLNPRDVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKLLERNGKVDPKEVEDVIWG
CVNQTLEQGWNIARMASLMTPIPHTSAAQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVG
GVEHMGHVSMMHGVDPNPHLSLHAAKASGMMGLTAEMLGKMHGITREQQDLFGLRSHQLA
HKATVEGKFKDEIIPMQGYDENGFLKVFDFDETIRPETTLEGLASLKPAFNPKGGTVTAG
TSSQITDGASCMIVMSGQRAMDLGIQPLAVIRSMAVAGVDPAIMGYGPVPSTQKALKRAG
LTMADIDFIELNEAFAAQALPVLKDLKVLDKMDEKVNLHGGAIALGHPFGCSGARISGTL
LNVMKQNGGTLGVATMCVGLGQGITTVFERV
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory