Comparing PP_2588 FitnessBrowser__Putida:PP_2588 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
6gwiB The crystal structure of halomonas elongata amino-transferase (see paper)
54% identity, 97% coverage: 10:455/460 of query aligns to 2:447/450 of 6gwiB
7q9xAAA Probable aminotransferase
54% identity, 95% coverage: 9:443/460 of query aligns to 1:435/455 of 7q9xAAA
4a6tC Crystal structure of the omega transaminase from chromobacterium violaceum in complex with plp (see paper)
54% identity, 95% coverage: 9:443/460 of query aligns to 1:435/455 of 4a6tC
6s4gA Crystal structure of the omega transaminase from chromobacterium violaceum in complex with pmp (see paper)
54% identity, 94% coverage: 11:443/460 of query aligns to 2:434/453 of 6s4gA
7qx0B Transaminase structure of plurienzyme (tr2e2) in complex with plp (see paper)
48% identity, 98% coverage: 10:458/460 of query aligns to 1:443/443 of 7qx0B
4ba5A Crystal structure of omega-transaminase from chromobacterium violaceum (see paper)
55% identity, 88% coverage: 38:443/460 of query aligns to 2:407/427 of 4ba5A
4a6rA Crystal structure of the omega transaminase from chromobacterium violaceum in the apo form, crystallised from polyacrylic acid (see paper)
55% identity, 88% coverage: 38:443/460 of query aligns to 1:403/423 of 4a6rA
7qx3A Structure of the transaminase tr2e2 with eos (see paper)
49% identity, 92% coverage: 38:458/460 of query aligns to 2:422/422 of 7qx3A
5ti8B Crystal structure of an aspartate aminotransferase from pseudomonas (see paper)
48% identity, 91% coverage: 38:454/460 of query aligns to 1:380/384 of 5ti8B
7ypmA Crystal structure of transaminase cc1012 complexed with plp and l- alanine (see paper)
45% identity, 94% coverage: 18:451/460 of query aligns to 10:445/454 of 7ypmA
7ypnD Crystal structure of transaminase cc1012 mutant m9 complexed with plp (see paper)
45% identity, 94% coverage: 18:451/460 of query aligns to 10:445/455 of 7ypnD
6io1B Crystal structure of a novel thermostable (s)-enantioselective omega- transaminase from thermomicrobium roseum (see paper)
41% identity, 95% coverage: 16:451/460 of query aligns to 10:444/448 of 6io1B
5kr6B Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
40% identity, 97% coverage: 10:454/460 of query aligns to 5:457/460 of 5kr6B
6g4fA Crystal structure of the omega transaminase from pseudomonas jessenii in complex with pmp (see paper)
37% identity, 96% coverage: 18:458/460 of query aligns to 7:450/451 of 6g4fA
6g4eA Crystal structure of the omega transaminase from pseudomonas jessenii in complex with plp and 6-aminohexanoate (6-aca) (see paper)
37% identity, 96% coverage: 18:458/460 of query aligns to 7:450/451 of 6g4eA
6g4dB Crystal structure of the omega transaminase from pseudomonas jessenii in complex with plp (see paper)
37% identity, 96% coverage: 18:458/460 of query aligns to 7:450/453 of 6g4dB
5kr5A Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
39% identity, 91% coverage: 38:454/460 of query aligns to 31:453/455 of 5kr5A
5kr3A Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
39% identity, 96% coverage: 18:457/460 of query aligns to 12:457/458 of 5kr3A
5ghgB Transaminase w58l with smba
38% identity, 93% coverage: 15:443/460 of query aligns to 5:417/433 of 5ghgB
5kquC Directed evolution of transaminases by ancestral reconstruction. Using old proteins for new chemistries
38% identity, 95% coverage: 18:454/460 of query aligns to 11:455/459 of 5kquC
>PP_2588 FitnessBrowser__Putida:PP_2588
MNAPFAPQRQTRDYQAADAAHHIHAFLDQKALNAEGPRVIVGGERLHLWDSEGKRYLDGM
SGLWCTQLGYGRRDLTAAAATQMDQLAYYNMFFHTTHPAVIELSELLFSLLPGHYSHAIY
TNSGSEANEVLIRTVRRYWQVVGQPGKKIMIGRWNGYHGSTLAATALGGMKFMHDMGGLI
PDVAHIDEPYWYAEGGELTPAEFGRRCALQLEEKILELGAENVAGFIAEPFQGAGGMIFP
PESYWPEIQRICRQYDVLLCADEVIGGFGRTGEWFAHEYFGFEPDTLSIAKGLTSGYVPM
GGLVLSKRIAEALVERGGVFAHGLTYSGHPVAAAVAIANLKALRDEGIVRQVKDDTGPYL
QRILREVFADHPLIGQVQGAGLVAALQFAEHKPTRKRFANENDLAWQCRTFGFEEGVIIR
STLGRMIMAPALIANHSELDELVEKTRIAVDRTARLVGKL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory