Comparing PP_2337 FitnessBrowser__Putida:PP_2337 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 7 hits to proteins with known functional sites (download)
Q8EJW4 2-methyl-aconitate isomerase; Cis-trans isomerase; EC 5.3.3.- from Shewanella oneidensis (strain MR-1) (see paper)
83% identity, 98% coverage: 5:392/396 of query aligns to 8:395/397 of Q8EJW4
5k87A Crystal structure of malonate bound to methylaconitate isomerase prpf from shewanella oneidensis (see paper)
82% identity, 98% coverage: 5:392/396 of query aligns to 4:387/389 of 5k87A
2pvzA Crystal structure of methylaconitate isomerase prpf from shewanella oneidensis (see paper)
82% identity, 98% coverage: 5:392/396 of query aligns to 4:385/387 of 2pvzA
2pw0A Crystal structure of trans-aconitate bound to methylaconitate isomerase prpf from shewanella oneidensis (see paper)
82% identity, 98% coverage: 5:392/396 of query aligns to 3:383/385 of 2pw0A
2pw0B Crystal structure of trans-aconitate bound to methylaconitate isomerase prpf from shewanella oneidensis (see paper)
74% identity, 98% coverage: 5:392/396 of query aligns to 4:339/341 of 2pw0B
6p3hC Crystal structure of ligu(k66m) bound to substrate (see paper)
37% identity, 96% coverage: 10:391/396 of query aligns to 6:351/352 of 6p3hC
6p3jB Crystal structure of ligu (see paper)
37% identity, 96% coverage: 10:391/396 of query aligns to 11:348/352 of 6p3jB
Sites not aligning to the query:
>PP_2337 FitnessBrowser__Putida:PP_2337
MSHVPQIKIPATYIRGGTSKGVFFRLQDLPEQAQIPGPARDALLLRVIGSPDPYGKQIDG
MGGATSSTSKTVILSQSIKPEHDVDYLFGQVSIDKAFVDWSGNCGNLSAAVGSFAISSGL
VDPARVPRNGIATVRIWQANIGKTIIAHVPITEGEVQETGDFELDGVTFPAAEVQLEFLD
PAADEDGGGGAMFPTGNLVDDLEVPGVGTFKATLINAGIPTIFVNAADIGYTGTELQDAI
NGDPQALLRFETIRAYGAVRMGLIDNVDQAAGRQHTPKVAFVAPPSTYTASSGKAVPAGE
IDLLVRALSMGKLHHAMMGTAAVAIGTAAAIPGTLVNLAAGGGERSAVRFGHPSGTLRVG
AEARQVNGEWTVTKAIMSRSARVLMEGWVRVPGDSF
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory